Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Melk A et al. | P-glycoprotein expression in patients before and after kidney transplantation. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083115 |
Undre NA et al. | Low systemic exposure to tacrolimus correlates with acute rejection. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083114 |
Miller J | Tacrolimus and mycophenolate mofetil in renal transplant recipients: one year results of a multicenter, randomized dose ranging trial. FK506/MMF Dose-Ranging Kidney Transplant Study Group. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083106 |
Reichenspurner H et al. | Tacrolimus-based immunosuppressive protocols in lung transplantation. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083062 |
Bennett WM | Renal complications after heart transplantation. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083019 |
Meiser BM et al. | The efficacy of the combination of tacrolimus and mycophenolate mofetil for prevention of acute myocardial rejection is dependent on routine monitoring of mycophenolic acid trough acid levels. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083018 |
Scott JS et al. | Tacrolimus: a cause of hypertrophic cardiomyopathy in pediatric heart transplant recipients? | 1999 Feb-Mar | Transplant. Proc. | pmid:10083017 |
Ghasemian SR et al. | Tacrolimus vs Neoral in renal and renal/pancreas transplantation. | 1999 | Clin Transplant | pmid:10081648 |
Kleindienst R et al. | Bronchiolitis obliterans organizing pneumonia associated with Pneumocystis carinii infection in a liver transplant patient receiving tacrolimus. | 1999 | Clin Transplant | pmid:10081638 |
Takada S et al. | Effect of hepatocyte growth factor on tacrolimus-induced nephrotoxicity in spontaneously hypertensive rats. | 1999 | Transpl. Int. | pmid:10080403 |
Kaplan B et al. | Low bioavailability of cyclosporine microemulsion and tacrolimus in a small bowel transplant recipient: possible relationship to intestinal P-glycoprotein activity. | 1999 | Transplantation | pmid:10075604 |
Shapiro R et al. | Pediatric renal transplantation under tacrolimus-based immunosuppression. | 1999 | Transplantation | pmid:10075598 |
Jordan ML et al. | Long-term results of pancreas transplantation under tacrolius immunosuppression. | 1999 | Transplantation | pmid:10075592 |
Trajković V et al. | Cyclosporin A suppresses the induction of nitric oxide synthesis in interferon-gamma-treated L929 fibroblasts. | 1999 | Scand. J. Immunol. | pmid:10075015 |
Sigalet DL et al. | Effect of combined immunosuppressive drug therapy on small intestinal nutrient transport in the rat. | 1999 | Clin. Biochem. | pmid:10074892 |
Reyes J and Mazariegos GV | Pediatric transplantation. | 1999 | Surg. Clin. North Am. | pmid:10073188 |
Jain A et al. | Immunosuppressive therapy. | 1999 | Surg. Clin. North Am. | pmid:10073182 |
Mitsumoto Y et al. | FK506 with portal decompression exerts beneficial effects following extended hepatectomy in dogs. | 1999 | Eur Surg Res | pmid:10072610 |
Jain AB et al. | Primary adult liver transplantation under tacrolimus: more than 90 months actual follow-up survival and adverse events. | 1999 | Liver Transpl Surg | pmid:10071354 |
Jain AB et al. | Effect of t-tube clamping on the pharmacokinetics of mycophenolic acid in liver transplant patients on oral therapy of mycophenolate mofetil. | 1999 | Liver Transpl Surg | pmid:10071348 |