tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Mouth Diseases D009059 5 associated lipids
Meningococcal Infections D008589 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Gupta AK and Versteeg SG Topical Treatment of Facial Seborrheic Dermatitis: A Systematic Review. 2017 Am J Clin Dermatol pmid:27804089
Yang LP and Curran MP Spotlight on topical pimecrolimus in pediatric atopic dermatitis. 2010 Am J Clin Dermatol pmid:20509720
Cheer SM and Plosker GL Tacrolimus ointment. A review of its therapeutic potential as a topical therapy in atopic dermatitis. 2001 Am J Clin Dermatol pmid:11770393
Ozden MG et al. Topical pimecrolimus 1% cream for resistant seborrheic dermatitis of the face: an open-label study. 2010 Am J Clin Dermatol pmid:20000875
Mertens JS et al. Morphea and Eosinophilic Fasciitis: An Update. 2017 Am J Clin Dermatol pmid:28303481
Frankel HC and Qureshi AA Comparative effectiveness of topical calcineurin inhibitors in adult patients with atopic dermatitis. 2012 Am J Clin Dermatol pmid:22263704
Kroft EB et al. Efficacy of topical tacrolimus 0.1% in active plaque morphea: randomized, double-blind, emollient-controlled pilot study. 2009 Am J Clin Dermatol pmid:19354332
Siegfried EC et al. Topical calcineurin inhibitors and lymphoma risk: evidence update with implications for daily practice. 2013 Am J Clin Dermatol pmid:23703374
Tjioe M et al. Topical macrolide immunomodulators: a role in the treatment of vitiligo? 2006 Am J Clin Dermatol pmid:16489839
Valdivielso-Ramos M et al. Significant improvement in extensive lichen sclerosus with tacrolimus ointment and PUVA. 2008 Am J Clin Dermatol pmid:18429647
Cook BA and Warshaw EM Role of topical calcineurin inhibitors in the treatment of seborrheic dermatitis: a review of pathophysiology, safety, and efficacy. 2009 Am J Clin Dermatol pmid:19222250
Lübbe J et al. Safety, efficacy, and dosage of 1% pimecrolimus cream for the treatment of atopic dermatitis in daily practice. 2006 Am J Clin Dermatol pmid:16605292
Ellis CN et al. Cost effectiveness of management of mild-to-moderate atopic dermatitis with 1% pimecrolimus cream in children and adolescents 2-17 years of age. 2006 Am J Clin Dermatol pmid:16605293
Wollina U The role of topical calcineurin inhibitors for skin diseases other than atopic dermatitis. 2007 Am J Clin Dermatol pmid:17492844
Ramirez R et al. Posterior Reversible Encephalopathy Syndrome After Orthotopic Heart Transplantation: A Case Report. 2017 Am J Case Rep pmid:28465499
Kawamura H et al. Rapid Induction Therapy with Oral Tacrolimus in Elderly Patients with Refractory Ulcerative Colitis Can Easily Lead to Elevated Tacrolimus Concentrations in Blood: A Report of 5 Cases. 2017 Am J Case Rep pmid:28411286
Udomkarnjananun S et al. An Unusual Manifestation of Calcineurin Inhibitor-Induced Pain Syndrome in Kidney Transplantation: A Case Report and Literature Review. 2018 Am J Case Rep pmid:29654227
Baran DA et al. Calcineurin inhibitor-associated early renal insufficiency in cardiac transplant recipients: risk factors and strategies for prevention and treatment. 2004 Am J Cardiovasc Drugs pmid:14967063
Russell JJ Topical tacrolimus: a new therapy for atopic dermatitis. 2002 Am Fam Physician pmid:12469964
Berke R et al. Atopic dermatitis: an overview. 2012 Am Fam Physician pmid:22962911