tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Radziejewski K et al. | Assessment of corneal and conjunctival metaplasia by impression cytology during the treatment of canine keratoconjunctivitis sicca. | 2018 | Acta Vet. Hung. | pmid:29958527 |
| Gómez-Bravo MA et al. | Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients. | 2018 | Pharmacogenet. Genomics | pmid:29256966 |
| Tanaka Y et al. | Cooperation between ER stress and calcineurin signaling contributes to the maintenance of cell wall integrity in Candida glabrata. | 2018 | Fungal Biol | pmid:29248112 |
| Sikma MA et al. | Association of Whole Blood Tacrolimus Concentrations with Kidney Injury in Heart Transplantation Patients. | 2018 | Eur J Drug Metab Pharmacokinet | pmid:29236211 |
| Leiskau C et al. | Side effects and efficacy of renal sparing immunosuppression in pediatric liver transplantation-A single center matched cohort study. | 2018 | Pediatr Transplant | pmid:29729061 |
| Kamanamool N et al. | Comparison of disease activity between tacrolimus and mycophenolate mofetil in lupus nephritis: a randomized controlled trial. | 2018 | Lupus | pmid:29105558 |
| Fu J et al. | Transcriptomic analysis uncovers novel synergistic mechanisms in combination therapy for lupus nephritis. | 2018 | Kidney Int. | pmid:29102373 |
| Lamanna JJ et al. | Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord. | 2018 | J Clin Neurosci | pmid:29089163 |
| Cuñetti L et al. | Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay. | 2018 | Transplant. Proc. | pmid:29579828 |
| Armenta Bautista A et al. | Renal Transplantation in Second-Level Private Hospitals in the State of Mexico. | 2018 | Transplant. Proc. | pmid:29579825 |
| Zeng K et al. | Dissolution Test of Tacrolimus Capsule: Effects of Filtration and Glass Adsorption. | 2018 | AAPS PharmSciTech | pmid:28828626 |
| Kim JP et al. | The effect of full dose composite tissue allotransplantation immunosuppression on allograft motor nerve regeneration in a rat sciatic nerve model. | 2018 | Microsurgery | pmid:28792625 |
| Chandran SR et al. | A Model of Acute Antibody-Mediated Renal Allograft Rejection in the Sensitized Rata. | 2018 | Exp Clin Transplant | pmid:28760115 |
| Zheng CS et al. | Assessment of the synergic effect of immunomodulation on nerve repair using multiparametric magnetic resonance imaging. | 2018 | Muscle Nerve | pmid:28445921 |
| Gómez-RÃos GA et al. | Rapid determination of immunosuppressive drug concentrations in whole blood by coated blade spray-tandem mass spectrometry (CBS-MS/MS). | 2018 | Anal. Chim. Acta | pmid:29254576 |
| Lancia P et al. | Adverse Events under Tacrolimus and Cyclosporine in the First 3 Years Post-Renal Transplantation in Children. | 2018 | Clin Drug Investig | pmid:29236209 |
| Park CS et al. | Tetrahydrocurcumin Ameliorates Tacrolimus-Induced Nephrotoxicity Via Inhibiting Apoptosis. | 2018 | Transplant. Proc. | pmid:30401411 |
| Hiramatsu Y et al. | Changes in the blood level, efficacy, and safety of tacrolimus in pregnancy and the lactation period in patients with systemic lupus erythematosus. | 2018 | Lupus | pmid:30394835 |
| Ordóñez-Robles M et al. | Genome-wide transcriptome response of Streptomyces tsukubaensis to N-acetylglucosamine: effect on tacrolimus biosynthesis. | 2018 | Microbiol. Res. | pmid:30384905 |
| Hamano I et al. | Condyloma Acuminata of the Urethra in a Male Renal Transplant Recipient: A Case Report. | 2018 | Transplant. Proc. | pmid:30316397 |
| Choong CL et al. | Dose-Response Relationship Between Diltiazem and Tacrolimus and Its Safety in Renal Transplant Recipients. | 2018 | Transplant. Proc. | pmid:30316389 |
| Saengram W et al. | Extended release versus immediate release tacrolimus in kidney transplant recipients: a systematic review and meta-analysis. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29961086 |
| Tunnicliffe DJ et al. | Immunosuppressive treatment for proliferative lupus nephritis. | 2018 | Cochrane Database Syst Rev | pmid:29957821 |
| Sugahara S et al. | Integrin, alpha9 subunit blockade suppresses collagen-induced arthritis with minimal systemic immunomodulation. | 2018 | Eur. J. Pharmacol. | pmid:29932925 |
| Wen L et al. | Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice. | 2018 | Gastroenterology | pmid:29928898 |
| Marquet P et al. | Comparative clinical trial of the variability factors of the exposure indices used for the drug monitoring of two tacrolimus formulations in kidney transplant recipients. | 2018 | Pharmacol. Res. | pmid:29229354 |
| Zhang T et al. | Association of donor small ubiquitin-like modifier 4 rs237025 genetic variant with tacrolimus elimination in the early period after liver transplantation. | 2018 | Liver Int. | pmid:28941036 |
| Scherrer M et al. | Tacrolimus-induced symmetric drug-related intertriginous and flexural exanthema (SDRIFE). | 2018 | Contact Derm. | pmid:29722025 |
| Del Bello A et al. | High tacrolimus intra-patient variability is associated with graft rejection, and donor-specific antibodies occurrence after liver transplantation. | 2018 | World J. Gastroenterol. | pmid:29713132 |
| Lin G et al. | Evaluation of tacrolimus-related CYP3A5 genotyping in China: Results from the First External Quality Assessment Exercise. | 2018 | J. Clin. Lab. Anal. | pmid:29708622 |
| Luaces-RodrÃguez A et al. | Preclinical characterization and clinical evaluation of tacrolimus eye drops. | 2018 | Eur J Pharm Sci | pmid:29705214 |
| Castedal M et al. | Steroid-free immunosuppression with low-dose tacrolimus is safe and significantly reduces the incidence of new-onset diabetes mellitus following liver transplantation. | 2018 | Scand. J. Gastroenterol. | pmid:29688072 |
| Niel O and Bastard P | Artificial intelligence improves estimation of tacrolimus area under the concentration over time curve in renal transplant recipients. | 2018 | Transpl. Int. | pmid:29687486 |
| Hong D et al. | [Atopic keratoconjunctivitis: One allergy may mask another. A clinical observation with two types of hypersensitivity reactions: IgE-mediated and non-IgE-mediated]. | 2018 | J Fr Ophtalmol | pmid:29567021 |
| Ekici Günay N et al. | Administration of Extract (EGb761) Alone and in Combination with FK506 Promotes Liver Regeneration in a Rat Model of Partial Hepatectomy. | 2018 | Balkan Med J | pmid:29553465 |
| Zhang X et al. | Current progress of tacrolimus dosing in solid organ transplant recipients: Pharmacogenetic considerations. | 2018 | Biomed. Pharmacother. | pmid:29550633 |
| Komine N et al. | Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitial fibrosis and long-term graft function in kidney transplant recipients. | 2018 | Int. Immunopharmacol. | pmid:29550576 |
| Jouve T et al. | Tailoring tacrolimus therapy in kidney transplantation. | 2018 | Expert Rev Clin Pharmacol | pmid:29779413 |
| Qin X et al. | Multi-center Performance Evaluations of Tacrolimus and Cyclosporine Electrochemiluminescence Immunoassays in the Asia-Pacific Region. | 2018 | Ann Lab Med | pmid:29214751 |
| Chen X et al. | A case report of lupus erythematosus tumidus converted from discoid lupus erythematosus. | 2018 | Medicine (Baltimore) | pmid:29668590 |
| Li A et al. | Atopic keratoconjunctivitis: A diagnostic dilemma-a case report. | 2018 | Medicine (Baltimore) | pmid:29668589 |
| Fu Q et al. | Risk Factors for Acute Rejection After Deceased Donor Kidney Transplantation in China. | 2018 | Transplant. Proc. | pmid:30316380 |
| Konno O et al. | Early Outcomes of Living-Donor Kidney Transplantation With Immunosuppression Therapy Induction With Tacrolimus Extended-Release: A Comparison With Cyclosporine. | 2018 | Transplant. Proc. | pmid:30316378 |
| Yang Y et al. | Chlormethine Hydrochloride is Not Inferior to Tacrolimus in Treating Steroid-Resistant Nephrotic Syndrome. | 2018 | Kidney Blood Press. Res. | pmid:29402844 |
| Gadby F et al. | [Pulmonary granuloma in an immunodepressed patient]. | 2018 | Rev Mal Respir | pmid:29395568 |
| Onodera M et al. | Tacrolimus Dose Optimization Strategy for Refractory Ulcerative Colitis Based on the Cytochrome P450 3A5 Polymorphism Prediction Using Trough Concentration after 24 Hours. | 2018 | Digestion | pmid:29393157 |
| Liu YC et al. | A Biodegradable, Sustained-Released, Tacrolimus Microfilm Drug Delivery System for the Management of Allergic Conjunctivitis in a Mouse Model. | 2018 | Invest. Ophthalmol. Vis. Sci. | pmid:29392313 |
| Yu M et al. | Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation. | 2018 | Curr. Drug Metab. | pmid:29380698 |
| Kim JH et al. | Increased Exposure of Tacrolimus by Co-administered Mycophenolate Mofetil: Population Pharmacokinetic Analysis in Healthy Volunteers. | 2018 | Sci Rep | pmid:29374217 |
| Murad A et al. | Primary cutaneous post liver transplant lymphoproliferative disorder (PTLD) successfully treated with radiotherapy. | 2018 | J Dermatolog Treat | pmid:28604230 |