tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dury S et al. | Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study. | 2015 | BMC Pulm Med | pmid:26545860 |
| Kwon M et al. | Bioequivalence of tacrolimus formulations with different dynamic solubility and in-vitro dissolution profiles. | 2015 | Arch. Pharm. Res. | pmid:24627339 |
| TuÄŸcu M et al. | Tacrolimus-Induced Diabetic Ketoacidosis and Effect of Switching to Everolimus: A Case Report. | 2015 | Transplant. Proc. | pmid:26093759 |
| Tang T et al. | Roles of the tacrolimus-dependent transcription factor IRF4 in acute rejection after liver transplantation. | 2015 | Int. Immunopharmacol. | pmid:26093273 |
| Aktürk S et al. | Pregnancy After Kidney Transplantation: Outcomes, Tacrolimus Doses, and Trough Levels. | 2015 | Transplant. Proc. | pmid:26093738 |
| Rahman S et al. | Nordihydroguiaretic acid attenuates skin tumorigenesis in Swiss albino mice with the condition of topical co-administration of an immunosuppressant. | 2015 | Chem. Biol. Interact. | pmid:25770929 |
| Yano S et al. | Pharmacokinetics for once-daily modified release formulation of tacrolimus hydrate in unrelated hematopoietic stem cell transplantation. | 2015 | Ann. Hematol. | pmid:25325985 |
| Rossetto AM et al. | The full electron structure of the FKBP12/FK506 complex. | 2015 | J. Biomol. Struct. Dyn. | pmid:24471694 |
| Li DW et al. | Risk factors for new onset diabetes mellitus after liver transplantation: A meta-analysis. | 2015 | World J. Gastroenterol. | pmid:26034369 |
| Miura M et al. | Tacrolimus reduction with everolimus addition for calcineurin inhibitor-induced arteriolopathy in kidney allografts. | 2015 | Nephrology (Carlton) | pmid:26031588 |
| Ma R et al. | FK506 ameliorates podocyte injury in type 2 diabetic nephropathy by down-regulating TRPC6 and NFAT expression. | 2015 | Int J Clin Exp Pathol | pmid:26823720 |
| Kaieda S et al. | Successful treatment of macrophage activation syndrome in a patient with dermatomyositis by combination with immunosuppressive therapy and plasmapheresis. | 2015 | Mod Rheumatol | pmid:24252010 |
| Kawaoka T et al. | Two patients treated with simeprevir plus pegylated-interferon and ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation: case report. | 2015 | Transplant. Proc. | pmid:25891736 |
| Kim YT et al. | Co-treatment effect of pulsed electromagnetic field (PEMF) with human dental pulp stromal cells and FK506 on the regeneration of crush injured rat sciatic nerve. | 2015 | Int. J. Neurosci. | pmid:25271799 |
| Ichimaru N et al. | Risk factors and incidence for lipid abnormalities in kidney transplant patients. | 2015 | Transplant. Proc. | pmid:25891708 |
| Kogiso T et al. | Mycophenolate mofetil may induce prolonged severe anemia during pegylated-interferon/ribavirin/simeprevir therapy in liver transplant recipients. | 2015 | Clin J Gastroenterol | pmid:25963122 |
| Bruckmueller H et al. | Which Genetic Determinants Should be Considered for Tacrolimus Dose Optimization in Kidney Transplantation? A Combined Analysis of Genes Affecting the CYP3A Locus. | 2015 | Ther Drug Monit | pmid:25271728 |
| Shu WY et al. | Pharmacogenomics and personalized medicine: a review focused on their application in the Chinese population. | 2015 | Acta Pharmacol. Sin. | pmid:25891088 |
| Moscovici BK et al. | Treatment of Sjögren's syndrome dry eye using 0.03% tacrolimus eye drop: Prospective double-blind randomized study. | 2015 | Cont Lens Anterior Eye | pmid:25956572 |
| Kim D et al. | Hydrogen sulfide and hypoxia-induced changes in TASK (K2P3/9) activity and intracellular Ca(2+) concentration in rat carotid body glomus cells. | 2015 | Respir Physiol Neurobiol | pmid:25956223 |
| Papadopoulos-Köhn A et al. | Daily low-dose tacrolimus is a safe and effective immunosuppressive regimen during telaprevir-based triple therapy for hepatitis C virus recurrence after liver transplant. | 2015 | Transplantation | pmid:25208324 |
| Torres-EspÃn A et al. | Immunosuppression of allogenic mesenchymal stem cells transplantation after spinal cord injury improves graft survival and beneficial outcomes. | 2015 | J. Neurotrauma | pmid:25203134 |
| Bae JM et al. | Combination therapy with 308-nm excimer laser, topical tacrolimus, and short-term systemic corticosteroids for segmental vitiligo: A retrospective study of 159 patients. | 2015 | J. Am. Acad. Dermatol. | pmid:25956660 |
| Rojas L et al. | Effect of CYP3A5*3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies. | 2015 | Pharmacogenomics J. | pmid:25201288 |
| Ennaifer R et al. | Nodular hyperplasia of the gastrointestinal tract after liver transplantation: role of immunosuppressive therapy? A case report. | 2015 | Transplant. Proc. | pmid:25891739 |
| Chung YW et al. | Transcriptional activation of nuclear-related factor 2 by FK506 in Jurkat T cells. | 2015 | Transplant. Proc. | pmid:25891728 |
| Daunton A et al. | A cutaneous presentation of a common condition. | 2015 | BMJ | pmid:26681202 |
| Yang SS et al. | A single center, open-label, randomized pilot study to evaluate the safety and efficacy of tacrolimus modified release, Advagraf, versus tacrolimus twice daily, Prograf, in stable renal recipients (single). | 2015 | Transplant. Proc. | pmid:25891697 |
| Hur J et al. | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | 2015 | Chem. Res. Toxicol. | pmid:25811541 |
| Malvezzi P and Rostaing L | The safety of calcineurin inhibitors for kidney-transplant patients. | 2015 | Expert Opin Drug Saf | pmid:26329325 |
| Hempen CM et al. | Hematocrit-independent recovery of immunosuppressants from DBS using heated flow-through desorption. | 2015 | Bioanalysis | pmid:26327182 |
| Manuyakorn W et al. | In vitro cytokine changes after pediatric liver transplantation. | 2015 | Asian Pac. J. Allergy Immunol. | pmid:25840634 |
| Pidala J et al. | Prolonged sirolimus administration after allogeneic hematopoietic cell transplantation is associated with decreased risk for moderate-severe chronic graft-versus-host disease. | 2015 | Haematologica | pmid:25840599 |
| Tsai MK et al. | B cells and immunoglobulin in ABO-incompatible renal transplant patients receiving rituximab and double filtration plasmapheresis. | 2015 | J. Formos. Med. Assoc. | pmid:25839769 |
| Eaton KV et al. | Engineering macrophages to control the inflammatory response and angiogenesis. | 2015 | Exp. Cell Res. | pmid:26610863 |
| Rajaganapathy BR et al. | Intravesical Liposomal Tacrolimus Protects against Radiation Cystitis Induced by 3-Beam Targeted Bladder Radiation. | 2015 | J. Urol. | pmid:25839382 |
| Furlan SN et al. | Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention. | 2015 | Sci Transl Med | pmid:26606970 |
| Nagashima T and Minota S | Comment on: The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis. | 2015 | Rheumatology (Oxford) | pmid:25832615 |
| Vollmar J et al. | Efficacy and safety of a conversion from the original tacrolimus and mycophenolate mofetil to the generics Tacpan and Mowel after liver transplantation. | 2015 | Drug Des Devel Ther | pmid:26604701 |
| Burke MT et al. | Expression of Bcl-xL and Mcl-1 in the nonmelanoma skin cancers of renal transplant recipients. | 2015 | Am. J. Clin. Pathol. | pmid:25780003 |
| Nouchi A et al. | [Treatment of angiolymphoid hyperplasia with eosinophilia (ALHE) using topical tacrolimus: Two cases]. | 2015 | Ann Dermatol Venereol | pmid:25778634 |
| Diaz-Siso JR et al. | Initial experience of dual maintenance immunosuppression with steroid withdrawal in vascular composite tissue allotransplantation. | 2015 | Am. J. Transplant. | pmid:25777324 |
| Fujibayashi T et al. | Comparison of efficacy and safety of tacrolimus and methotrexate in combination with abatacept in patients with rheumatoid arthritis; a retrospective observational study in the TBC Registry. | 2015 | Mod Rheumatol | pmid:25775147 |
| Adotama P et al. | Patient satisfaction with different treatment modalities for vitiligo. | 2015 | J. Am. Acad. Dermatol. | pmid:25773415 |
| Lehman N et al. | Left subconjunctival hemorrhage · renal dysfunction · international normalized ratio of 4.5 · Dx? | 2015 | J Fam Pract | pmid:26551480 |
| Boloori A et al. | Characterization of Remitting and Relapsing Hyperglycemia in Post-Renal-Transplant Recipients. | 2015 | PLoS ONE | pmid:26551468 |
| Lightman S et al. | Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet's disease with upregulation of circulating regulatory T cells and reduction of Th17. | 2015 | Ann. Rheum. Dis. | pmid:25269831 |
| Mahajan R et al. | Co-localization of agminated congenital melanocytic nevi with vitiligo vulgaris: an unusual presentation. | 2015 | Int. J. Dermatol. | pmid:25039486 |
| TruneÄŒka P et al. | Renal Function in De Novo Liver Transplant Recipients Receiving Different Prolonged-Release Tacrolimus Regimens-The DIAMOND Study. | 2015 | Am. J. Transplant. | pmid:25707487 |
| Adam R et al. | Improved survival in liver transplant recipients receiving prolonged-release tacrolimus in the European Liver Transplant Registry. | 2015 | Am. J. Transplant. | pmid:25703527 |
| Yokoyama Y et al. | Corticosteroid-sparing effect of tacrolimus in the initial treatment of dermatomyositis and polymyositis. | 2015 | Mod Rheumatol | pmid:25775144 |
| Asrani SK and O'Leary JG | Can one pill a day keep rejection away? | 2015 | Am. J. Transplant. | pmid:25703394 |
| Guethoff S et al. | De novo sirolimus with low-dose tacrolimus versus full-dose tacrolimus with mycophenolate mofetil after heart transplantation--8-year results. | 2015 | J. Heart Lung Transplant. | pmid:25701373 |
| Chen QQ et al. | Kaposi's Varicelliform Eruption During Long-term Treatment of Rosacea with 0.03% Tacrolimus Ointment. | 2015 | Chin. Med. J. | pmid:26481759 |
| Kim M et al. | Nail lichen striatus: report of seven cases and review of the literature. | 2015 | Int. J. Dermatol. | pmid:26474189 |
| Badri P et al. | Pharmacokinetics and dose recommendations for cyclosporine and tacrolimus when coadministered with ABT-450, ombitasvir, and dasabuvir. | 2015 | Am. J. Transplant. | pmid:25708713 |
| Peksa GD et al. | Dosing algorithm for concomitant administration of sirolimus, tacrolimus, and an azole after allogeneic hematopoietic stem cell transplantation. | 2015 | J Oncol Pharm Pract | pmid:24938293 |
| Cen J et al. | The new immunosuppressant, isogarcinol, binds directly to its target enzyme calcineurin, unlike cyclosporin A and tacrolimus. | 2015 | Biochimie | pmid:25701551 |
| Park JH et al. | Comparative study of tacrolimus and bevacizumab on corneal neovascularization in rabbits. | 2015 | Cornea | pmid:25651492 |
| Shengyou Y et al. | Influence of tacrolimus on podocyte injury inducted by angiotensin II. | 2015 | J Renin Angiotensin Aldosterone Syst | pmid:25650384 |
| Carenco C et al. | Tacrolimus and the risk of solid cancers after liver transplant: a dose effect relationship. | 2015 | Am. J. Transplant. | pmid:25648361 |
| Mizokami D et al. | Tacrolimus prevents laryngotracheal stenosis in an acute-injury rat model. | 2015 | Laryngoscope | pmid:25647147 |
| Ferjani H et al. | Tacrolimus and mycophenolate mofetil associations: Induction of oxidative stress or antioxidant effect? | 2015 | Hum Exp Toxicol | pmid:25645822 |
| Coelho R et al. | Nodular Regenerative Hyperplasia after Liver Transplantation Complicated with Inferior Vena Cava Stenosis: a Clue for Etiopathogenesis? | 2015 | J Gastrointestin Liver Dis | pmid:26405712 |
| Romanowski M et al. | Interleukin-17 gene polymorphisms in patients with post-transplant diabetes mellitus. | 2015 | Eur Rev Med Pharmacol Sci | pmid:26400516 |
| RodrÃguez-Perálvarez M et al. | Everolimus is safe within the first month after liver transplantation. | 2015 | Transpl. Immunol. | pmid:26392195 |
| Sahin G et al. | Association between endothelial and platelet function markers and adiponectin in renal transplanted recipients on cyclosporine and tacrolimus immunosuppression based therapy. | 2015 | Nephrology (Carlton) | pmid:25650527 |
| Sato M et al. | Multifocal Fibrosclerosis with Hypertrophic Pachymeningitis and a Soft Tissue Mass around the Thoracic Vertebral Bodies: A Case Report with Review of the Literature. | 2015 | Intern. Med. | pmid:26328659 |
| Pérez-López I et al. | Koebner phenomenon in a patient with lichen sclerosus following a jellyfish sting: an exceptional morphology. | 2015 | Actas Dermosifiliogr | pmid:25597413 |
| Niioka T et al. | Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation. | 2015 | Int J Mol Sci | pmid:25594874 |
| Chittock J et al. | Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. | 2015 | Acta Derm. Venereol. | pmid:25594610 |
| Ling Q et al. | Donor PPARα Gene Polymorphisms Influence the Susceptibility to Glucose and Lipid Disorders in Liver Transplant Recipients: A Strobe-Compliant Observational Study. | 2015 | Medicine (Baltimore) | pmid:26334901 |
| Knops N et al. | The functional implications of common genetic variation in CYP3A5 and ABCB1 in human proximal tubule cells. | 2015 | Mol. Pharm. | pmid:25590378 |
| Koch M et al. | De novo mTOR inhibitor-based immunosuppression in ABO-incompatible kidney transplantation. | 2015 | Clin Transplant | pmid:26333844 |
| Ge Y et al. | The efficacy of tacrolimus in patients with refractory dermatomyositis/polymyositis: a systematic review. | 2015 | Clin. Rheumatol. | pmid:26328518 |
| Graham F et al. | Tacrolimus use in renal and cardiac pediatric transplantation: no increased risk of food allergies. | 2015 | Ann. Allergy Asthma Immunol. | pmid:26094803 |
| Velioglu A et al. | Association of BK Virus Titers With Lymphocyte Count in Renal Transplant Patients. | 2015 | Transplant. Proc. | pmid:26093733 |
| Demir T et al. | Cancer Screening of Renal Transplant Patients Undergoing Long-Term Immunosuppressive Therapy. | 2015 | Transplant. Proc. | pmid:26093731 |
| Park J et al. | Iron overload triggers mitochondrial fragmentation via calcineurin-sensitive signals in HT-22 hippocampal neuron cells. | 2015 | Toxicology | pmid:26318285 |
| Shi RZ et al. | Rapid measurement of tacrolimus in whole blood by paper spray-tandem mass spectrometry (PS-MS/MS). | 2015 | Clin. Chim. Acta | pmid:25540885 |
| Yang F et al. | A clinicopathological study of renal biopsies from 288 elderly patients: analysis based on 4,185 cases. | 2015 | Int Urol Nephrol | pmid:25539617 |
| Webb NJ et al. | Corticosteroid-free Kidney Transplantation Improves Growth: 2-Year Follow-up of the TWIST Randomized Controlled Trial. | 2015 | Transplantation | pmid:25539467 |
| Schaap MM et al. | A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens. | 2015 | Arch. Toxicol. | pmid:25270620 |
| Yoo MC et al. | Steroid-free Liver Transplantation Using Rabbit Antithymocyte Globulin Induction in 500 Consecutive Patients. | 2015 | Transplantation | pmid:25539464 |
| Boluda ER | Pediatric small bowel transplantation. | 2015 | Curr Opin Organ Transplant | pmid:26262456 |
| Offer K et al. | Efficacy of tacrolimus/mycophenolate mofetil as acute graft-versus-host disease prophylaxis and the impact of subtherapeutic tacrolimus levels in children after matched sibling donor allogeneic hematopoietic cell transplantation. | 2015 | Biol. Blood Marrow Transplant. | pmid:25536217 |
| Seeling W et al. | Knowledge-based immunosuppressive therapy for kidney transplant patients--from theoretical model to clinical integration. | 2015 | Stud Health Technol Inform | pmid:26262418 |
| Wardhana EA and Datau | A patient with plaque type morphea mimicking systemic lupus erythematosus. | 2015 | Acta Med Indones | pmid:26260557 |
| Kim SH et al. | Conversion of twice-daily to once-daily tacrolimus is safe in stable adult living donor liver transplant recipients. | 2015 | HBPD INT | pmid:26256081 |
| Clift DE et al. | Effects of embryonic cyclosporine exposures on brain development and behavior. | 2015 | Behav. Brain Res. | pmid:25591474 |
| Duvoux C et al. | Sustained virological response to antiviral therapy in a randomized trial of cyclosporine versus tacrolimus in liver transplant patients with recurrent hepatitis C infection. | 2015 | Ann. Transplant. | pmid:25588713 |
| van Boekel GA et al. | Delayed trough level measurement with the use of prolonged-release tacrolimus. | 2015 | Transpl. Int. | pmid:25474192 |
| Gallagher HM et al. | Erratic tacrolimus exposure, assessed using the standard deviation of trough blood levels, predicts chronic lung allograft dysfunction and survival. | 2015 | J. Heart Lung Transplant. | pmid:26186804 |
| Li Y et al. | Differential regulation of Tregs and Th17/Th1 cells by a sirolimus-based regimen might be dependent on STAT-signaling in renal transplant recipients. | 2015 | Int. Immunopharmacol. | pmid:26186486 |
| Togashi M et al. | Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease. | 2015 | Eur. J. Clin. Pharmacol. | pmid:26184414 |
| Toole B et al. | Evaluation of the New Cyclosporine and Tacrolimus Automated Electrochemiluminescence Immunoassays under Field Conditions. | 2015 | Clin. Lab. | pmid:26554251 |
| Shen T et al. | Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. | 2015 | World J. Gastroenterol. | pmid:26034381 |
| Spiekerkoetter E et al. | Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:26177174 |
| Inamoto Y et al. | Tacrolimus versus Cyclosporine after Hematopoietic Cell Transplantation for Acquired Aplastic Anemia. | 2015 | Biol. Blood Marrow Transplant. | pmid:26033280 |
| Regelmann MO et al. | New-onset diabetes mellitus after pediatric liver transplantation. | 2015 | Pediatr Transplant | pmid:26032592 |