tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Ventricular Dysfunction, Left D018487 33 associated lipids
Cryptogenic Organizing Pneumonia D018549 3 associated lipids
Hypoplastic Left Heart Syndrome D018636 1 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Multiple Endocrine Neoplasia Type 2a D018813 1 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Fasciitis, Necrotizing D019115 1 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Oral Ulcer D019226 1 associated lipids
Endotoxemia D019446 27 associated lipids
Pouchitis D019449 3 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Hepatitis, Autoimmune D019693 1 associated lipids
Hepatitis B, Chronic D019694 4 associated lipids
Hepatitis C, Chronic D019698 12 associated lipids
Miller Fisher Syndrome D019846 1 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Per page 10 20 50 100 | Total 613

PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Florio G et al. The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils. 2000 AIDS pmid:10853974
Nowak P et al. Follow-up of antiretroviral treatment in liver transplant recipients with primary and chronic HIV type 1 infection. 2003 AIDS Res. Hum. Retroviruses pmid:12581512
Sklar EM Post-transplant neurotoxicity: what role do calcineurin inhibitors actually play? 2006 AJNR Am J Neuroradiol pmid:16971594
Bargalló N et al. Cortical laminar necrosis caused by immunosuppressive therapy and chemotherapy. 2000 AJNR Am J Neuroradiol pmid:10730638
Bartynski WS et al. Etiology of cortical and white matter lesions in cyclosporin-A and FK-506 neurotoxicity. 2001 Nov-Dec AJNR Am J Neuroradiol pmid:11733324
Bartynski WS et al. Pretransplantation conditioning influence on the occurrence of cyclosporine or FK-506 neurotoxicity in allogeneic bone marrow transplantation. 2004 AJNR Am J Neuroradiol pmid:14970028
Bartynski WS et al. Posterior reversible encephalopathy syndrome after solid organ transplantation. 2008 AJNR Am J Neuroradiol pmid:18272559
Schuuring J et al. Severe tacrolimus leukoencephalopathy after liver transplantation. 2003 Nov-Dec AJNR Am J Neuroradiol pmid:14625238
Oliverio PJ et al. Reversible tacrolimus-induced neurotoxicity isolated to the brain stem. 2000 AJNR Am J Neuroradiol pmid:10954277
Appignani BA et al. Neuroimaging findings in patients on immunosuppressive therapy: experience with tacrolimus toxicity. 1996 AJR Am J Roentgenol pmid:8623651
Landy J and Hart AL Commentary: short-term efficacy of tacrolimus in steroid-refractory ulcerative colitis. 2013 Aliment. Pharmacol. Ther. pmid:23336680
Hirai F et al. Letter: short-term efficacy of tacrolimus in steroid-refractory ulcerative colitis. 2013 Aliment. Pharmacol. Ther. pmid:23336690
Schmidt KJ et al. Letter: short-term efficacy of tacrolimus in steroid-refractory ulcerative colitis - authors' reply. 2013 Aliment. Pharmacol. Ther. pmid:23336691
Yamamoto T et al. Tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis: a retrospective observational study. 2016 Aliment. Pharmacol. Ther. pmid:26762838
Travis S Review article: saving the colon in severe colitis - the case for medical therapy. 2006 Aliment. Pharmacol. Ther. pmid:16961749
Schmidt KJ et al. Short-term efficacy of tacrolimus in steroid-refractory ulcerative colitis - experience in 130 patients. 2013 Aliment. Pharmacol. Ther. pmid:23121200
McSharry K et al. Systematic review: the role of tacrolimus in the management of Crohn's disease. 2011 Aliment. Pharmacol. Ther. pmid:21999607
Nakase H et al. Tacrolimus suppresses IL-12/IL23 p40 in Crohn's disease and heals fistulae refractory to anti-TNF-α therapy. 2011 Aliment. Pharmacol. Ther. pmid:21434949
Nakase H et al. Tacrolimus: rescue therapy or experimental drug for severe ulcerative colitis? 2011 Aliment. Pharmacol. Ther. pmid:21198700
Mehta SJ et al. Review article: strategies for the management of chronic unremitting ulcerative colitis. 2013 Aliment. Pharmacol. Ther. pmid:23718288