tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Waer M | New immunosuppressive agents for organ transplantation. | 1997 | Acta Clin Belg | pmid:9351290 |
| Liang J et al. | Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. | 1999 | Acta Crystallogr. D Biol. Crystallogr. | pmid:10089303 |
| Bracher A et al. | Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. | 2011 | Acta Crystallogr. D Biol. Crystallogr. | pmid:21636895 |
| Li P et al. | Structure of the N-terminal domain of human FKBP52. | 2003 | Acta Crystallogr. D Biol. Crystallogr. | pmid:12499534 |
| Schreier MH | Immunophilins and immunosuppression by cyclosporins and macrolide structures. | 1994 | Acta Derm Venereol Suppl (Stockh) | pmid:7521103 |
| Quist SR et al. | Effects of Topical Tacrolimus and Polyunsaturated Fatty Acids on In Vivo Release of Eicosanoids in Atopic Dermatitis During Dermal Microdialysis. | 2016 | Acta Derm. Venereol. | pmid:26911315 |
| de la Rosa Carrillo D and Christensen OB | Treatment of chronic discoid lupus erythematosus with topical tacrolimus. | 2004 | Acta Derm. Venereol. | pmid:15202845 |
| Hartmann A et al. | Treatment of generalised vitiligo with tacrolimus 0.1% ointment vs. UVB intense pulsed light phototherapy: a pilot study. | 2014 | Acta Derm. Venereol. | pmid:24473666 |
| Granlund H et al. | Treatment of lichenified atopic eczema with tacrolimus ointment. | 2001 Aug-Sep | Acta Derm. Venereol. | pmid:11720192 |
| Jensen JM et al. | Effects of pimecrolimus compared with triamcinolone acetonide cream on skin barrier structure in atopic dermatitis: a randomized, double-blind, right-left arm trial. | 2013 | Acta Derm. Venereol. | pmid:23571785 |
| Cunha PR | Pimecrolimus cream 1% is effective in seborrhoeic dermatitis refractory to treatment with topical corticosteroids. | 2006 | Acta Derm. Venereol. | pmid:16585998 |
| Cunha PR and Rossi AB | Pimecrolimus cream 1% is effective in a case of granulomatous rosacea. | 2006 | Acta Derm. Venereol. | pmid:16585999 |
| Kirsner RS et al. | Safety and efficacy of tacrolimus ointment versus pimecrolimus cream in the treatment of patients with atopic dermatitis previously treated with corticosteroids. | 2010 | Acta Derm. Venereol. | pmid:20107727 |
| Larsen CG and Thyssen JP | Pustular penile pyoderma gangrenosum successfully treated with topical tacrolimus ointment. | 2012 | Acta Derm. Venereol. | pmid:21681352 |
| Fukamachi S et al. | Therapeutic effectiveness of various treatments for eosinophilic pustular folliculitis. | 2009 | Acta Derm. Venereol. | pmid:19326000 |
| Jacobs F et al. | New approach in combined therapy of perifolliculitis capitis abscedens et suffodiens. | 2011 | Acta Derm. Venereol. | pmid:21681358 |
| Chittock J et al. | Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. | 2015 | Acta Derm. Venereol. | pmid:25594610 |
| Masuda K et al. | Increased levels of serum interleukin-16 in adult type atopic dermatitis. | 2003 | Acta Derm. Venereol. | pmid:12926794 |
| Mrowietz U et al. | An experimental ointment formulation of pimecrolimus is effective in psoriasis without occlusion. | 2003 | Acta Derm. Venereol. | pmid:14609102 |
| Kim TW et al. | Proactive treatment of adult facial seborrhoeic dermatitis with 0.1% tacrolimus ointment: randomized, double-blind, vehicle-controlled, multi-centre trial. | 2013 | Acta Derm. Venereol. | pmid:23388687 |