tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mercuri A et al. | In vitro and in silico characterisation of Tacrolimus released under biorelevant conditions. | 2016 | Int J Pharm | pmid:27737809 |
| Ochi H et al. | Notalgia paresthetica: treatment with topical tacrolimus. | 2016 | J Eur Acad Dermatol Venereol | pmid:25388817 |
| Jain A et al. | Tacrolimus and curcumin co-loaded liposphere gel: Synergistic combination towards management of psoriasis. | 2016 | J Control Release | pmid:27725194 |
| Muduma G et al. | Systematic Review and Meta-Analysis of Tacrolimus versus Ciclosporin as Primary Immunosuppression After Liver Transplant. | 2016 | PLoS ONE | pmid:27812112 |
| Deng S et al. | Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1. | 2016 | Mol Med Rep | pmid:27633115 |
| Størset E et al. | Low-target tacrolimus in de novo standard risk renal transplant recipients: A single-centre experience. | 2016 | Nephrology (Carlton) | pmid:26854648 |
| Chen YF et al. | Tacrolimus inhibits vasoconstriction by increasing Ca(2+) sparks in rat aorta. | 2016 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26838733 |
| Pathak S et al. | Preparation of High-Payload, Prolonged-Release Biodegradable Poly(lactic-co-glycolic acid)-Based Tacrolimus Microspheres Using the Single-Jet Electrospray Method. | 2016 | Chem. Pharm. Bull. | pmid:26833445 |
| Novosel MK and Bistrup C | Discontinuation of steroids in ABO-incompatible renal transplantation. | 2016 | Transpl. Int. | pmid:26706618 |
| Witt LJ et al. | Benefit of adjunctive tacrolimus in connective tissue disease-interstitial lung disease. | 2016 | Pulm Pharmacol Ther | pmid:26762710 |
| Dayal S et al. | Treatment of Childhood Vitiligo Using Tacrolimus Ointment with Narrowband Ultraviolet B Phototherapy. | 2016 | Pediatr Dermatol | pmid:27699846 |
| Bakardzhiev I et al. | Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem. | 2016 | Wien Med Wochenschr | pmid:26762262 |
| Jones-Hughes T et al. | Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model. | 2016 | Health Technol Assess | pmid:27578428 |
| Kravljaca M et al. | The importance of MDR1 gene polymorphisms for tacrolimus dosage. | 2016 | Eur J Pharm Sci | pmid:26705892 |
| Åžavk E | Neurologic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578080 |
| Georgiou GK et al. | Calcineurin inhibitors and male fertility after renal transplantation - a review. | 2016 | Andrologia | pmid:26341518 |
| Herden U et al. | Early Initiation of Everolimus After Liver Transplantation: A Single-Center Experience. | 2016 | Ann. Transplant. | pmid:26842532 |
| Yamaguchi Y et al. | Plasma cell cheilitis successfully treated with topical calcineurin inhibitors. | 2016 | Eur J Dermatol | pmid:27502182 |
| Early CR et al. | Effect of metronidazole use on tacrolimus concentrations in transplant patients treated for Clostridium difficile. | 2016 | Transpl Infect Dis | pmid:27501504 |
| Turrión-Merino L et al. | A Case Series of 4 Patients With Peristomal Pyoderma Gangrenosum: Review of Risk Factors and Treatment Response. | 2016 | Actas Dermosifiliogr | pmid:26626501 |
| Uemoto S et al. | Advantage of tacrolimus/mycophenolate mofetil regimen for cytotoxic T cell-mediated defence and its inhibition by additive steroid administration in high-risk liver transplant recipients. | 2016 | Clin. Exp. Immunol. | pmid:26560892 |
| Shijo T et al. | A mismatch between MRI lesions and SPECT hypoperfusion in tacrolimus-related encephalopathy. | 2016 | J. Neurol. Sci. | pmid:27423609 |
| Chen Y et al. | Clinicopathological features and prognosis of Kimura's disease with renal involvement in Chinese patients. | 2016 | Clin. Nephrol. | pmid:27142199 |
| Hermans C et al. | Atypical discrete papular lichen myxedematosus associated with monoclonal gammopathy: report of four cases and review of the literature. | 2016 | J Eur Acad Dermatol Venereol | pmid:27422288 |
| Zhang Y et al. | Effect of FK506 on apoptosis of facial motor neurons in rats and its possible mechanism. | 2016 | Eur Arch Otorhinolaryngol | pmid:25784181 |
| MacDonald C et al. | Acute kidney injury after heart transplant in young children: risk factors and outcomes. | 2016 | Pediatr. Nephrol. | pmid:26559064 |
| Vanhove T et al. | Comparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance. | 2016 | Br J Clin Pharmacol | pmid:27501475 |
| Stiehl SR et al. | Tacrolimus interaction with dexmedetomidine--a case report. | 2016 | Pediatr Transplant | pmid:26493547 |
| Kim JD et al. | Single-Center Experience of ABO-Incompatible Living-Donor Liver Transplantation With a New Simplified Intravenous Immunoglobulin Protocol: A Propensity Score-Matching Analysis. | 2016 | Transplant. Proc. | pmid:27320573 |
| Kato H et al. | Long-Term Influence of CYP3A5 Gene Polymorphism on Pharmacokinetics of Tacrolimus and Patient Outcome After Living Donor Liver Transplantation. | 2016 | Transplant. Proc. | pmid:27320564 |
| Federico S et al. | Sublingual administration improves systemic exposure of tacrolimus in kidney transplant recipients: comparison with oral administration. | 2016 | Eur. J. Clin. Invest. | pmid:27240092 |
| Kang SW et al. | Inhibition of senescence and promotion of the proliferation of chondrocytes from articular cartilage by CsA and FK506 involves inhibition of p38MAPK. | 2016 | Mech. Ageing Dev. | pmid:26704447 |
| Prytuła A et al. | Factors associated with 1,25-dihydroxyvitamin D3 concentrations in liver transplant recipients: a prospective observational longitudinal study. | 2016 | Endocrine | pmid:26433738 |
| Lazelle RA et al. | Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension. | 2016 | J. Am. Soc. Nephrol. | pmid:26432904 |
| Prytuła AA et al. | The Effect of Weight and CYP3A5 Genotype on the Population Pharmacokinetics of Tacrolimus in Stable Paediatric Renal Transplant Recipients. | 2016 | Clin Pharmacokinet | pmid:27138785 |
| Romano C et al. | Management of Acute Severe Colitis in Children With Ulcerative Colitis in the Biologics Era. | 2016 | Pediatrics | pmid:27244779 |
| Kim MJ et al. | Effect of Immunosuppressive Drugs on the Changes of Serum Galactose-Deficient IgA1 in Patients with IgA Nephropathy. | 2016 | PLoS ONE | pmid:27930655 |
| Shin J et al. | Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. | 2016 | Skelet Muscle | pmid:26949511 |
| Bianic F et al. | Cost-effectiveness of everolimus plus reduced tacrolimus in de novo liver-recipients in the Italian setting. | 2016 | J Med Econ | pmid:27081739 |
| Gambarino S et al. | Human Cytomegalovirus Impact on mir-146a Expression Levels in Kidney Transplant Patients. | 2016 | Viral Immunol. | pmid:27077822 |
| Saeki H et al. | Clinical Practice Guidelines for the Management of Atopic Dermatitis 2016. | 2016 | J. Dermatol. | pmid:27076388 |
| Mettang T | Uremic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578082 |
| Mok CC et al. | Tacrolimus versus mycophenolate mofetil for induction therapy of lupus nephritis: a randomised controlled trial and long-term follow-up. | 2016 | Ann. Rheum. Dis. | pmid:25550339 |
| Suarez Benjumea A et al. | Hepatitis C Virus in Kidney Transplant Recipients: A Problem on the Path to Eradication. | 2016 | Transplant. Proc. | pmid:27932111 |
| Xie L et al. | Pretransplantation Risk Factors Associated With New-onset Diabetes After Living-donor Kidney Transplantation. | 2016 | Transplant. Proc. | pmid:27931572 |
| Rodriguez Cubillo B et al. | Risk Factors of Recurrence of Diabetic Nephropathy in Renal Transplants. | 2016 | Transplant. Proc. | pmid:27932117 |
| Pallet N et al. | Long-Term Clinical Impact of Adaptation of Initial Tacrolimus Dosing to CYP3A5 Genotype. | 2016 | Am. J. Transplant. | pmid:26990694 |
| Awdishu L and Joy MS | Role of Pharmacogenomics in Kidney Disease and Injury. | 2016 | Adv Chronic Kidney Dis | pmid:26979149 |
| Song GW et al. | A Pilot Study of the Pharmacokinetics of the Modified-Release Once-Daily Tacrolimus Formulation Administered to Living-Donor Liver Transplant Recipients. | 2016 | Exp Clin Transplant | pmid:26976646 |
| Stockwell J et al. | Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury. | 2016 | Neuropharmacology | pmid:26626486 |