Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Woodle ES et al. | Corticosteroid withdrawal under tacrolimus primary and rescue therapy in renal transplantation: the Chicago experience. | 1999 | Transplant. Proc. | pmid:10576053 |
Vanrenterghem Y | Vascular rejection with tacrolimus and potential long-term graft outcome. | 1999 | Transplant. Proc. | pmid:10576054 |
Villaverde V et al. | Leg bone pain syndrome in a kidney transplant patient treated with tacrolimus (FK506) | 1999 | Ann. Rheum. Dis. | pmid:10577370 |
Przepiorka D et al. | Practical considerations in the use of tacrolimus for allogeneic marrow transplantation. | 1999 | Bone Marrow Transplant. | pmid:10578154 |
Watanabe Y et al. | The expression of nonmuscle myosin heavy chain in rat renal transplantation. | 1999 | Transplant. Proc. | pmid:10578260 |
Fukushima N et al. | Role of endothelial apoptosis in delayed xenograft rejection in pig-to-baboon cardiac transplantation. | 1999 | Transplant. Proc. | pmid:10578268 |
Moffatt SD and Metcalfe SM | FK 506 versus cyclosporine in combination with anti-CD4/CD8 monoclonal antibodies. | 1999 | Transplant. Proc. | pmid:10578271 |
Sawai T et al. | A successful induction of tolerance by perioperative intrathymic injection in rat "high-responder" heart transplantation. | 1999 | Transplant. Proc. | pmid:10578275 |
Uchida H et al. | Chronopharmacology of tacrolimus in rats: toxicity and efficacy in a mouse-to-rat intestinal transplant model and its pharmacokinetic profile. | 1999 | Transplant. Proc. | pmid:10578276 |
Moffatt SD et al. | Comparative efficacy of liposomal FK 506 with FK 506 (tacrolimus) with and without anti-CD4/CD8 monoclonal antibodies. | 1999 | Transplant. Proc. | pmid:10578277 |
Hampel G et al. | Different effects of cyclosporine and tacrolimus on the activation of mesangial metalloproteinases and their inhibitors. | 1999 | Transplant. Proc. | pmid:10578279 |
Ishibashi M et al. | Elimination of the adverse effects of tacrolimus-based induction therapy by a 5-day exposure of optimal steady-state blood concentration in renal transplant patients in the early postoperative period. | 1999 | Transplant. Proc. | pmid:10578281 |
Tojimbara T et al. | Oral vs intravenous tacrolimus-based induction therapy in renal transplantation. | 1999 | Transplant. Proc. | pmid:10578282 |
Hairhara Y et al. | Effect of fluconazole on blood levels of tacrolimus. | 1999 | Transplant. Proc. | pmid:10578284 |
Tamura A et al. | Combination effect of tacrolimus and FTY720 in liver transplantation in rats. | 1999 | Transplant. Proc. | pmid:10578290 |
Kita J et al. | Effects of tacrolimus on small and large bowel anastomoses in the rat. | 1999 | Transplant. Proc. | pmid:10578292 |
Azuma T et al. | Study of graft-infiltrating cells in the rat small bowel allograft using low-dose FK 506. | 1999 | Transplant. Proc. | pmid:10578293 |
Antoniou EA et al. | Effect of donor-specific transfusion in combination with FK 506 in rat cardiac allotransplantation. | 1999 | Transplant. Proc. | pmid:10578296 |
Uchida H et al. | Experimental intestinal transplantation using mouse fetal intestine in the rat: combination effect of FK 506 with cyclophosphamide. | 1999 | Transplant. Proc. | pmid:10578297 |
Manu MA et al. | Tacrolimus rescue for resistant rejection, chronic rejection, and immunoglobulin A nephropathy of renal allografts under primary cyclosporine A immunosuppression. | 1999 | Transplant. Proc. | pmid:10578313 |