Machida M et al. |
Effect of temperature and hematocrit on plasma concentration of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721266
|
Kawauchi M et al. |
Plasma level of FK 506 in newborn goats and infant baboons. |
1991 |
Transplant. Proc. |
pmid:1721267
|
O'Neill EA et al. |
The FK 506-sensitive nature of the interleukin-2 promoter is derived from a specific array of multiple regulatory elements. |
1991 |
Transplant. Proc. |
pmid:1721298
|
Nelson PA et al. |
Effect of immunosuppressive drugs on cytokine gene transcription studied by message amplification phenotyping (MAPPing) polymerase chain reaction. |
1991 |
Transplant. Proc. |
pmid:1721299
|
Ishibashi M et al. |
Effect of FK 506 on generation of activated macrophages invading rejected skin allografts in rats: discrepancy of in vitro versus in vivo effects. |
1991 |
Transplant. Proc. |
pmid:1721330
|
Kawauchi M et al. |
Flow cytometric analysis of lymphocyte populations in FK 506-treated newborn goats. |
1991 |
Transplant. Proc. |
pmid:1721331
|
McCauley J et al. |
Renal transplantation under FK 506 in patients with previous loss of renal function due to hemolytic uremic syndrome. |
1991 |
Transplant. Proc. |
pmid:1721362
|
Zeevi A et al. |
Correlation between bioassayed plasma levels of FK 506 and lymphocyte growth from liver transplant biopsies with histological evidence of rejection. |
1991 |
Transplant. Proc. |
pmid:1703341
|
|
Japanese study of FK 506 on kidney transplantation: results of an early phase II study. Japanese FK 506 Study Group. |
1991 |
Transplant. Proc. |
pmid:1721363
|
van Hoek B et al. |
Recurrence of ductopenic rejection in liver allografts after retransplantation for vanishing bile duct syndrome. |
1991 |
Transplant. Proc. |
pmid:1703343
|
Scantlebury V et al. |
New onset of diabetes in FK 506 vs cyclosporine-treated kidney transplant recipients. |
1991 |
Transplant. Proc. |
pmid:1721395
|
Carroll PB et al. |
FK 506-associated diabetes mellitus in the pediatric transplant population is a rare complication. |
1991 |
Transplant. Proc. |
pmid:1721396
|
Langrehr JM et al. |
Indefinite small bowel allograft survival after limited immunosuppressive therapy is not due to specific hyporesponsiveness. |
1991 |
Transplant. Proc. |
pmid:1721425
|
Takeda Y et al. |
Effect of FK 506 on the survival of rat small bowel allografts. |
1991 |
Transplant. Proc. |
pmid:1721426
|
Brabletz T et al. |
The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer. |
1991 |
Nucleic Acids Res. |
pmid:1707162
|
Iwaki Y et al. |
Replacement of donor lymphoid tissue in small-bowel transplants. |
1991 |
Lancet |
pmid:1707470
|
Mochizuki M et al. |
A multicenter clinical open trial of FK 506 in refractory uveitis, including Behçet's disease. Japanese FK 506 Study Group on Refractory Uveitis. |
1991 |
Transplant. Proc. |
pmid:1721456
|
Roat MI et al. |
Treatment of Cogan's syndrome with FK 506: a case report. |
1991 |
Transplant. Proc. |
pmid:1721457
|
Carroll PB et al. |
The use of FK 506 in new-onset type I diabetes in man. |
1991 |
Transplant. Proc. |
pmid:1721458
|
Markus PM et al. |
FK 506 reverses acute graft-versus-host disease after allogeneic bone marrow transplantation in rats. |
1991 |
Surgery |
pmid:1713358
|
Farley DE et al. |
The effect of two new immunosuppressive agents, FK506 and didemnin B, in murine pregnancy. |
1991 |
Transplantation |
pmid:1713360
|
Thomson AW |
The immunosuppressive macrolides FK-506 and rapamycin. |
1991 |
Immunol. Lett. |
pmid:1717376
|
Takaya S et al. |
Positive crossmatch in primary human liver allografts under cyclosporine or FK 506 therapy. |
1991 |
Transplant. Proc. |
pmid:1703691
|
Steeves M et al. |
In-vitro interaction of a novel immunosuppressant, FK 506, and antacids. |
1991 |
J. Pharm. Pharmacol. |
pmid:1717676
|
Hildebrandt A et al. |
FK 506: short- and long-term treatment after cardiac transplantation in nonhuman primates. |
1991 |
Transplant. Proc. |
pmid:1703694
|
Altmeyer A et al. |
Unexpected up-regulation of gene expression by cyclosporin A and FK-506 in a T-cell lymphoma: both immunosuppressants augment Ly-6E antigen induction by interferon-gamma in the presence of ionomycin. |
1991 |
Int. J. Immunopharmacol. |
pmid:1726093
|
Gordon RD et al. |
Liver transplantation at the University of Pittsburgh, 1984 to 1990. |
1991 |
Clin Transpl |
pmid:1726458
|
Jordan ML et al. |
Initial studies with FK506 in renal transplantation. |
1991 Sep-Oct |
Cleve Clin J Med |
pmid:1718631
|
Kuo CJ et al. |
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. |
1992 |
Nature |
pmid:1614535
|
Andersson J et al. |
FK 506 and cyclosporine inhibit antigen- or mitogen-induced monokine and lymphokine production in vitro. |
1992 |
Transplant. Proc. |
pmid:1371621
|
Matsuura T et al. |
Blockade of interleukin-2 production from cloned T cells by cyclosporine and FK 506 assessed by proliferation assays in vitro. |
1992 |
Transplant. Proc. |
pmid:1371623
|
Moutabarrik A et al. |
In vitro FK506 kidney tubular cell toxicity. |
1992 |
Transpl. Int. |
pmid:14621743
|
Okamura N et al. |
Enhanced liver regeneration by FK 506 can be blocked by interleukin-1 alpha and interleukin-2. |
1992 |
Transplant. Proc. |
pmid:1371624
|
Moutabarrik A et al. |
FK506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells. |
1992 |
Transpl. Int. |
pmid:14621744
|
Sakr M et al. |
Effect of renal ischemia on plasma levels of FK 506 in rats. |
1992 |
Transplant. Proc. |
pmid:1371625
|
Stangl MJ et al. |
The use of FK506 and RS61443 for reversal of small-bowel rejection. |
1992 |
Transpl. Int. |
pmid:14621800
|
Kusne S et al. |
Infections during a randomized trial comparing cyclosporine to FK 506 immunosuppression in liver transplantation. |
1992 |
Transplant. Proc. |
pmid:1371626
|
Wijnen RM et al. |
Toxicology of FK506 in the cynomolgus monkey: a clinical, biochemical, and histopathological study. |
1992 |
Transpl. Int. |
pmid:14621844
|
Lee C et al. |
FK-506 binding protein from Tolypocladium inflatum: resistance of FKBP/FK-506 complex against proteolysis. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1371677
|
Edkins RD et al. |
Comparison of cyclosporine and FK506 effects on glutathione levels in rat cochlea, brain, liver and kidney. |
1992 |
Biochem. Pharmacol. |
pmid:1371687
|
Galat A et al. |
A rapamycin-selective 25-kDa immunophilin. |
1992 |
Biochemistry |
pmid:1371698
|
Hanawa H et al. |
An immunosuppressant compound, FK-506, prevents the progression of autoimmune myocarditis in rats. |
1992 |
Clin. Immunol. Immunopathol. |
pmid:1371730
|
Hiraoka Y et al. |
The effects of FK-506, a novel and potent immunosuppressant, upon murine Coxsackievirus B3 myocarditis. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1372051
|
Höllsberg P et al. |
Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. |
1992 |
J. Immunol. |
pmid:1374452
|
Schreiber SL and Crabtree GR |
The mechanism of action of cyclosporin A and FK506. |
1992 |
Immunol. Today |
pmid:1374612
|
Demetris AJ et al. |
Conversion of liver allograft recipients from cyclosporine to FK506 immunosuppressive therapy--a clinicopathologic study of 96 patients. |
1992 |
Transplantation |
pmid:1374944
|
Bundick RV et al. |
FK506 as an agonist to induce inhibition of interleukin 2 production. |
1992 |
Transplantation |
pmid:1374947
|
Sakr M et al. |
The protective effect of FK506 pretreatment against renal ischemia/reperfusion injury in rats. |
1992 |
Transplantation |
pmid:1374948
|
Lepre CA et al. |
Solution structure of FK506 bound to FKBP-12. |
1992 |
FEBS Lett. |
pmid:1375171
|
Ruff VA et al. |
FKBP-12 is not an inhibitor of protein kinase C. |
1992 |
Immunol. Invest. |
pmid:1375189
|
Kawaguchi S |
[Effects of FK506 on aminonucleoside-induced nephrotic rats]. |
1992 |
Nihon Jinzo Gakkai Shi |
pmid:1375300
|
Sigal NH and Dumont FJ |
Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction. |
1992 |
Annu. Rev. Immunol. |
pmid:1375473
|
Jain A et al. |
Intravenous, oral pharmacokinetics, and oral dosing of FK 506 in small bowel transplant patients. |
1992 |
Transplant. Proc. |
pmid:1376518
|
Masutani H et al. |
Suppression of the histologic changes of GVHD by FK 506 in rat small bowel transplantation. |
1992 |
Transplant. Proc. |
pmid:1376519
|
Santiago SF et al. |
Effect of short-term immunosuppressive therapy with FK 506 or CyA on the donor in small intestine allotransplantation in rats. |
1992 |
Transplant. Proc. |
pmid:1376520
|
Utsunomiya H et al. |
Effect of FK 506 on orthotopic small bowel transplantation in rats. |
1992 |
Transplant. Proc. |
pmid:1376521
|
Yagihashi A et al. |
Changes in cell surface markers in human small bowel transplantation with FK 506. |
1992 |
Transplant. Proc. |
pmid:1376522
|
Abu-Elmagd K et al. |
Management of intestinal transplantation in humans. |
1992 |
Transplant. Proc. |
pmid:1376523
|
Takaori K et al. |
Basic study on immunologic effects of cyclosporine and FK 506 for application to pancreatic transplantation. |
1992 |
Transplant. Proc. |
pmid:1376531
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation using the cuff technique in rats. |
1992 |
Transplant. Proc. |
pmid:1376532
|
Demetris AJ et al. |
Donor dendritic cells after liver and heart allotransplantation under short-term immunosuppression. |
1992 |
Lancet |
pmid:1376851
|
Ichihashi T et al. |
Haemolytic uraemic syndrome during FK506 therapy. |
1992 |
Lancet |
pmid:1376852
|
Lemster B et al. |
Cytokine gene expression in murine lymphocytes activated in the presence of FK 506, bredinin, mycophenolic acid, or brequinar sodium. |
1992 |
Transplant. Proc. |
pmid:1281576
|
Tze WJ et al. |
FK 506: an effective immunosuppressant for islet xenotransplantation. |
1992 |
Transplant. Proc. |
pmid:1281577
|
Kamei T et al. |
Established intraportal islet allograft is rejected despite the acceptance of donor-specific second cardiac allograft. |
1992 |
Transplant. Proc. |
pmid:1281579
|
Woo J et al. |
FK 506 treatment following syngeneic bone marrow transplantation does not inhibit clonal deletion of V beta 5+ or V beta 11+ T cells. |
1992 |
Transplant. Proc. |
pmid:1281583
|
Souza ER et al. |
Acute effects of FK 506 on glomerular hemodynamics. |
1992 |
Transplant. Proc. |
pmid:1281585
|
Hanke JH et al. |
FK506 and rapamycin selectively enhance degradation of IL-2 and GM-CSF mRNA. |
1992 |
Lymphokine Cytokine Res. |
pmid:1281674
|
Logan TM et al. |
Side chain and backbone assignments in isotopically labeled proteins from two heteronuclear triple resonance experiments. |
1992 |
FEBS Lett. |
pmid:1281793
|
Bergstrand H et al. |
Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1281879
|
DiLella AG et al. |
Chromosomal band assignments of the genes encoding human FKBP12 and FKBP13. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1281998
|
Sawada M et al. |
Down regulation of CD4 expression in cultured microglia by immunosuppressants and lipopolysaccharide. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1282000
|
Rondeau E |
[Mechanism of action of the new immunosuppressants: cyclosporin A, FK 506 and rapamycin]. |
1992 |
Nephrologie |
pmid:1379348
|
Schreiber SL |
Immunophilin-sensitive protein phosphatase action in cell signaling pathways. |
1992 |
Cell |
pmid:1379518
|
Aldape RA et al. |
Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506-calcineurin complex. |
1992 |
J. Biol. Chem. |
pmid:1379588
|
Langrehr JM et al. |
Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat. |
1992 |
J. Clin. Invest. |
pmid:1379617
|
Kumano K et al. |
[Functional and morphological changes in rat kidney induced by FK506 and its reversal by various vasodilators]. |
1992 |
Nippon Hinyokika Gakkai Zasshi |
pmid:1379657
|
Woodle ES et al. |
FK506: inhibition of humoral mechanisms of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1379749
|
Sato K et al. |
Effectiveness of triple drug immunosuppression for pancreaticoduodenal allotransplantation in dogs. |
1992 |
Transplant. Proc. |
pmid:1379753
|
Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs receiving FK 506. |
1992 |
Transplant. Proc. |
pmid:1379754
|
Yoshimura R et al. |
A comparative study of cyclosporine vs FK 506: role of kidney microsomal cytochrome P-450. |
1992 |
Transplant. Proc. |
pmid:1379755
|
Yamada K et al. |
FK 506-induced juxtaglomerular apparatus hyperplasia and tubular damage in rat kidney--morphologic and biologic analysis. |
1992 |
Transplant. Proc. |
pmid:1379756
|
Petros AM et al. |
Conformation of two non-immunosuppressive FK506 analogs when bound to FKBP by isotope-filtered NMR. |
1992 |
FEBS Lett. |
pmid:1380470
|
Van Thiel DH et al. |
FK 506 reduces the injury experienced following renal ischemia and reperfusion. |
1992 |
Ren Fail |
pmid:1380720
|
Bolton C |
The efficacy of cyclosporin A, FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE). |
1992 |
Agents Actions |
pmid:1380765
|
Terada N et al. |
Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1380801
|
Friccius H et al. |
The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells. |
1992 |
Int. J. Immunopharmacol. |
pmid:1380951
|
Dumont FJ et al. |
The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin. |
1992 |
J. Exp. Med. |
pmid:1380976
|
Norris AA et al. |
Protective effects of cyclophosphamide, cyclosporin A and FK506 against antigen-induced lung eosinophilia in guinea-pigs. |
1992 |
Clin. Exp. Immunol. |
pmid:1381297
|
Karpas A et al. |
Inhibition of human immunodeficiency virus and growth of infected T cells by the immunosuppressive drugs cyclosporin A and FK 506. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1381509
|
Yatscoff RW and Shaw LM |
Therapeutic monitoring of cyclosporine, FK-506, and rapamycin. |
1992 |
Ther Drug Monit |
pmid:1381530
|
Griffin AD et al. |
FK 506 in canine renal transplantation. |
1992 |
Transplant. Proc. |
pmid:1384209
|
Griffiths RJ et al. |
Characterisation of passively transferred antigen arthritis induced by methylated bovine serum albumin in the rat: effect of FK 506 on arthritis development. |
1992 |
Agents Actions |
pmid:1384284
|
Todo S et al. |
Intestinal transplantation in composite visceral grafts or alone. |
1992 |
Ann. Surg. |
pmid:1384443
|
Massol N et al. |
Rabbit FKBP59-heat shock protein binding immunophillin (HBI) is a calmodulin binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1384470
|
Siekierka JJ and Sigal NH |
FK-506 and cyclosporin A: immunosuppressive mechanism of action and beyond. |
1992 |
Curr. Opin. Immunol. |
pmid:1384551
|
Hultsch T et al. |
The effect of the immunophilin ligands rapamycin and FK506 on proliferation of mast cells and other hematopoietic cell lines. |
1992 |
Mol. Biol. Cell |
pmid:1384815
|
Petros AM et al. |
Identification of solvent-exposed regions of an FK-506 analog, ascomycin, bound to FKBP using a paramagnetic probe. |
1992 |
J. Biomol. NMR |
pmid:1384850
|
Liu J et al. |
The effects of FK-506 and cyclosporin A on the proliferation of PHA-stimulated T cells in response to IL-2, IL-4 or IL-6. |
1992 |
Int. Arch. Allergy Immunol. |
pmid:1384862
|
Mochizuki M et al. |
Preclinical and clinical study of FK506 in uveitis. |
1992 |
Curr. Eye Res. |
pmid:1385045
|