Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Whalen HR et al. | High Intrapatient Tacrolimus Variability Is Associated With Worse Outcomes in Renal Transplantation Using a Low-Dose Tacrolimus Immunosuppressive Regime. | 2017 | Transplantation | pmid:26950724 |
de Fijter JW et al. | Early Conversion From Calcineurin Inhibitor- to Everolimus-Based Therapy Following Kidney Transplantation: Results of the Randomized ELEVATE Trial. | 2017 | Am. J. Transplant. | pmid:28027625 |
Kabat-Koperska J et al. | Birth defects in juvenile Wistar rats after exposure to immunosuppressive drugs during pregnancy. | 2017 | Histol. Histopathol. | pmid:27097725 |
Ueno P et al. | Wound Healing Complications in Kidney Transplant Recipients Receiving Everolimus. | 2017 | Transplantation | pmid:27490418 |
Li Y et al. | [Study on the Effect of Immunosuppressive Agent FK506 on Growth and Migration of Lung Cancer Cell]. | 2017 | Zhongguo Fei Ai Za Zhi | pmid:28738959 |
Nakamura Y et al. | Successful Treatment of Behçet's Disease Associated with Acute Myeloid Leukemia with Myelodysplasia-related Changes Using Azacitidine and Tacrolimus before Allogeneic Hematopoietic Stem Cell Transplantation. | 2017 | Intern. Med. | pmid:28502936 |
Sanghavi K et al. | Genotype-guided tacrolimus dosing in African-American kidney transplant recipients. | 2017 | Pharmacogenomics J. | pmid:26667830 |
Heemann U and Viklicky O | Is trough level variability the new tool for identifying patients at risk for rejection after transplantation? | 2017 | Nephrol. Dial. Transplant. | pmid:28186537 |
Størset E et al. | Response to: 'Response to: Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'. | 2017 | Br J Clin Pharmacol | pmid:28374426 |
Lawrance IC et al. | Efficacy of Rectal Tacrolimus for Induction Therapy in Patients With Resistant Ulcerative Proctitis. | 2017 | Clin. Gastroenterol. Hepatol. | pmid:28286194 |
Morita M et al. | The onset risk of carcinoma in patients continuing tacrolimus topical treatment for oral lichen planus: a case report. | 2017 | Odontology | pmid:27368962 |
Shimizu S et al. | Reduction of FR900525 using an S-(2-aminoethyl) l-cysteine-resistant mutant. | 2017 | J. Biosci. Bioeng. | pmid:28185832 |
Chung BH et al. | Suppressive Effect of 1α,25-Dihydroxyvitamin D3 on Th17-Immune Responses in Kidney Transplant Recipients With Tacrolimus-Based Immunosuppression. | 2017 | Transplantation | pmid:28107277 |
Ak K et al. | Tacrolimus-Eluting Suture Inhibits Neointimal Hyperplasia: An Experimental In Vivo Study in Rats. | 2017 | Eur J Vasc Endovasc Surg | pmid:28065442 |
MartÃn-Fernández M et al. | Effects of Cyclosporine, Tacrolimus, and Rapamycin on Osteoblasts. | 2017 | Transplant. Proc. | pmid:29149986 |
Ivulich S et al. | Clinical Challenges of Tacrolimus for Maintenance Immunosuppression Post-Lung Transplantation. | 2017 | Transplant. Proc. | pmid:29149976 |
Khan SA et al. | Improvement in baroreflex control of renal sympathetic nerve activity in obese Sprague Dawley rats following immunosuppression. | 2017 | Acta Physiol (Oxf) | pmid:28456134 |
Wan T et al. | Dual roles of TPGS based microemulsion for tacrolimus: Enhancing the percutaneous delivery and anti-psoriatic efficacy. | 2017 | Int J Pharm | pmid:28629978 |
Tremblay S and Alloway RR | Clinical Evaluation of Modified Release and Immediate Release Tacrolimus Formulations. | 2017 | AAPS J | pmid:28717926 |
Burbulla LF et al. | Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. | 2017 | Science | pmid:28882997 |