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The immunosuppressant FK506 prolongs transgene expression in brain following adenovirus-mediated gene transfer. |
1997 |
Neuroreport |
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Elimination of FK-506 by continuous hemodiafiltration in a liver transplant patient. |
1997 Jul-Aug |
ASAIO J. |
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1996 |
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Sinus arrest during tacrolimus (FK506) and digitalis treatment in a bone marrow transplant recipient. |
1997 |
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Mechanism of concordant corneal xenograft rejection in mice: synergistic effects of anti-leukocyte function-associated antigen-1 monoclonal antibody and FK506. |
1997 |
Transplantation |
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1997 |
Bone Marrow Transplant. |
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Recurrence of autoimmune hepatitis in children after liver transplantation. |
1997 |
J. Pediatr. Gastroenterol. Nutr. |
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Mean field analysis of FKBP12 complexes with FK506 and rapamycin: implications for a role of crystallographic water molecules in molecular recognition and specificity. |
1997 |
Proteins |
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Nerve xenograft transplantation. Immunosuppression with FK-506 and RS-61443. |
1997 |
J Hand Surg Br |
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Effect of the immunosupressant FK506 on excitation-contraction coupling and outward K+ currents in rat ventricular myocytes. |
1997 |
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[Experimental study of the effectiveness of immunosuppression therapy using FK506 and 15-deoxyspergualin in concordant xenotransplantation]. |
1997 |
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Cyclosporin A but not FK506 inhibits thyroid hormone-induced apoptosis in tadpole intestinal epithelium. |
1997 |
FASEB J. |
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The outcome of unrelated donor bone marrow transplantation in patients with hematologic malignancies using tacrolimus (FK506) and low dose methotrexate for graft-versus-host disease prophylaxis. |
1997 |
Biol. Blood Marrow Transplant. |
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Implication of CYP 3A in the toxicity of cyclosporin G (CsG), cyclosporin A (CsA) and FK506 on rat hepatocytes in primary culture. |
1997 |
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Tacrolimus and methotrexate for the prophylaxis of acute graft-versus-host disease in allogeneic bone marrow transplantation in patients with hematologic malignancies. |
1997 |
Bone Marrow Transplant. |
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Chemical and biological characterization of two FK506 analogs produced by targeted gene disruption in Streptomyces sp. MA6548. |
1997 |
J. Antibiot. |
pmid:9207912
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A cell growth switch. |
1997 |
Science |
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1997 |
J. Toxicol. Clin. Toxicol. |
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Self-reactive forbidden clones are confined to pathways of intermediate T-cell receptor cell differentiation even under immunosuppressive conditions. |
1997 |
Immunology |
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Age-related changes of sodium-dependent D-[3H]aspartate and [3H]FK506 binding in rat brain. |
1997 |
J Neural Transm |
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1997 |
Int. Rev. Immunol. |
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Int. Rev. Immunol. |
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Regulation of calcium-induced exocytosis from gastric chief cells by protein phosphatase-2B (calcineurin). |
1997 |
Biochim. Biophys. Acta |
pmid:9202177
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Measurement of tacrolimus (FK506) and its metabolites: a review of assay development and application in therapeutic drug monitoring and pharmacokinetic studies. |
1997 |
Ther Drug Monit |
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Immunosuppressor binding to the immunophilin FKBP59 affects the local structural dynamics of a surface beta-strand: time-resolved fluorescence study. |
1997 |
Biochemistry |
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Calcineurin: not just a simple protein phosphatase. |
1997 |
Biochem. Biophys. Res. Commun. |
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En bloc pancreas and kidney transplantation in a patient with limited vascular access. |
1997 |
Transplantation |
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Blood transfusions in liver recipients: a conundrum or a clear benefit in the cyclosporine/tacrolimus era? |
1997 |
Transplantation |
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Post-transplant lymphoproliferative disease in kidney transplant patients in the new immunosuppressive era. |
1997 |
Clin Transplant |
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Clinical features of acute reversible tacrolimus (FK 506) nephrotoxicity in kidney transplant recipients. |
1997 |
Clin Transplant |
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Effects of cyclosporin A and FK 506 on lipid metabolism and fibrinogen in kidney transplant recipients. |
1997 |
Clin Transplant |
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The use of tacrolimus and mycophenolate mofetil after cardiac transplantation. |
1997 |
Curr. Opin. Cardiol. |
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Pathophysiology and treatment of lipid perturbation after cardiac transplantation. |
1997 |
Curr. Opin. Cardiol. |
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J. Immunol. |
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Use of FK506 immunosuppressive therapy in pancreas transplantation. |
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J Transpl Coord |
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Review of immunosuppression for lung transplantation. Novel drugs, new uses for conventional immunosuppressants, and alternative strategies. |
1997 |
Clin. Chest Med. |
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Stimulatory roles of muscarinic acetylcholine receptors on T cell antigen receptor/CD3 complex-mediated interleukin-2 production in human peripheral blood lymphocytes. |
1997 |
Mol. Pharmacol. |
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1997 |
Surgery |
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Graft persistence effectively induces and maintains donor-specific unresponsiveness. |
1997 |
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Calcineurin is required for virulence of Cryptococcus neoformans. |
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Arthritis Rheum. |
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Dynamic equilibrium between calcineurin and kinase activities regulates the phosphorylation state and localization of the nuclear factor of activated T-cells. |
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Biochem. J. |
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Metabolism of tacrolimus (FK 506) in rat liver microsomes. Effect of rifampin and dexamethasone. |
1997 |
Res. Commun. Mol. Pathol. Pharmacol. |
pmid:9178371
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Cyclosporin A-sensitive calcium signaling represses NFkappaB activation in human bronchial epithelial cells and enhances NFkappaB activation in Jurkat T-cells. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9177287
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Kaposi's sarcoma in liver transplant recipients on FK506: two case reports. |
1997 |
Transplantation |
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[Dental and oral aspects in pediatric liver transplant patients. A comparison between the effects of cyclosporine A and FK 506]. |
1997 |
Minerva Stomatol |
pmid:9173223
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Rapid resolution of gingival hyperplasia after switching from cyclosporine A to tacrolimus. |
1997 |
J. Heart Lung Transplant. |
pmid:9171281
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Wang JH and Kelly PT |
Postsynaptic calcineurin activity downregulates synaptic transmission by weakening intracellular Ca2+ signaling mechanisms in hippocampal CA1 neurons. |
1997 |
J. Neurosci. |
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Transcriptional control in keratinocytes and fibroblasts using synthetic ligands. |
1997 |
J. Clin. Invest. |
pmid:9169490
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The pharmacokinetics of water-in-oil-in-water-type multiple emulsion of a new tacrolimus formulation. |
1997 |
Lipids |
pmid:9168461
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Time-dependent disposition of tacrolimus and its effect on endothelin-1 in liver allograft recipients. |
1997 May-Jun |
Pharmacotherapy |
pmid:9165550
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1997 |
J. Pediatr. Surg. |
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1997 |
Transpl. Int. |
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A local lymph node assay to analyse immunosuppressive effects of topically applied drugs. |
1997 |
Eur. J. Pharmacol. |
pmid:9163567
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Nifedipine interaction with tacrolimus in liver transplant recipients. |
1997 |
Ann Pharmacother |
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Lymphomatoid papulosis and FK 506. |
1997 |
Int. J. Dermatol. |
pmid:9159004
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van Hooff JP |
Pneumocystis carinii pneumonia after renal transplantation. |
1997 |
Transplantation |
pmid:9158038
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Striking augmentation of hematopoietic cell chimerism in noncytoablated allogeneic bone marrow recipients by FLT3 ligand and tacrolimus. |
1997 |
Transplantation |
pmid:9158008
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Delehanty LL et al. |
Apoptosis in a Fas-resistant, T-cell receptor-sensitive human leukaemic T-cell clone. |
1997 |
Immunology |
pmid:9155645
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Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3' untranslated region. |
1997 |
Mol. Cell. Biol. |
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Effects of vinconate on age-related alterations in [3H]MK-801, [3H]glycine, sodium-dependent D-[3H]aspartate, [3H]FK-506 and [3H]PN200-110 binding in rats. |
1997 |
Mech. Ageing Dev. |
pmid:9152958
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Effect of hematocrit and albumin concentration on hepatic clearance of tacrolimus (FK506) during rabbit liver perfusion. |
1997 |
Drug Metab. Dispos. |
pmid:9152601
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Autoimmune enteropathy in a pediatric patient: partial response to tacrolimus therapy. |
1997 |
Clin Pediatr (Phila) |
pmid:9152557
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Living related partial liver transplantation in biliary atresia: 11 cases of experience. |
1997 |
Tohoku J. Exp. Med. |
pmid:9149348
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Preliminary report on the use of oral tacrolimus (FK506) in the treatment of complicated proximal small bowel and fistulizing Crohn's disease. |
1997 |
Am. J. Gastroenterol. |
pmid:9149205
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Wong PW and Pessah IN |
Noncoplanar PCB 95 alters microsomal calcium transport by an immunophilin FKBP12-dependent mechanism. |
1997 |
Mol. Pharmacol. |
pmid:9145907
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Template-based docking of a prolactin receptor proline-rich motif octapeptide to FKBP12: implications for cytokine receptor signaling. |
1997 |
Protein Sci. |
pmid:9144770
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Jun NH2-terminal kinase is constitutively activated in T cells transformed by the intracellular parasite Theileria parva. |
1997 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9144200
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Calcineurin inhibitor, FK506, prevents reduction in the binding capacity of cyclic AMP-dependent protein kinase in ischemic gerbil brain. |
1997 |
J. Cereb. Blood Flow Metab. |
pmid:9143223
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Control of inflammatory damage by anti-LFA-1: increase success of myoblast transplantation. |
1997 Mar-Apr |
Cell Transplant |
pmid:9142441
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Early pharmacokinetic profiles of enteral tacrolimus after multivisceral transplantation. |
1997 |
Transplant. Proc. |
pmid:9142303
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Pharmacokinetics of FK506 and mycophenolic acid in experimental and clinical intestinal transplantation. |
1997 |
Transplant. Proc. |
pmid:9142302
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Combined orthotopic liver-small bowel transplantation or small bowel transplantation in pigs: relations between survival, rejection, and mucosal morphometry. |
1997 |
Transplant. Proc. |
pmid:9142295
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Intestinal damage evaluation in swine allograft small bowel through hyaluronic acid quantification. |
1997 |
Transplant. Proc. |
pmid:9142293
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Tacrolimus and mycophenolate mofetil in pig small bowel transplantation: different protocols and their outcome. |
1997 |
Transplant. Proc. |
pmid:9142286
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Small bowel transplantation under oral immunosuppression: experimental study in the pig. |
1997 |
Transplant. Proc. |
pmid:9142285
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Complement activation during rejection in experimental intestinal transplantation. |
1997 |
Transplant. Proc. |
pmid:9142282
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Small bowel myoelectrical activity after transplantation in pigs: motility versus ACR score. |
1997 |
Transplant. Proc. |
pmid:9142281
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Vascularized bone marrow allotransplantation in rats prolongs a simultaneous skin allograft. |
1997 |
Transplant. Proc. |
pmid:9142252
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Azuma H et al. |
Atypical Epstein-Barr virus infection during and after intermittent FK506 therapy. |
1997 |
Acta Paediatr Jpn |
pmid:9141259
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Landström M and Funa K |
Apoptosis in rat prostatic adenocarcinoma is associated with rapid infiltration of cytotoxic T-cells and activated macrophages. |
1997 |
Int. J. Cancer |
pmid:9139883
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[The role of endothelin in the physiology and pathophysiology of the circulatory system and kidneys]. |
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Pol. Arch. Med. Wewn. |
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Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function. |
1997 |
Curr. Biol. |
pmid:9133345
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Transient diabetes mellitus and peripheral insulin resistance following Tacrolimus intoxication in a child after renal transplantation. |
1997 |
Nephrol. Dial. Transplant. |
pmid:9132657
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Pratt WB |
The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase. |
1997 |
Annu. Rev. Pharmacol. Toxicol. |
pmid:9131255
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Karlsson H et al. |
Energy levels in resting and mitogen-stimulated human lymphocytes during treatment with FK506 or cyclosporin A in vitro. |
1997 |
Biochim. Biophys. Acta |
pmid:9131051
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Chemotaxis of macrophages by a peritoneal fluid protein in women with endometriosis. |
1997 |
Fertil. Steril. |
pmid:9130891
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Population pharmacokinetics of sirolimus in kidney transplant patients. |
1997 |
Clin. Pharmacol. Ther. |
pmid:9129559
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Immunophilins, ligands, and the control of signal transduction. |
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Harvey Lect. |
pmid:9127988
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Identification of a 37 kDa tacrolimus, sirolimus and cyclosporine binding immunophilin possessing glyceraldehyde 3-phosphate dehydrogenase activity isolated from the Jurkat T cell line. |
1997 |
Clin. Biochem. |
pmid:9127694
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Mondragon A et al. |
Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center. |
1997 |
Biochemistry |
pmid:9125515
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Yamagami S et al. |
Rejection mechanism and immunosuppression by FK 506 and anti-leukocyte function associated antigen-1 antibody in concordant corneal xenotransplantation. |
1997 Feb-Mar |
Transplant. Proc. |
pmid:9123598
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Ohdan H et al. |
Prolongation of hamster-to-rat liver xenograft survival by donor bone marrow augmentation. |
1997 Feb-Mar |
Transplant. Proc. |
pmid:9123589
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Matsumiya G et al. |
Serum interleukin-6 level after cardiac xenotransplantation in primates. |
1997 Feb-Mar |
Transplant. Proc. |
pmid:9123586
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Troppmann C et al. |
FK 506 versus cyclosporine A for steroid-free synergistic combination therapy with rapamycin in a discordant large animal donor xenoislet transplant model. |
1997 Feb-Mar |
Transplant. Proc. |
pmid:9123585
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Batten P et al. |
Effect of cyclosporine A and FK 506 on human T cell responses to xenogeneic and allogeneic endothelium: relative resistance of T cell/porcine endothelial interactions. |
1997 Feb-Mar |
Transplant. Proc. |
pmid:9123582
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Mycophenolic acid in combination with FK 506: a pharmacokinetic study in piglets after small-bowel transplantation. |
1997 Feb-Mar |
Transplant. Proc. |
pmid:9123489
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Experimental animal model of graft-versus-host disease (GVHD) after small-bowel transplantation: characteristics of the model and application to developing treatment strategies. |
1997 Feb-Mar |
Transplant. Proc. |
pmid:9123488
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Morphological and functional changes in small-bowel allografts of pigs under combined tacrolimus and mycophenolate mofetil immunosuppression. |
1997 Feb-Mar |
Transplant. Proc. |
pmid:9123483
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