tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Gastrointestinal Diseases D005767 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Brain Edema D001929 20 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
HIV Infections D015658 20 associated lipids
Anemia D000740 21 associated lipids
Vomiting D014839 21 associated lipids
Hyperglycemia D006943 21 associated lipids
Bacterial Infections D001424 21 associated lipids
Hypersensitivity D006967 22 associated lipids
Erythema D004890 22 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Cholestasis D002779 23 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Fibrosis D005355 23 associated lipids
Cystitis D003556 23 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Cho EJ et al. Performance of the Dimension TAC assay and comparison of multiple platforms for the measurement of tacrolimus. 2018 J. Clin. Lab. Anal. pmid:29148096
Cheng CY et al. Intervention of Online Percent Coefficient of Variation Reporting System Reduces the Variability of Tacrolimus Trough Concentration in Kidney Transplant Recipients. 2018 Transplant. Proc. pmid:30316366
Loeschenberger B et al. Calcineurin inhibitor-induced complement system activation via ERK1/2 signalling is inhibited by SOCS-3 in human renal tubule cells. 2018 Eur. J. Immunol. pmid:29143318
Shimoda-Komatsu Y et al. Chronological observation of surgically-treated granuloma faciale implies the necessity of circumspect management for perinasal nodular subset. 2018 J. Dermatol. pmid:29905388
Hou Y et al. Management of hepatic vein occlusive disease after liver transplantation: A case report with literature review. 2018 Medicine (Baltimore) pmid:29901618
Liu HY et al. Ribavirin-induced anaemia reduced tacrolimus level in a hepatitis C patient receiving haemodialysis. 2018 BMJ Case Rep pmid:29669765
Majeed A et al. A 20-year experience with nocardiosis in solid organ transplant (SOT) recipients in the Southwestern United States: A single-center study. 2018 Transpl Infect Dis pmid:29668074
Shi D et al. CYP3A4 and GCK genetic polymorphisms are the risk factors of tacrolimus-induced new-onset diabetes after transplantation in renal transplant recipients. 2018 Eur. J. Clin. Pharmacol. pmid:29546446
Song JL et al. Higher tacrolimus blood concentration is related to increased risk of post-transplantation diabetes mellitus after living donor liver transplantation. 2018 Int J Surg pmid:29360611
Charnaya O et al. Results of early treatment for de novo donor-specific antibodies in pediatric kidney transplant recipients in a cross-sectional and longitudinal cohort. 2018 Pediatr Transplant pmid:29356221