tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Mouth Diseases D009059 5 associated lipids
Meningococcal Infections D008589 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Tang S and Lai KN Quiz page. Posttransplantation lymphoproliferative disorder (PTLD) involving the brain and the allograft. 2005 Am. J. Kidney Dis. pmid:15806458
Rao PS Nephrotic syndrome in patients with peripheral blood stem cell transplant. 2005 Am. J. Kidney Dis. pmid:15806483
de Mattos AM et al. Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future. 2000 Am. J. Kidney Dis. pmid:10676738
Kooman JP et al. A comparison between office and ambulatory blood pressure measurements in renal transplant patients with chronic transplant nephropathy. 2001 Am. J. Kidney Dis. pmid:11382685
Choudhry S et al. Efficacy and safety of tacrolimus versus cyclosporine in children with steroid-resistant nephrotic syndrome: a randomized controlled trial. 2009 Am. J. Kidney Dis. pmid:19268410
Haas M et al. Smooth muscle-specific actin levels in the urine of renal transplant recipients: correlation with cyclosporine or tacrolimus nephrotoxicity. 1999 Am. J. Kidney Dis. pmid:10401019
Wong TY et al. Parvovirus B19 infection causing red cell aplasia in renal transplantation on tacrolimus. 1999 Am. J. Kidney Dis. pmid:10585325
Pescovitz MD and Govani M Sirolimus and mycophenolate mofetil for calcineurin-free immunosuppression in renal transplant recipients. 2001 Am. J. Kidney Dis. pmid:11583940
Tang S et al. Use of tacrolimus in steroid- and cyclophosphamide-resistant minimal change nephrotic syndrome. 2003 Am. J. Kidney Dis. pmid:14582073
Pham PT et al. Cyclosporine and tacrolimus-associated thrombotic microangiopathy. 2000 Am. J. Kidney Dis. pmid:11007689
Revelo MP et al. A 14-year-old boy with kidney allograft failure in the first month after transplantation. 2000 Am. J. Kidney Dis. pmid:11007695
Wong KM et al. Abbreviated tacrolimus area-under-the-curve monitoring for renal transplant recipients. 2000 Am. J. Kidney Dis. pmid:10739787
Böhmig GA et al. Role of humoral immune reactions as target for antirejection therapy in recipients of a spousal-donor kidney graft. 2000 Am. J. Kidney Dis. pmid:10739788
Lum EL et al. Acute Kidney Allograft Rejection Precipitated by Lenalidomide Treatment for Multiple Myeloma. 2017 Am. J. Kidney Dis. pmid:28189378
Neylan JF et al. Assessment of the frequency and costs of posttransplantation hospitalizations in patients receiving tacrolimus versus cyclosporine. 1998 Am. J. Kidney Dis. pmid:9820446
First MR Renal transplantation for the nephrologist: new immunosuppressive drugs. 1992 Am. J. Kidney Dis. pmid:1371201
Paoletti E et al. ACE inhibitors and persistent left ventricular hypertrophy after renal transplantation: a randomized clinical trial. 2007 Am. J. Kidney Dis. pmid:17591533
Mertz D et al. Drug-drug interaction in a kidney transplant recipient receiving HIV salvage therapy and tacrolimus. 2009 Am. J. Kidney Dis. pmid:19346040
Israni A et al. Conversion to tacrolimus for the treatment of cyclosporine-associated nephrotoxicity in heart transplant recipients. 2002 Am. J. Kidney Dis. pmid:11877596
Grinyó JM et al. Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial. 2017 Am. J. Kidney Dis. pmid:27889299