|
The discovery of FK-506 and U.S. development. |
1991 |
Nephrol News Issues |
pmid:1720512
|
Zheng B et al. |
Effects of the new and highly active immunosuppressant, rapamycin, on lymphoid tissues and cells in vivo. |
1991 |
Transplant. Proc. |
pmid:1703717
|
Mieles L et al. |
Interaction between FK506 and clotrimazole in a liver transplant recipient. |
1991 |
Transplantation |
pmid:1721250
|
Yabuuchi H et al. |
Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin. |
1991 |
Transplant. Proc. |
pmid:1703718
|
|
First International Congress on FK 506. August 21-24, 1991, Pittsburgh, PA. |
1991 |
Transplant. Proc. |
pmid:1721253
|
Goto T et al. |
FK 506: historical perspectives. |
1991 |
Transplant. Proc. |
pmid:1721254
|
Farghali H et al. |
Effect of FK 506 chronic administration on bromosulphthalein hepatic excretion in rats. |
1991 |
Transplant. Proc. |
pmid:1721283
|
Farghali H et al. |
A biochemical and 31P-NMR investigation of the effect of FK 506 and cyclosporine pretreatment on immobilized hepatocytes perifused with ethanol. |
1991 |
Transplant. Proc. |
pmid:1721284
|
Farghali H et al. |
FK 506 modulates D-galactosamine-induced hepatitis in rats. |
1991 |
Transplant. Proc. |
pmid:1721285
|
Müller MK et al. |
Inhibition of insulin release by FK 506 and its prevention by rioprostil, a stable prostaglandin E1 analogue. |
1991 |
Transplant. Proc. |
pmid:1721286
|
Matsuura T et al. |
Beneficial immunosuppressive effect of combined use of FK 506 and cyclosporine assessed by proliferative responses of cloned human T cells. |
1991 |
Transplant. Proc. |
pmid:1721316
|
Jiang H et al. |
Combined immunosuppressive effect of FK 506 and other immunosuppressive agents on PHA- and CD3-stimulated human lymphocyte proliferation in vitro. |
1991 |
Transplant. Proc. |
pmid:1721317
|
Yagihashi A et al. |
The effect of FK 506 on peripheral blood T-lymphocyte subsets in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721318
|
Woo J et al. |
Effects of FK 506, mycophenolic acid, and bredinin on OKT-3-, PMA-, and alloantigen-induced activation molecule expression on cultured CD4+ and CD8+ human lymphocytes. |
1991 |
Transplant. Proc. |
pmid:1721319
|
Jain AB et al. |
Correlation of rejection episodes with FK 506 dosage, FK 506 level, and steroids following primary orthotopic liver transplant. |
1991 |
Transplant. Proc. |
pmid:1721347
|
Takaya S et al. |
Retransplantation of liver: a comparison of FK 506- and cyclosporine-treated patients. |
1991 |
Transplant. Proc. |
pmid:1721348
|
Morel P et al. |
Liver retransplantation in adults: overall results and determinant factors affecting the outcome. |
1991 |
Transplant. Proc. |
pmid:1721349
|
Felser I et al. |
Changes in quality of life following conversion from CyA to FK 506 in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721350
|
Schreiber SL |
Chemistry and biology of the immunophilins and their immunosuppressive ligands. |
1991 |
Science |
pmid:1702904
|
Prasad SJ et al. |
In vitro effects of cyclosporine and FK 506 on the renal cortex. |
1991 |
Transplant. Proc. |
pmid:1721380
|
Kusne S et al. |
Early infections in kidney transplant recipients under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703364
|
Yamada K et al. |
Short-term FK 506-induced morphological changes in rat kidneys. |
1991 |
Transplant. Proc. |
pmid:1721381
|
Moutabarrik A et al. |
FK 506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells and tubular cell toxicity in vitro. |
1991 |
Transplant. Proc. |
pmid:1721382
|
Moutabarrik A et al. |
In vitro FK 506 kidney tubular cell toxicity. |
1991 |
Transplant. Proc. |
pmid:1721383
|
Tze WJ et al. |
Long-term survival of islet allografts in diabetic rats treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721411
|
Wang X et al. |
Intraportal FK 506 improves intrahepatic islet allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721412
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721413
|
Yamashita T et al. |
Prolongation of pancreaticoduodenal allograft survival in rats by treatment with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721414
|
Bierer BE et al. |
The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation. |
1991 |
Eur. J. Immunol. |
pmid:1705513
|
Heitman J et al. |
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1705713
|
Goebl MG |
The peptidyl-prolyl isomerase, FK506-binding protein, is most likely the 12 kd endogenous inhibitor 2 of protein kinase C. |
1991 |
Cell |
pmid:1706222
|
Yokomise H et al. |
Immunosuppressive effects of FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721442
|
Hasegawa S et al. |
FK 506 and cyclosporine: effects and side effects in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721443
|
Wada H et al. |
Dose response to FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721444
|
Lin CY et al. |
Effects of FK 506 on the biochemical markers in canine lung allograft rejection. |
1991 |
Transplant. Proc. |
pmid:1721445
|
Francavilla A et al. |
Studies on mechanisms of augmentation of liver regeneration by cyclosporine and FK 506. |
1991 |
Hepatology |
pmid:1712337
|
Aoki H |
[FK 506, a new immunosuppressant produced by a Streptomyces]. |
1991 |
Nippon Rinsho |
pmid:1712403
|
Hultsch T et al. |
Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1712484
|
Miyahara H et al. |
Comparative studies of the effects of FK506 and cyclosporin A on passively transferred collagen-induced arthritis in rats. |
1991 |
Clin. Immunol. Immunopathol. |
pmid:1712688
|
Weaver JL et al. |
Comparison of the in vitro and biophysical effects of cyclosporine A, FK-506, and mycophenolic acid on human peripheral blood lymphocytes. |
1991 |
Immunopharmacol Immunotoxicol |
pmid:1723084
|
DiLella AG and Craig RJ |
Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains. |
1991 |
Biochemistry |
pmid:1716149
|
Burres NS et al. |
Dunaimycins, a new complex of spiroketal 24-membered macrolides with immunosuppressive activity. III. Immunosuppressive activities of dunaimycins. |
1991 |
J. Antibiot. |
pmid:1723403
|
Nielsen JB et al. |
Biosynthesis of the immunosuppressant immunomycin: the enzymology of pipecolate incorporation. |
1991 |
Biochemistry |
pmid:2043618
|
McKeon F |
When worlds collide: immunosuppressants meet protein phosphatases. |
1991 |
Cell |
pmid:1716181
|
Petros AM et al. |
NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding. |
1991 |
J. Med. Chem. |
pmid:1716684
|
|
FK 506--an investigational immunosuppressant. |
1991 |
Med Lett Drugs Ther |
pmid:1716722
|
Henderson DJ et al. |
Comparison of the effects of FK-506, cyclosporin A and rapamycin on IL-2 production. |
1991 |
Immunology |
pmid:1715317
|
DeFranco AL |
Signal transduction. Immunosuppressants at work. |
1991 |
Nature |
pmid:1715515
|
Flanagan WM et al. |
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. |
1991 |
Nature |
pmid:1715516
|
McWhinnie DL and Morris PJ |
Combination drug therapies for immunosuppression in transplantation. |
1991 |
Ann. Acad. Med. Singap. |
pmid:1724724
|