Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Roche, FDA announce new drug-interaction warnings for mibefradil. | 1998 | Am J Health Syst Pharm | pmid:9492249 | |
Ku YM et al. | Compatibility of tacrolimus injection with cimetidine hydrochloride injection in 0.9% sodium chloride injection. | 1995 | Am J Health Syst Pharm | pmid:8528874 |
Greanya ED et al. | Pharmacokinetics of tacrolimus and mycophenolate mofetil in renal transplant recipients on a corticosteroid-free regimen. | 2012 | Am J Health Syst Pharm | pmid:22215359 |
Curtin BF et al. | Unusually late-onset mycophenolate mofetil-related colitis. | 2014 | Am J Health Syst Pharm | pmid:25320135 |
Lee JH et al. | Stability of tacrolimus solutions in polyolefin containers. | 2016 | Am J Health Syst Pharm | pmid:26796907 |
Tacrolimus. | 2001 | Am J Health Syst Pharm | pmid:11794952 | |
Lee B et al. | Appropriate timing of tacrolimus concentration measurements in the emergency department. | 2016 | Am J Health Syst Pharm | pmid:27543574 |
Utecht KN et al. | Effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors. | 2006 | Am J Health Syst Pharm | pmid:17106006 |
Kelly PA et al. | Tacrolimus: a new immunosuppressive agent. | 1995 | Am J Health Syst Pharm | pmid:7552894 |
Myers AL et al. | Stability of tacrolimus injection diluted in 0.9% sodium chloride injection and stored in Excel bags. | 2016 | Am J Health Syst Pharm | pmid:27919876 |
Grouzmann E et al. | Misleading tacrolimus concentration value in blood taken from a catheter used for tacrolimus administration. | 2008 | Am J Health Syst Pharm | pmid:18216007 |
Kasper RC et al. | Anetoderma arising in cutaneous B-cell lymphoproliferative disease. | 2001 | Am J Dermatopathol | pmid:11285407 |
Breuer K et al. | Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis. | 2005 | Am J Clin Dermatol | pmid:15799678 |
Kalavala M and Dohil MA | Calcineurin inhibitors in pediatric atopic dermatitis: a review of current evidence. | 2011 | Am J Clin Dermatol | pmid:21067248 |
Patel TS et al. | Cancer concerns with topical immunomodulators in atopic dermatitis: overview of data and recommendations to clinicians. | 2007 | Am J Clin Dermatol | pmid:17645374 |
Mertens JS et al. | Morphea and Eosinophilic Fasciitis: An Update. | 2017 | Am J Clin Dermatol | pmid:28303481 |
Wellington K and Noble S | Pimecrolimus: a review of its use in atopic dermatitis. | 2004 | Am J Clin Dermatol | pmid:15663345 |
Ingram JR et al. | Impact of topical calcineurin inhibitors on quality of life in patients with atopic dermatitis. | 2009 | Am J Clin Dermatol | pmid:19489656 |
Reitamo S et al. | Topical noncorticosteroid immunomodulation in the treatment of atopic dermatitis. | 2002 | Am J Clin Dermatol | pmid:12113647 |
Wellington K and Jarvis B | Spotlight on topical pimecrolimus in atopic dermatitis. | 2002 | Am J Clin Dermatol | pmid:12113651 |