tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hypertensive Encephalopathy D020343 1 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Cytomegalovirus Retinitis D017726 2 associated lipids
Rectal Fistula D012003 2 associated lipids
Vestibular Diseases D015837 2 associated lipids
Intestinal Atresia D007409 3 associated lipids
Priapism D011317 1 associated lipids
Kaposi Varicelliform Eruption D007617 1 associated lipids
Echinostomiasis D004451 1 associated lipids
Respiratory Tract Neoplasms D012142 2 associated lipids
Trichomonas Infections D014245 3 associated lipids
Deltaretrovirus Infections D006800 1 associated lipids
West Nile Fever D014901 1 associated lipids
Foot Ulcer D016523 4 associated lipids
Fibroadenoma D018226 2 associated lipids
Tinea Capitis D014006 1 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Facial Nerve Injuries D020220 1 associated lipids
Lymphocele D008210 1 associated lipids
End Stage Liver Disease D058625 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Saengram W et al. Extended release versus immediate release tacrolimus in kidney transplant recipients: a systematic review and meta-analysis. 2018 Eur. J. Clin. Pharmacol. pmid:29961086
Gadby F et al. [Pulmonary granuloma in an immunodepressed patient]. 2018 Rev Mal Respir pmid:29395568
Suetsugu K et al. Analysis of the variable factors influencing tacrolimus blood concentration during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation. 2017 Int. J. Hematol. pmid:27822915
Lim SW et al. Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress. 2017 Cell Death Dis pmid:28771227
Savaj S et al. Irreversible Lesions of Tacrolimus-induced Posterior Reversible Leukoencephalopathy Syndrome. 2017 Iran J Kidney Dis pmid:29190599
Liao JH et al. Gene Variations of Sixth Complement Component Affecting Tacrolimus Metabolism in Patients with Liver Transplantation for Hepatocellular Carcinoma. 2017 Chin. Med. J. pmid:28685716
An Q et al. High Colonization and Impaired Permeability Barrier in Facial Seborrheic Dermatitis. 2017 Chin. Med. J. pmid:28685715
Gao L et al. Synergistic Effects of Tacrolimus and Azoles against Exophiala dermatitidis. 2017 Antimicrob. Agents Chemother. pmid:28923863
Liang Q et al. The efficacy and safety of tacrolimus monotherapy in adult-onset nephrotic syndrome caused by idiopathic membranous nephropathy. 2017 Ren Fail pmid:28562168
Jin H et al. Inappropriate amounts of topical tacrolimus applied on Korean patients with eczema. 2017 J Dermatolog Treat pmid:27588441
Shen CL et al. Tacrolimus Blood Level Fluctuation Predisposes to Coexisting BK Virus Nephropathy and Acute Allograft Rejection. 2017 Sci Rep pmid:28512328
Aktürk S et al. Average Tacrolimus Trough Level in the First Month After Transplantation May Predict Acute Rejection. 2017 Transplant. Proc. pmid:28340806
Vanhove T et al. Effect of ABCB1 diplotype on tacrolimus disposition in renal recipients depends on CYP3A5 and CYP3A4 genotype. 2017 Pharmacogenomics J. pmid:27378609
Riva N et al. Therapeutic monitoring of pediatric transplant patients with conversion to generic tacrolimus. 2017 Farm Hosp pmid:28236795
Dai Y et al. A case report of coup de sabre patient with hair transplantation. 2017 J Dermatolog Treat pmid:28142293
Lewis K et al. Autoimmune enteropathy and hepatitis in pediatric heart transplant recipient. 2017 Pediatr Transplant pmid:28097735
Hayes W et al. Hypomagnesemia and increased risk of new-onset diabetes mellitus after transplantation in pediatric renal transplant recipients. 2017 Pediatr. Nephrol. pmid:28039534
Hu Y et al. FK506 suppresses hypoxia‑induced inflammation and protects tight junction function via the CaN‑NFATc1 signaling pathway in retinal microvascular epithelial cells. 2017 Mol Med Rep pmid:28901449
Andrews LM et al. Pharmacokinetic considerations related to therapeutic drug monitoring of tacrolimus in kidney transplant patients. 2017 Expert Opin Drug Metab Toxicol pmid:29084469
Vanhove T et al. Pretransplant 4β-hydroxycholesterol does not predict tacrolimus exposure or dose requirements during the first days after kidney transplantation. 2017 Br J Clin Pharmacol pmid:28603840