tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Oberholzer J et al. | Daclizumab as escape therapy for late acute kidney rejection in the presence of FK506 nephrotoxicity. | 2000 | Transpl. Int. | pmid:10836657 |
| Yoshikawa T et al. | In vivo osteogenic capability of cultured allogeneic bone in porous hydroxyapatite: immunosuppressive and osteogenic potential of FK506 in vivo. | 2000 | J. Bone Miner. Res. | pmid:10841184 |
| Rabinowitz M et al. | Solid-phase/solution-phase combinatorial synthesis of neuroimmunophilin ligands. | 2000 | Bioorg. Med. Chem. Lett. | pmid:10843203 |
| Nasr IS | Topical tacrolimus in dermatology. | 2000 | Clin. Exp. Dermatol. | pmid:10844509 |
| Samsonov D et al. | Enhancement of immune tolerance via induction of NK1.1 positive liver-associated-lymphocytes under immunosuppressive conditions. | 2000 | J. Hepatol. | pmid:10845669 |
| Zhang F et al. | Resistance to Friend murine leukemia virus infection conferred by the Fv-4 gene is recessive but appears dominant from the effect of the immune system. | 2000 | J. Virol. | pmid:10846105 |
| Small bowel transplants in adults and multivisceral transplants in adults and children. | 1999 | Tecnologica MAP Suppl | pmid:10848042 | |
| Tyedmers J et al. | Assembly of heterodimeric luciferase after de novo synthesis of subunits in rabbit reticulocyte lysate involves hsc70 and hsp40 at a post-translational stage. | 2000 | Eur. J. Biochem. | pmid:10848974 |
| Gibson SW et al. | Nutritional immunomodulation leads to enhanced allograft survival in combination with cyclosporine A and rapamycin, but not FK506. | 2000 | Transplantation | pmid:10852592 |
| Konrad T et al. | Regulation of glucose tolerance in patients after liver transplantation: impact of cyclosporin versus tacrolimus therapy. | 2000 | Transplantation | pmid:10852599 |
| Schvarcz R et al. | Interaction between nelfinavir and tacrolimus after orthoptic liver transplantation in a patient coinfected with HIV and hepatitis C virus (HCV). | 2000 | Transplantation | pmid:10852623 |
| Rollins CT et al. | A ligand-reversible dimerization system for controlling protein-protein interactions. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10852943 |
| Florio G et al. | The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils. | 2000 | AIDS | pmid:10853974 |
| Kochi S et al. | Induction of apoptosis in mouse brain capillary endothelial cells by cyclosporin A and tacrolimus. | 2000 | Life Sci. | pmid:10855946 |
| Bultynck G et al. | Effects of the immunosuppressant FK506 on intracellular Ca2+ release and Ca2+ accumulation mechanisms. | 2000 | J. Physiol. (Lond.) | pmid:10856121 |
| Granot E et al. | Monitoring of Epstein-Barr virus serology in children after liver transplant: lack of clinical correlation. | 2000 | Transplant. Proc. | pmid:10856551 |
| Ben-Ari Z et al. | Conversion of liver allograft recipients from cyclosporine A to FK 506 immunosuppressive therapy. | 2000 | Transplant. Proc. | pmid:10856553 |
| Barak S et al. | Alveolar bone height in patients after liver transplantation. | 2000 | Transplant. Proc. | pmid:10856558 |
| Gotsman I et al. | Effect of peripheral immune tolerance on liver-associated lymphocytes expressing NK1.1. | 2000 | Transplant. Proc. | pmid:10856569 |
| Malinowski K et al. | Effect of different anti-rejection regimens on the expression of differentiation and activation markers on the surface of host lymphocytes. | 2000 | Transplant. Proc. | pmid:10856579 |
| McLaughlin GE et al. | Effect of aminophylline on urine flow in children with tacrolimus-induced renal insufficiency. | 2000 | Transplant. Proc. | pmid:10856596 |
| Morelli AE et al. | Microchimerism, donor dendritic cells, and alloimmune reactivity in recipients of Flt3 ligand-mobilized hemopoietic cells: modulation by tacrolimus. | 2000 | J. Immunol. | pmid:10861056 |
| Boubenider S et al. | Interaction between theophylline and tacrolimus in a renal transplant patient. | 2000 | Nephrol. Dial. Transplant. | pmid:10862651 |
| Wu K et al. | The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units. | 2000 | Gene | pmid:10863099 |
| Oike F et al. | A 12-day course of FK506 allows long-term acceptance of semi-identical liver allograft in inbred miniature swine. | 2000 | Transplantation | pmid:10868630 |
| Yamani MH et al. | The impact of routine mycophenolate mofetil drug monitoring on the treatment of cardiac allograft rejection. | 2000 | Transplantation | pmid:10868634 |
| Blakolmer K et al. | Chronic liver allograft rejection in a population treated primarily with tacrolimus as baseline immunosuppression: long-term follow-up and evaluation of features for histopathological staging. | 2000 | Transplantation | pmid:10868635 |
| Neuhaus P et al. | Quadruple tacrolimus-based induction therapy including azathioprine and ALG does not significantly improve outcome after liver transplantation when compared with standard induction with tacrolimus and steroids: results of a prospective, randomized trial. | 2000 | Transplantation | pmid:10868638 |
| Au WY et al. | Tacrolimus (FK 506) induced thrombotic thrombocytopenic purpura after ABO mismatched second liver transplantation: salvage with plasmapheresis and prostacyclin. | 2000 | Haematologica | pmid:10870125 |
| Queille-Roussel C et al. | SDZ ASM 981 is the first non-steroid that suppresses established nickel contact dermatitis elicited by allergen challenge. | 2000 | Contact Derm. | pmid:10871099 |
| Morales JM et al. | Immunosuppression in older renal transplant patients. | 2000 | Drugs Aging | pmid:10874523 |
| Costantini LC and Isacson O | Immunophilin ligands and GDNF enhance neurite branching or elongation from developing dopamine neurons in culture. | 2000 | Exp. Neurol. | pmid:10877916 |
| Castilho RF et al. | FK506 and cyclosporin A enhance the survival of cultured and grafted rat embryonic dopamine neurons. | 2000 | Exp. Neurol. | pmid:10877919 |
| Allison AC | Immunosuppressive drugs: the first 50 years and a glance forward. | 2000 | Immunopharmacology | pmid:10878284 |
| Assmann T et al. | Applications of tacrolimus for the treatment of skin disorders. | 2000 | Immunopharmacology | pmid:10878290 |
| Hamazaki T et al. | [Prophylaxis with FK-506 for graft-versus-host disease after transplantation of bone marrow from unrelated donors]. | 2000 | Rinsho Ketsueki | pmid:10879106 |
| Ben Abraham R et al. | [FK506 (tacrolimus) does not increase hepatic damage due to hypoperfusion]. | 2000 | Harefuah | pmid:10883243 |
| Romano G et al. | Systemic and intratubular effects of cyclosporin-A and tacrolimus on the rat kidney. | 2000 | Eur. J. Pharmacol. | pmid:10884522 |
| Parker EM et al. | Rapamycin, but not FK506 and GPI-1046, increases neurite outgrowth in PC12 cells by inhibiting cell cycle progression. | 2000 | Neuropharmacology | pmid:10884572 |
| Terashima A et al. | Rapamycin and FK506 induce long-term potentiation by pairing stimulation via an intracellular Ca(2+) signaling mechanism in rat hippocampal CA1 neurons. | 2000 | Neuropharmacology | pmid:10884573 |
| Zaman AK | Effects of tacrolimus hydrate (FK-506) on the expression of tissue factor in THP-1 human monocyte cell line. | 2000 | Hokkaido Igaku Zasshi | pmid:10884973 |
| Arthur JM and Shamim S | Interaction of cyclosporine and FK506 with diuretics in transplant patients. | 2000 | Kidney Int. | pmid:10886578 |
| Hooijberg E et al. | NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells. | 2000 | Blood | pmid:10887106 |
| Mori A et al. | Control of IL-5 production by human helper T cells as a treatment for eosinophilic inflammation: comparison of in vitro and in vivo effects between selective and nonselective cytokine synthesis inhibitors. | 2000 | J. Allergy Clin. Immunol. | pmid:10887335 |
| Yue G et al. | The effect of rapamycin on single ENaC channel activity and phosphorylation in A6 cells. | 2000 | Am. J. Physiol., Cell Physiol. | pmid:10898719 |
| Mukerjee N et al. | Caspase-mediated proteolytic activation of calcineurin in thapsigargin-mediated apoptosis in SH-SY5Y neuroblastoma cells. | 2000 | Arch. Biochem. Biophys. | pmid:10898953 |
| Hishinuma S and Ogura K | Ca(2+)/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H(1) receptor-mediated Ca(2+) responses in human U373 MG astrocytoma cells. | 2000 | J. Neurochem. | pmid:10899954 |
| Wang L et al. | Reversal of anticancer drug resistance by macrolide antibiotics in vitro and in vivo. | 2000 | Clin. Exp. Pharmacol. Physiol. | pmid:10901387 |
| Fisher NC et al. | The clinical impact of nephrotoxicity in liver transplantation. | 2000 | Transplantation | pmid:10910259 |
| MacDonald AS | Management strategies for nephrotoxicity. | 2000 | Transplantation | pmid:10910262 |