Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Gabe SM et al. | The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans. | 1998 | Gastroenterology | pmid:9649460 |
Gruessner RW et al. | Suggested guidelines for the use of tacrolimus in pancreas/kidney transplantation. | 1998 | Clin Transplant | pmid:9642520 |
Kuwata T et al. | A role of calcineurin in coreceptor regulation during differentiation of Cd4+Cd8+ T cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9642110 |
Murray M et al. | Comparison of tacrolimus absorption in transplant patients receiving continuous versus interrupted enteral nutritional feeding. | 1998 | Ann Pharmacother | pmid:9640479 |
Morris-Stiff G and Jurewicz WA | Single centre experience with mycophenolate mofetil for refractory rejection in cadaveric renal transplantation. | 1998 | Transpl. Int. | pmid:9638849 |
Takahara S et al. | A comparative study of FK506 granules and capsules in renal transplant recipients. | 1998 | Transpl. Int. | pmid:9638846 |
Abraham RT | Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling. | 1998 | Curr. Opin. Immunol. | pmid:9638370 |
Baldari CT et al. | NF-AT-luciferase reporter T cell lines as tools to screen immunosuppressive drugs. | 1998 | Biologicals | pmid:9637743 |
Resch K and Szamel M | Molecular mechanisms of the immunosuppressive action of cyclosporin A. | 1997 Sep-Oct | Int. J. Immunopharmacol. | pmid:9637358 |
Schneeberger H et al. | Tacrolimus as a primary immunosuppressive therapy in cadaveric renal transplantation: five years' experience at a single center. | 1998 | Transplant. Proc. | pmid:9636642 |
Gerber DA et al. | Immunosuppressive agents: recent developments in molecular action and clinical application. | 1998 | Transplant. Proc. | pmid:9636637 |
Goulet O et al. | Small bowel transplantation alone or with the liver in children: changes by using FK506. | 1998 | Transplant. Proc. | pmid:9636636 |
Stratta RJ | Late acute rejection episodes after vascularized pancreas transplantation. | 1998 | Transplant. Proc. | pmid:9636633 |
Gruessner RW | Antibody induction therapy in pancreas transplantation. | 1998 | Transplant. Proc. | pmid:9636632 |
Burke GW et al. | Use of tacrolimus and mycophenolate mofetil for pancreas-kidney transplantation with or without OKT3 induction. | 1998 | Transplant. Proc. | pmid:9636627 |
Peddi VR et al. | Long-term kidney and pancreas function with tacrolimus immunosuppression following simultaneous kidney and pancreas transplantation. | 1998 | Transplant. Proc. | pmid:9636626 |
Bruce DS et al. | Tacrolimus/mycophenolate provides superior immunosuppression relative to neoral/mycophenolate in synchronous pancreas-kidney transplantation. | 1998 | Transplant. Proc. | pmid:9636625 |
Ciancio G et al. | Use of intravenous tacrolimus to reverse vascular rejection in kidney and simultaneous kidney-pancreas transplantation. | 1998 | Transplant. Proc. | pmid:9636624 |
Schulz T et al. | Tacrolimus/mycophenolate mofetil/steroid-based immunosuppression after pancreas-kidney transplantation with single shot antithymocyte globulin. | 1998 | Transplant. Proc. | pmid:9636623 |
Walker S et al. | Clinical use and bioavailability of tacrolimus in heart-lung and double lung transplant recipients with cystic fibrosis. | 1998 | Transplant. Proc. | pmid:9636618 |