tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yamaguchi K et al. | [Case of encephalopathy seemingly caused by tacrolimus at blood concentration near the upper limit of therapeutic range]. | 2012 | Yakugaku Zasshi | pmid:22790031 |
| Sood S and Muthuraman A | Activity of tacrolimus: an immunosuppressant, in pyloric ligation-induced peptic ulcer in the rat. | 2009 | Yakugaku Zasshi | pmid:19952532 |
| Tanaka H et al. | [Discovery and development of a novel immunosuppressant, tacrolimus hydrate]. | 1997 | Yakugaku Zasshi | pmid:9306728 |
| Muraki Y | [Factors affecting the pharmacokinetics after living donor liver transplant]. | 2012 | Yakugaku Zasshi | pmid:23023417 |
| Uchida K et al. | Pharmacokinetics of orally administered tacrolimus in lupus nephritis patients. | 2010 | Yakugaku Zasshi | pmid:20046074 |
| Tanaka Y et al. | [Effect of tacrolimus on the pharmacokinetics and glucuronidation of SN-38, an active metabolite of irinotecan]. | 2013 | Yakugaku Zasshi | pmid:23328499 |
| Wang M et al. | Studies on the effects of the immunosuppressant FK-506 on the high-risk corneal graft rejection. | 2002 | Yan Ke Xue Bao | pmid:15510746 |
| Li S et al. | Experiment study of retinal ultrastructure after intravitreal FK506. | 2004 | Yan Ke Xue Bao | pmid:15124532 |
| Xie H et al. | Effect of topical FK506 used alone or combined with keratoplasty on patients with recurrent Mooren's corneal ulcer. | 2006 | Yan Ke Xue Bao | pmid:17378150 |
| Ma H et al. | [The effect of FK506 on the proliferation of HRCECs]. | 2006 | Yan Ke Xue Bao | pmid:17378157 |
| Zhang GM et al. | [Population pharmacokinetics of tacrolimus in Chinese renal transplant patients]. | 2008 | Yao Xue Xue Bao | pmid:18819472 |
| Deng CH et al. | [The therapeutic drug monitoring network server of tacrolimus for Chinese renal transplant patients]. | 2011 | Yao Xue Xue Bao | pmid:22010353 |
| Guan Z et al. | [Application of Fourier amplitude sensitivity test in Chinese healthy volunteer population pharmacokinetic model of tacrolimus]. | 2010 | Yao Xue Xue Bao | pmid:20931787 |
| Xue L et al. | [Population pharmacokinetic study of tacrolimus in patients with hematopoietic stem cell transplant]. | 2009 | Yao Xue Xue Bao | pmid:20055140 |
| Zhang YJ et al. | [Hypertrophy of the heart: calcineurin-NFAT pathway may be a new therapeutic target]. | 2006 | Yao Xue Xue Bao | pmid:17184105 |
| Zhu L et al. | [Effect of CYP3A4*18B, CYP3A5*3 gene polymorphism on dosage and concentration of tacrolimus in renal transplant patients]. | 2012 | Yao Xue Xue Bao | pmid:22993851 |
| Fu XH et al. | [Prediction of blood tacrolimus concentration in liver transplantation recipients by artificial neural network]. | 2012 | Yao Xue Xue Bao | pmid:23227541 |
| Partaledis JA et al. | Saccharomyces cerevisiae contains a homolog of human FKBP-13, a membrane-associated FK506/rapamycin binding protein. | 1992 | Yeast | pmid:1279908 |
| Lee JH et al. | Withdrawal of immunosuppression in pediatric liver transplant recipients in Korea. | 2009 | Yonsei Med. J. | pmid:20046418 |
| First MR and Fitzsimmons WE | Modified release tacrolimus. | 2004 | Yonsei Med. J. | pmid:15627307 |