| MeSH term | MeSH ID | Detail |
|---|---|---|
| Intracranial Thrombosis | D020767 | 2 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
| Nervous System Autoimmune Disease, Experimental | D020721 | 3 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Brain Infarction | D020520 | 17 associated lipids |
| Peroneal Neuropathies | D020427 | 1 associated lipids |
| Sciatic Neuropathy | D020426 | 13 associated lipids |
| Osteoarthritis, Knee | D020370 | 13 associated lipids |
| Paraneoplastic Syndromes, Nervous System | D020361 | 1 associated lipids |
| Hypertensive Encephalopathy | D020343 | 1 associated lipids |
| Migraine with Aura | D020325 | 1 associated lipids |
| Autoimmune Diseases of the Nervous System | D020274 | 1 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Ventricular Remodeling | D020257 | 28 associated lipids |
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Optic Nerve Injuries | D020221 | 4 associated lipids |
| Facial Nerve Injuries | D020220 | 1 associated lipids |
| Trauma, Nervous System | D020196 | 2 associated lipids |
| Nocturnal Myoclonus Syndrome | D020189 | 1 associated lipids |
| Sleep Apnea, Central | D020182 | 1 associated lipids |
| Citrullinemia | D020159 | 1 associated lipids |
| Hepatopulmonary Syndrome | D020065 | 1 associated lipids |
| Epstein-Barr Virus Infections | D020031 | 3 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Miller Fisher Syndrome | D019846 | 1 associated lipids |
| Hepatitis C, Chronic | D019698 | 12 associated lipids |
| Hepatitis B, Chronic | D019694 | 4 associated lipids |
| Hepatitis, Autoimmune | D019693 | 1 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Intracranial Hypertension | D019586 | 4 associated lipids |
| Dermatitis, Perioral | D019557 | 4 associated lipids |
| Pouchitis | D019449 | 3 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
| Oral Ulcer | D019226 | 1 associated lipids |
| Gingival Overgrowth | D019214 | 7 associated lipids |
| Fasciitis, Necrotizing | D019115 | 1 associated lipids |
| Postoperative Hemorrhage | D019106 | 7 associated lipids |
| Multiple Endocrine Neoplasia Type 2a | D018813 | 1 associated lipids |
| Anemia, Iron-Deficiency | D018798 | 6 associated lipids |
| Encephalitis, Viral | D018792 | 3 associated lipids |
| Hypoplastic Left Heart Syndrome | D018636 | 1 associated lipids |
| Cryptogenic Organizing Pneumonia | D018549 | 3 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Lichen Sclerosus et Atrophicus | D018459 | 2 associated lipids |
| Vasculitis, Leukocytoclastic, Cutaneous | D018366 | 5 associated lipids |
| Hutchinson's Melanotic Freckle | D018327 | 2 associated lipids |
| Angiofibroma | D018322 | 2 associated lipids |
| Cervical Intraepithelial Neoplasia | D018290 | 1 associated lipids |
| Seminoma | D018239 | 2 associated lipids |
| Smooth Muscle Tumor | D018235 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tang S and Lai KN | Quiz page. Posttransplantation lymphoproliferative disorder (PTLD) involving the brain and the allograft. | 2005 | Am. J. Kidney Dis. | pmid:15806458 |
| Rao PS | Nephrotic syndrome in patients with peripheral blood stem cell transplant. | 2005 | Am. J. Kidney Dis. | pmid:15806483 |
| Choudhry S et al. | Efficacy and safety of tacrolimus versus cyclosporine in children with steroid-resistant nephrotic syndrome: a randomized controlled trial. | 2009 | Am. J. Kidney Dis. | pmid:19268410 |
| Birdwell KA et al. | Decreased antibody response to influenza vaccination in kidney transplant recipients: a prospective cohort study. | 2009 | Am. J. Kidney Dis. | pmid:19185404 |
| Haas M et al. | Smooth muscle-specific actin levels in the urine of renal transplant recipients: correlation with cyclosporine or tacrolimus nephrotoxicity. | 1999 | Am. J. Kidney Dis. | pmid:10401019 |
| Wong TY et al. | Parvovirus B19 infection causing red cell aplasia in renal transplantation on tacrolimus. | 1999 | Am. J. Kidney Dis. | pmid:10585325 |
| Hricik DE | Safety and efficacy of TOR inhibitors and other immunosuppressive regimens in African-American renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11583939 |
| Pescovitz MD and Govani M | Sirolimus and mycophenolate mofetil for calcineurin-free immunosuppression in renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11583940 |
| Tang S et al. | Use of tacrolimus in steroid- and cyclophosphamide-resistant minimal change nephrotic syndrome. | 2003 | Am. J. Kidney Dis. | pmid:14582073 |
| Pham PT et al. | Cyclosporine and tacrolimus-associated thrombotic microangiopathy. | 2000 | Am. J. Kidney Dis. | pmid:11007689 |
| Revelo MP et al. | A 14-year-old boy with kidney allograft failure in the first month after transplantation. | 2000 | Am. J. Kidney Dis. | pmid:11007695 |
| Lien YH and Bracamonte ER | Quiz page February 2011: acute kidney injury, graft pain, and subtherapeutic levels of tacrolimus. | 2011 | Am. J. Kidney Dis. | pmid:21251536 |
| Pavan M et al. | Altered bioavailability of tacrolimus following intravenous administration of tigecycline. | 2011 | Am. J. Kidney Dis. | pmid:21251548 |
| Vischini G et al. | Increased plasma levels of tacrolimus after ingestion of green tea. | 2011 | Am. J. Kidney Dis. | pmid:21787983 |
| van Duijnhoven EM et al. | A late episode of post-transplant diabetes mellitus during active hepatitis C infection in a renal allograft recipient using tacrolimus. | 2002 | Am. J. Kidney Dis. | pmid:12087579 |
| Moes AD et al. | Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial. | 2017 | Am. J. Kidney Dis. | pmid:28259499 |
| Wong KM et al. | Abbreviated tacrolimus area-under-the-curve monitoring for renal transplant recipients. | 2000 | Am. J. Kidney Dis. | pmid:10739787 |
| Böhmig GA et al. | Role of humoral immune reactions as target for antirejection therapy in recipients of a spousal-donor kidney graft. | 2000 | Am. J. Kidney Dis. | pmid:10739788 |
| Starzl TE et al. | Tacrolimus (FK506) and the pharmaceutical/academic/regulatory gauntlet. | 1998 | Am. J. Kidney Dis. | pmid:9631858 |
| Li X et al. | Tacrolimus therapy in adults with steroid- and cyclophosphamide-resistant nephrotic syndrome and normal or mildly reduced GFR. | 2009 | Am. J. Kidney Dis. | pmid:19406543 |
| Al-Awwa IA et al. | Importance of allograft biopsy in renal transplant recipients: correlation between clinical and histological diagnosis. | 1998 | Am. J. Kidney Dis. | pmid:9631859 |
| Lum EL et al. | Acute Kidney Allograft Rejection Precipitated by Lenalidomide Treatment for Multiple Myeloma. | 2017 | Am. J. Kidney Dis. | pmid:28189378 |
| Neylan JF et al. | Assessment of the frequency and costs of posttransplantation hospitalizations in patients receiving tacrolimus versus cyclosporine. | 1998 | Am. J. Kidney Dis. | pmid:9820446 |
| Chen W et al. | Short-term outcomes of induction therapy with tacrolimus versus cyclophosphamide for active lupus nephritis: A multicenter randomized clinical trial. | 2011 | Am. J. Kidney Dis. | pmid:21177013 |
| First MR | Renal transplantation for the nephrologist: new immunosuppressive drugs. | 1992 | Am. J. Kidney Dis. | pmid:1371201 |
| Mertz D et al. | Drug-drug interaction in a kidney transplant recipient receiving HIV salvage therapy and tacrolimus. | 2009 | Am. J. Kidney Dis. | pmid:19346040 |
| Israni A et al. | Conversion to tacrolimus for the treatment of cyclosporine-associated nephrotoxicity in heart transplant recipients. | 2002 | Am. J. Kidney Dis. | pmid:11877596 |
| Soi V et al. | Altered mental status in a kidney transplant recipient receiving tacrolimus. | 2008 | Am. J. Kidney Dis. | pmid:18155524 |
| Mathis AS and Friedman GS | Coadministration of digoxin with itraconazole in renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11157404 |
| Tsinalis D et al. | Acute renal failure in a renal allograft recipient treated with intravenous immunoglobulin. | 2002 | Am. J. Kidney Dis. | pmid:12200824 |
| Asif A et al. | Peritoneoscopic placement of peritoneal dialysis catheter and bowel perforation: experience of an interventional nephrology program. | 2003 | Am. J. Kidney Dis. | pmid:14655200 |
| Grinyó JM et al. | Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial. | 2017 | Am. J. Kidney Dis. | pmid:27889299 |
| Lien YH | Top 10 Things Primary Care Physicians Should Know About Maintenance Immunosuppression for Transplant Recipients. | 2016 | Am. J. Med. | pmid:26714210 |
| Bar J et al. | Is immunosuppression therapy in renal allograft recipients teratogenic? A single-center experience. | 2003 | Am. J. Med. Genet. A | pmid:12476448 |
| Perez-Aytes A et al. | In utero exposure to mycophenolate mofetil: a characteristic phenotype? | 2008 | Am. J. Med. Genet. A | pmid:18074358 |
| Chen W et al. | Outcomes of tacrolimus therapy in adults with refractory membranous nephrotic syndrome: a prospective, multicenter clinical trial. | 2013 | Am. J. Med. Sci. | pmid:22627258 |
| Hsu MS et al. | Clinical features and outcome of tuberculosis in solid organ transplant recipients. | 2007 | Am. J. Med. Sci. | pmid:17700199 |
| Ocampo-Garza J et al. | Acquired Hyperpigmentation and Cicatricial Alopecia. | 2016 | Am. J. Med. Sci. | pmid:27524226 |
| Chen M et al. | Tacrolimus combined with corticosteroids in treatment of nephrotic idiopathic membranous nephropathy: a multicenter randomized controlled trial. | 2010 | Am. J. Med. Sci. | pmid:20220333 |
| Esposito C et al. | Sirolimus prevents short-term renal changes induced by ischemia-reperfusion injury in rats. | 2011 | Am. J. Nephrol. | pmid:21358177 |
| Ren H et al. | Tacrolimus versus cyclophosphamide in steroid-dependent or steroid-resistant focal segmental glomerulosclerosis: a randomized controlled trial. | 2013 | Am. J. Nephrol. | pmid:23343906 |
| Araujo LP et al. | Interaction of the anti-inflammatory annexin A1 protein and tacrolimus immunosuppressant in the renal function of rats. | 2010 | Am. J. Nephrol. | pmid:20484890 |
| Fourtounas C et al. | Different immunosuppressive combinations on T-cell regulation in renal transplant recipients. | 2010 | Am. J. Nephrol. | pmid:20484893 |
| Tsipotis E et al. | Bioavailability, Efficacy and Safety of Generic Immunosuppressive Drugs for Kidney Transplantation: A Systematic Review and Meta-Analysis. | 2016 | Am. J. Nephrol. | pmid:27576318 |
| Taber DJ et al. | Significant racial differences in the key factors associated with early graft loss in kidney transplant recipients. | 2014 | Am. J. Nephrol. | pmid:24969370 |
| Zhang Q et al. | Tacrolimus improves the proteinuria remission in patients with refractory IgA nephropathy. | 2012 | Am. J. Nephrol. | pmid:22456060 |
| Soubhia RM et al. | Tacrolimus and nonsteroidal anti-inflammatory drugs: an association to be avoided. | 2005 Jul-Aug | Am. J. Nephrol. | pmid:15976495 |
| Dai DS et al. | Protective Effect of Salvia Przewalskii Extract on Puromycin-Induced Podocyte Injury. | 2015 | Am. J. Nephrol. | pmid:26439819 |
| Jin J et al. | Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway. | 2016 | Am. J. Nephrol. | pmid:27174564 |
| Bagnis C et al. | Comparative acute nephrotoxicity of FK-506 and ciclosporin in an isolated in situ autoperfused rat kidney model. | 1997 | Am. J. Nephrol. | pmid:9057948 |