Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lipozencić J | Pimecrolimus--a safe and effective local immunomodulator in the treatment of inflammatory skin diseases. | 2005 | Acta Dermatovenerol Croat | pmid:15788149 |
Jedlicková H et al. | Granuloma faciale successfully treated with topical tacrolimus: a case report. | 2008 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:18454269 |
Thaçi D and Salgo R | The topical calcineurin inhibitor pimecrolimus in atopic dermatitis: a safety update. | 2007 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:17992459 |
Vukićević J et al. | Unilateral multiple lichen striatus treated with tacrolimus ointment: a case report. | 2009 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:19350187 |
Quist SR et al. | Effects of Topical Tacrolimus and Polyunsaturated Fatty Acids on In Vivo Release of Eicosanoids in Atopic Dermatitis During Dermal Microdialysis. | 2016 | Acta Derm. Venereol. | pmid:26911315 |
Hartmann A et al. | Treatment of generalised vitiligo with tacrolimus 0.1% ointment vs. UVB intense pulsed light phototherapy: a pilot study. | 2014 | Acta Derm. Venereol. | pmid:24473666 |
Murota H et al. | Olopatadine hydrochloride decreases tissue interleukin-31 levels in an atopic dermatitis mouse model. | 2014 | Acta Derm. Venereol. | pmid:23817562 |
Larsen CG and Thyssen JP | Pustular penile pyoderma gangrenosum successfully treated with topical tacrolimus ointment. | 2012 | Acta Derm. Venereol. | pmid:21681352 |
Fukamachi S et al. | Therapeutic effectiveness of various treatments for eosinophilic pustular folliculitis. | 2009 | Acta Derm. Venereol. | pmid:19326000 |
Jacobs F et al. | New approach in combined therapy of perifolliculitis capitis abscedens et suffodiens. | 2011 | Acta Derm. Venereol. | pmid:21681358 |