tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huh KH et al. | De novo low-dose sirolimus versus mycophenolate mofetil in combination with extended-release tacrolimus in kidney transplant recipients: a multicentre, open-label, randomized, controlled, non-inferiority trial. | 2017 | Nephrol. Dial. Transplant. | pmid:28810721 |
| Choi SW et al. | Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT. | 2017 | Blood | pmid:28784598 |
| Kurzawski M et al. | Analysis of common polymorphisms within NR1I2 and NR1I3 genes and tacrolimus dose-adjusted concentration in stable kidney transplant recipients. | 2017 | Pharmacogenet. Genomics | pmid:28777242 |
| Willerth SM | Localized Tacrolimus Delivery Repairs the Damaged Central Nervous System. | 2017 | EBioMedicine | pmid:29195745 |
| Lloberas N et al. | The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation. | 2017 | Pharmacogenet. Genomics | pmid:28704257 |
| Saito R et al. | Two cases of eczematous drug eruption caused by oral tacrolimus administration. | 2017 | Contact Derm. | pmid:28703346 |
| Martial LC et al. | Dried Blood Spot Sampling for Tacrolimus and Mycophenolic Acid in Children: Analytical and Clinical Validation. | 2017 | Ther Drug Monit | pmid:28700522 |
| Ruiz S et al. | Tacrolimus rescues the signaling and gene expression signature of endothelial ALK1 loss-of-function and improves HHT vascular pathology. | 2017 | Hum. Mol. Genet. | pmid:28973643 |
| Lee JE et al. | A Case of Rheumatoid Vasculitis Involving Hepatic Artery in Early Rheumatoid Arthritis. | 2017 | J. Korean Med. Sci. | pmid:28581281 |
| Riva N et al. | Pharmacoepidemiology of tacrolimus in pediatric liver transplantation. | 2017 | Pediatr Transplant | pmid:28574195 |
| Wu H et al. | Novel self-assembled tacrolimus nanoparticles cross-linking thermosensitive hydrogels for local rheumatoid arthritis therapy. | 2017 | Colloids Surf B Biointerfaces | pmid:27736727 |
| Damon C et al. | Predictive Modeling of Tacrolimus Dose Requirement Based on High-Throughput Genetic Screening. | 2017 | Am. J. Transplant. | pmid:27597269 |
| Donati M et al. | Resolution of Benign and Malignant Sebaceous Neoplasms, in a Renal Transplant Patient Treated With Everolimus. | 2017 | Exp Clin Transplant | pmid:25924010 |
| Kim YJ et al. | Two cases of hydroa vacciniforme-like lymphoproliferative disease controlled by anti-inflammatory agents. | 2017 | Photodermatol Photoimmunol Photomed | pmid:28543883 |
| Zong YP et al. | Effects of CYP3A5 polymorphisms on tacrolimus pharmacokinetics in pediatric kidney transplantation: a systematic review and meta-analysis of observational studies. | 2017 | World J Pediatr | pmid:28540692 |
| Gooptu M and Koreth J | Better acute graft--host disease outcomes for allogeneic transplant recipients in the modern era: a tacrolimus effect? | 2017 | Haematologica | pmid:28458253 |
| Costa JS et al. | Polyomavirus Nephropathy: Ten-Year Experience. | 2017 | Transplant. Proc. | pmid:28457399 |
| Chiasson VL et al. | Regulatory T-Cell Augmentation or Interleukin-17 Inhibition Prevents Calcineurin Inhibitor-Induced Hypertension in Mice. | 2017 | Hypertension | pmid:28584011 |
| Shoda W et al. | Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake. | 2017 | Kidney Int. | pmid:28341239 |
| Cakir U et al. | Role of Everolimus on Cardiac Functions in Kidney Transplant Recipients. | 2017 | Transplant. Proc. | pmid:28340820 |
| Hettiarachchi PVKS et al. | Comparison of topical tacrolimus and clobetasol in the management of symptomatic oral lichen planus: A double-blinded, randomized clinical trial in Sri Lanka. | 2017 | J Investig Clin Dent | pmid:27633647 |
| Ciftci HS et al. | Influence of Proton Pump Inhibitors on Mycophenolic Acid Pharmacokinetics in Patients With Renal Transplantation and the Relationship With Cytochrome 2C19 Gene Polymorphism. | 2017 | Transplant. Proc. | pmid:28340819 |
| Rodrigues N et al. | Serum Magnesium and Related Factors in Long-Term Renal Transplant Recipients: An Observational Study. | 2017 | Transplant. Proc. | pmid:28457398 |
| Terada Y et al. | Tacrolimus Triggers Transient Receptor Potential Vanilloid-1-Dependent Relapse of Pancreatitis-Related Pain in Mice. | 2017 | Pharmacology | pmid:28253495 |
| Zhang X et al. | Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients. | 2017 | Dis. Markers | pmid:28246425 |
| Mashayekhi S et al. | The treatment of vulval lichen sclerosus in prepubertal girls: a critically appraised topic. | 2017 | Br. J. Dermatol. | pmid:28244087 |
| Kanai T et al. | Adequate tacrolimus concentration for myasthenia gravis treatment. | 2017 | Eur. J. Neurol. | pmid:28102047 |
| Sarier M et al. | HPV type 45-positive condyloma acuminata of the bladder in a renal transplant recipient. | 2017 | Transpl Infect Dis | pmid:28100036 |
| Fan B et al. | Prograf produces more benefits for CYP3A5 low expression patients in early stage after kidney transplantation. | 2017 | Biomed. Pharmacother. | pmid:28157649 |
| Hanchanale P et al. | Nocardia liver abscess post liver transplantation-A rare presentation. | 2017 | Transpl Infect Dis | pmid:28150374 |
| Juvvadi PR et al. | Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach. | 2017 | Virulence | pmid:27325145 |
| D'Avola D et al. | Cardiovascular morbidity and mortality after liver transplantation: The protective role of mycophenolate mofetil. | 2017 | Liver Transpl. | pmid:28160394 |
| Kaneshiro S et al. | The efficacy and safety of additional administration of tacrolimus in patients with rheumatoid arthritis who showed an inadequate response to tocilizumab. | 2017 | Mod Rheumatol | pmid:27181115 |
| Andreu F et al. | A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach. | 2017 | Clin Pharmacokinet | pmid:28050888 |
| Shimizu K | Development of New Liposome Targeting Strategies for Application of Disease Therapies. | 2017 | Yakugaku Zasshi | pmid:28049894 |
| Cukor D et al. | A Pilot Randomized Controlled Trial to Promote Immunosuppressant Adherence in Adult Kidney Transplant Recipients. | 2017 | Nephron | pmid:28049201 |
| Maneechote C et al. | Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury. | 2017 | J. Cell. Mol. Med. | pmid:28941171 |
| Baskiran A et al. | Pregnancy After Liver Transplantation: Risks and Outcomes. | 2017 | Transplant. Proc. | pmid:28923640 |
| Shi G et al. | Variation of CD4CD25Foxp3 Regulatory T Cells and Th17 Cells in the Peripheral Blood of Human Liver Allograft Patients With Long-term Survival. | 2017 | Transplant. Proc. | pmid:28923634 |
| Shrestha BM | Two Decades of Tacrolimus in Renal Transplant: Basic Science and Clinical Evidences. | 2017 | Exp Clin Transplant | pmid:27938316 |
| Weininger U et al. | Dynamics of Aromatic Side Chains in the Active Site of FKBP12. | 2017 | Biochemistry | pmid:27936610 |
| Hosoi K et al. | Prolonged tacrolimus for pediatric gastrointestinal disorder: Double-edged sword? | 2017 | Pediatr Int | pmid:27935231 |
| Yu MY et al. | Short-term anti-proteinuric effect of tacrolimus is not related to preservation of the glomerular filtration rate in IgA nephropathy: A 5-year follow-up study. | 2017 | PLoS ONE | pmid:29155873 |
| Alloway RR et al. | Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial. | 2017 | PLoS Med. | pmid:29135993 |
| Parrow NL and Fleming RE | Releasing the FKBP12 brake on hepcidin. | 2017 | Blood | pmid:29122771 |
| Gonzalez-Andrades M et al. | Sterile Corneal Infiltrates Secondary to Psoriasis Exacerbations: Topical Tacrolimus as an Alternative Treatment Option. | 2017 | Eye Contact Lens | pmid:26222098 |
| Olmedo MartÃn RV et al. | Medium to long-term efficacy and safety of oral tacrolimus in moderate to severe steroid refractory ulcerative colitis. | 2017 | Rev Esp Enferm Dig | pmid:28617029 |
| Maldonado AQ et al. | Prevalence of CYP3A5 Genomic Variances and Their Impact on Tacrolimus Dosing Requirements among Kidney Transplant Recipients in Eastern North Carolina. | 2017 | Pharmacotherapy | pmid:28605053 |
| Esquirol A et al. | Single-agent GvHD prophylaxis with tacrolimus after post-transplant high-dose cyclophosphamide is a valid option for haploidentical transplantation in adults with hematological malignancies. | 2017 | Bone Marrow Transplant. | pmid:28604667 |
| Pietrosi G and Chinnici C | Report on Liver Cell Transplantation Using Human Fetal Liver Cells. | 2017 | Methods Mol. Biol. | pmid:27830561 |