Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Laskow DA et al. | The role of tacrolimus in adult kidney transplantation: a review. | 1998 | Clin Transplant | pmid:9850440 |
Nishida S et al. | Allograft rejection of small bowel transplantation in pigs. | 1998 | Surg. Today | pmid:9851621 |
Gammie JS et al. | Tacrolimus-based partial conditioning produces stable mixed lymphohematopoietic chimerism and tolerance for cardiac allografts. | 1998 | Circulation | pmid:9852899 |
Pou L et al. | Therapeutic drug monitoring of tacrolimus in liver transplantation, phase III FK506 multicenter Spanish Study Group: a two-year follow-up. | 1998 | Ther Drug Monit | pmid:9853973 |
Brunet M et al. | Multicenter comparison of first- and second-generation IMx tacrolimus microparticle enzyme immunoassays in liver and kidney transplantation. | 1998 | Ther Drug Monit | pmid:9853987 |
Hatori M et al. | Clinical and histopathologic examination of renal allografts treated with tacrolimus (FK506) for at least one year. | 1998 | Int. J. Urol. | pmid:9855119 |
Olyaei AJ et al. | Interaction between tacrolimus and nefazodone in a stable renal transplant recipient. | 1998 Nov-Dec | Pharmacotherapy | pmid:9855339 |
Hamilton GS and Steiner JP | Immunophilins: beyond immunosuppression. | 1998 | J. Med. Chem. | pmid:9857082 |
Paul C and Ho VC | Ascomycins in dermatology. | 1998 | Semin Cutan Med Surg | pmid:9859912 |
Shapiro VS et al. | Nuclear factor of activated T cells and AP-1 are insufficient for IL-2 promoter activation: requirement for CD28 up-regulation of RE/AP. | 1998 | J. Immunol. | pmid:9862666 |
Maggi U et al. | Hepatitis B and C virus-induced diseases and acute rejection after liver transplantation. | 1998 | Transplant. Proc. | pmid:9865255 |
Opelz G | Evaluation of immunosuppressive induction regimens in renal transplantation. Collaborative Transplant Study. | 1998 | Transplant. Proc. | pmid:9865286 |
Moffatt SD et al. | Comparative efficacy of liposomal FK506 with FK506. | 1998 | Transplant. Proc. | pmid:9865297 |
Brunet M et al. | Therapeutic drug monitoring of tacrolimus in kidney transplantation: 9-month follow-up. | 1998 | Transplant. Proc. | pmid:9865298 |
Fleck PR et al. | Tacrolimus use in kidney-pancreas recipients is associated with less acute renal dysfunction than cyclosporine. | 1998 | Transplant. Proc. | pmid:9865299 |
du Toit DF et al. | Tacrolimus (FK506) monotherapy provides potent and significant suppression of allogeneic foetal rat pancreatic allograft rejection. | 1998 | Transplant. Proc. | pmid:9865300 |
Daoud AJ et al. | A comparison of the safety and efficacy of mycophenolate mofetil, prednisone and cyclosporine and mycophenolate mofetil, and prednisone and tacrolimus. | 1998 | Transplant. Proc. | pmid:9865303 |
Braun F et al. | How to handle mycophenolate mofetil in combination with tacrolimus? | 1998 | Transplant. Proc. | pmid:9865309 |
Schorlemmer HU et al. | Long-term allograft survival and tolerance induction by the synergistic activity of malononitrilamides and tacrolimus. | 1998 | Transplant. Proc. | pmid:9865312 |
Metcalfe SM et al. | In vitro transcription and translation of the tumour suppressor protein P53: qualitative and quantitative effects of FK506 and rapamycin. | 1998 | Transplant. Proc. | pmid:9865315 |