tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tomono M et al. | Inhibitors of calcineurin block expression of cyclins A and E induced by fibroblast growth factor in Swiss 3T3 fibroblasts. | 1998 | Arch. Biochem. Biophys. | pmid:9606972 |
| Singer NG and McCune WJ | Update on immunosuppressive therapy. | 1998 | Curr Opin Rheumatol | pmid:9608317 |
| Ito H et al. | Myoblast transplantation in non-dystrophic dog. | 1998 | Neuromuscul. Disord. | pmid:9608563 |
| Kliem V and Brunkhorst R | Tacrolimus in kidney transplantation. A clinical review. | 1998 | Nephron | pmid:9609456 |
| Samsó M and Wagenknecht T | Contributions of electron microscopy and single-particle techniques to the determination of the ryanodine receptor three-dimensional structure. | 1998 | J. Struct. Biol. | pmid:9615436 |
| Tomás ML | [Immunosuppressive agents: side effects]. | 1997 | An R Acad Nac Med (Madr) | pmid:9616947 |
| Idilman R et al. | Immunosuppressive drug-induced leukoencephalopathy in patients with liver transplant. | 1998 | Eur J Gastroenterol Hepatol | pmid:9619393 |
| Kikuchi M et al. | Protective effects of FK506 against glutamate-induced neurotoxicity in retinal cell culture. | 1998 | Invest. Ophthalmol. Vis. Sci. | pmid:9620083 |
| Lampen A et al. | Catalytic activities, protein- and mRNA-expression of cytochrome P450 isoenzymes in intestinal cell lines. | 1998 | Xenobiotica | pmid:9622846 |
| Schulman SL et al. | Interaction between tacrolimus and chloramphenicol in a renal transplant recipient. | 1998 | Transplantation | pmid:9625026 |
| Pruvot FR and Noel C | Comment on "Pregnancy after liver transplantation under tacrolimus" by Jain et al. | 1998 | Transplantation | pmid:9625033 |
| Takada Y et al. | Prolonged hepatic warm ischemia in non-heart-beating donors: protective effects of FK506 and a platelet activating factor antagonist in porcine liver transplantation. | 1998 | Surgery | pmid:9626320 |
| Ellouk-Achard S et al. | FK506 (Tacrolimus) decreases the cytotoxicity of cyclosporin A in rat hepatocytes in primary culture: implication of CYP3A induction. | 1998 | Arch. Toxicol. | pmid:9630010 |
| Starzl TE et al. | Tacrolimus (FK506) and the pharmaceutical/academic/regulatory gauntlet. | 1998 | Am. J. Kidney Dis. | pmid:9631858 |
| Al-Awwa IA et al. | Importance of allograft biopsy in renal transplant recipients: correlation between clinical and histological diagnosis. | 1998 | Am. J. Kidney Dis. | pmid:9631859 |
| Tredger JM et al. | Therapeutic monitoring of tacrolimus (FK506) with the first- and second-generation microparticle enzyme immunoassays: performance and results in four patient populations. | 1998 | Ther Drug Monit | pmid:9631923 |
| Nicholson ML et al. | Is TGF-beta a profibrotic cytokine in human renal transplants? | 1998 | Transplant. Proc. | pmid:9636384 |
| Ginevri F et al. | Expression of collagen by renal fibroblasts treated with FK 506 in vitro. | 1998 | Transplant. Proc. | pmid:9636387 |
| Hutchinson IV et al. | Differences in the mode of action of cyclosporine and FK 506. | 1998 | Transplant. Proc. | pmid:9636388 |
| Müller V et al. | Effect of mycophenolate mofetil on the in vivo infiltration of lymphocytes in the rat remnant kidney. | 1998 | Transplant. Proc. | pmid:9636396 |