Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Komura Y et al. | Economic assessment of actual prescription of drugs for treatment of atopic dermatitis: Differences between dermatology and pediatrics in large-scale receipt data. | 2018 | J. Dermatol. | pmid:29168213 |
Akamine Y et al. | A comparison of the effects of CYP3A5 polymorphism on tacrolimus blood concentrations measured by 4 immunoassay methods in renal transplant patients. | 2018 | J Clin Pharm Ther | pmid:28891077 |
Sugahara S et al. | Integrin, alpha9 subunit blockade suppresses collagen-induced arthritis with minimal systemic immunomodulation. | 2018 | Eur. J. Pharmacol. | pmid:29932925 |
Wen L et al. | Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice. | 2018 | Gastroenterology | pmid:29928898 |
Niel O and Bastard P | Artificial intelligence improves estimation of tacrolimus area under the concentration over time curve in renal transplant recipients. | 2018 | Transpl. Int. | pmid:29687486 |
Zhang X et al. | Current progress of tacrolimus dosing in solid organ transplant recipients: Pharmacogenetic considerations. | 2018 | Biomed. Pharmacother. | pmid:29550633 |
Komine N et al. | Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitial fibrosis and long-term graft function in kidney transplant recipients. | 2018 | Int. Immunopharmacol. | pmid:29550576 |
Fu Q et al. | Risk Factors for Acute Rejection After Deceased Donor Kidney Transplantation in China. | 2018 | Transplant. Proc. | pmid:30316380 |
Konno O et al. | Early Outcomes of Living-Donor Kidney Transplantation With Immunosuppression Therapy Induction With Tacrolimus Extended-Release: A Comparison With Cyclosporine. | 2018 | Transplant. Proc. | pmid:30316378 |
Kim JH et al. | Increased Exposure of Tacrolimus by Co-administered Mycophenolate Mofetil: Population Pharmacokinetic Analysis in Healthy Volunteers. | 2018 | Sci Rep | pmid:29374217 |