tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Digestive System Fistula D016154 1 associated lipids
Feline Acquired Immunodeficiency Syndrome D016181 1 associated lipids
AIDS-Associated Nephropathy D016263 1 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Lymphoma, T-Cell, Cutaneous D016410 4 associated lipids
Granuloma Annulare D016460 1 associated lipids
Sweet Syndrome D016463 1 associated lipids
Fungemia D016469 2 associated lipids
Pemphigus, Benign Familial D016506 3 associated lipids
Foot Ulcer D016523 4 associated lipids
Neoplasms, Second Primary D016609 4 associated lipids
Critical Illness D016638 13 associated lipids
Still's Disease, Adult-Onset D016706 2 associated lipids
Feline Infectious Peritonitis D016766 1 associated lipids
Polyendocrinopathies, Autoimmune D016884 1 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Arthritis, Reactive D016918 3 associated lipids
Meningitis, Cryptococcal D016919 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Yang J et al. Zinc finger protein A20 protects rats against chronic liver allograft dysfunction. 2012 World J. Gastroenterol. pmid:22826618
Zhou J et al. Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: Report of an initial experience. 2006 World J. Gastroenterol. pmid:16718799
Song JL et al. Minimizing tacrolimus decreases the risk of new-onset diabetes mellitus after liver transplantation. 2016 World J. Gastroenterol. pmid:26877618
Li DW et al. Risk factors for new onset diabetes mellitus after liver transplantation: A meta-analysis. 2015 World J. Gastroenterol. pmid:26034369
Filipec Kanizaj T and Mijic M Inflammatory bowel disease in liver transplanted patients. 2017 World J. Gastroenterol. pmid:28566881
Guo YW et al. Successful treatment of ileal ulcers caused by immunosuppressants in two organ transplant recipients. 2016 World J. Gastroenterol. pmid:27350740
Kang YZ et al. Autoimmune hepatitis-primary biliary cirrhosis concurrent with biliary stricture after liver transplantation. 2015 World J. Gastroenterol. pmid:25717264
Schott E et al. Development of ulcerative colitis in a patient with multiple sclerosis following treatment with interferon beta 1a. 2007 World J. Gastroenterol. pmid:17659718
Schumacher G et al. Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth. 2005 World J. Gastroenterol. pmid:15770715
Jia JJ et al. ''Minimizing tacrolimus'' strategy and long-term survival after liver transplantation. 2014 World J. Gastroenterol. pmid:25170223
Hao JC et al. Effect of low-dose tacrolimus with mycophenolate mofetil on renal function following liver transplantation. 2014 World J. Gastroenterol. pmid:25170222
Eshraghian A et al. Post-transplant lymphoproliferative disorder after liver transplantation: Incidence, long-term survival and impact of serum tacrolimus level. 2017 World J. Gastroenterol. pmid:28275302
Wu SY et al. Comprehensive risk assessment for early neurologic complications after liver transplantation. 2016 World J. Gastroenterol. pmid:27350733
Liu C et al. Cyclosporine A, FK-506, 40-0-[2-hydroxyethyl]rapamycin and mycophenolate mofetil inhibit proliferation of human intrahepatic biliary epithelial cells in vitro. 2005 World J. Gastroenterol. pmid:16437685
Kawakami K et al. Effects of oral tacrolimus as a rapid induction therapy in ulcerative colitis. 2015 World J. Gastroenterol. pmid:25684955
Lan X et al. Efficacy of immunosuppression monotherapy after liver transplantation: a meta-analysis. 2014 World J. Gastroenterol. pmid:25232269
Larsen FS et al. Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hepatitis. 2007 World J. Gastroenterol. pmid:17589903
Wietzke-Braun P et al. Initial steroid-free immunosuppression after liver transplantation in recipients with hepatitis C virus related cirrhosis. 2004 World J. Gastroenterol. pmid:15259068
Shao ZY et al. Prophylaxis of chronic kidney disease after liver transplantation--experience from west China. 2012 World J. Gastroenterol. pmid:22408361
Buchholz BM et al. Role of colectomy in preventing recurrent primary sclerosing cholangitis in liver transplant recipients. 2018 World J. Gastroenterol. pmid:30065563