| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cardiomegaly | D006332 | 31 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Memory Disorders | D008569 | 33 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Glomerulonephritis | D005921 | 35 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
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|---|---|---|---|---|
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| Takeda M et al. | Methotrexate in rescue therapy for xenotransplanted lungs in primates. | 1996 | Transplant. Proc. | pmid:8623402 |
| Maggard M et al. | Incidence of acute rejection in African-American liver transplant recipients. | 1998 | Transplant. Proc. | pmid:9636607 |
| Mueller AR et al. | Influence of immunosuppression on patient outcome after liver transplantation. | 1998 | Transplant. Proc. | pmid:9636608 |
| Yoshida S et al. | Combination therapy with FK 506 and RS61443 for rejection following allogeneic small bowel transplantation in rats. | 2000 | Transplant. Proc. | pmid:11120262 |
| Jordan ML et al. | Outcome of tacrolimus conversion therapy for renal allograft rejection: 5-year follow-up. | 1999 | Transplant. Proc. | pmid:10576052 |
| Nishikawa S et al. | Extended mycophenolate mofetil administration beyond day 30 in allogeneic hematopoietic stem cell transplantation as preemptive therapy for severe graft-versus-host disease. | 2009 | Transplant. Proc. | pmid:19917404 |
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| Marzorati S et al. | Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device. | 2009 Jan-Feb | Transplant. Proc. | pmid:19249555 |
| Kawauchi M et al. | Cardiac xenotransplantation from pig to Japanese monkey with splenectomy, tacrolims, filtration plasmapheresis, and nafamstat mesilate. | 1994 | Transplant. Proc. | pmid:7518105 |
| Platz KP et al. | OKT3 vs FK 506 rescue management of acute steroid-resistant and chronic rejection. | 1995 | Transplant. Proc. | pmid:7533357 |
| Andersson J et al. | The effects of FK 506 on cytokine production are dependent on the mode of cell activation. | 1991 | Transplant. Proc. | pmid:1721311 |
| Wojewodzka J et al. | Inhibition of formation of synapses between dendritic cells and lymphocytes in skin lymph in an allogeneic reaction by cyclosporine and tacrolimus. | 2003 | Transplant. Proc. | pmid:14529947 |
| Suga A et al. | Diabetes mellitus after renal transplantation under tacrolimus-based immunosuppression. | 2003 | Transplant. Proc. | pmid:12591391 |
| Liu B et al. | Single-center experience: tacrolimus and mycophenolate mofetil in early stage of kidney transplantation with liver dysfunction. | 2003 | Transplant. Proc. | pmid:12591396 |
| Koefoed-Nielsen PB et al. | Comparison of the temporal profile of calcineurin inhibition by cyclosporine and tacrolimus in renal transplant patients. | 2005 | Transplant. Proc. | pmid:15919449 |
| Iwahori T et al. | Pharmacokinetic differences between morning and evening administration of cyclosporine and tacrolimus therapy. | 2005 | Transplant. Proc. | pmid:15919450 |
| Tamura K et al. | Inhibition of insulin production by FK 506 is caused at the transcriptional level in pancreatic beta cell when FK BP-12 content is relatively high. | 1995 | Transplant. Proc. | pmid:7533409 |
| Kawano K et al. | Protective effect of FK 506 on hepatic injury following cold ischemic preservation and transplantation: influence on hepatic microcirculation. | 1995 | Transplant. Proc. | pmid:7533410 |
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| Varo E et al. | Cardiovascular risk factors in liver allograft recipients: relationship with immunosuppressive therapy. | 2002 | Transplant. Proc. | pmid:12176481 |
| Odoul F et al. | Massive ingestion of tacrolimus in a young liver transplant patient. | 1998 | Transplant. Proc. | pmid:9865375 |
| Weber M et al. | Decreased rejection episodes in African-American renal transplant recipients receiving mycophenolate mofetil/tacrolimus therapy. | 1997 | Transplant. Proc. | pmid:9414883 |
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| Jiménez O et al. | Defining the initial doses of sirolimus and tacrolimus in the period immediately after renal transplantation. | 2003 | Transplant. Proc. | pmid:12962758 |
| Ciftci HS et al. | Effect of MDR1 polymorphisms on the blood concentrations of tacrolimus in Turkish renal transplant patients. | 2013 | Transplant. Proc. | pmid:23622581 |
| Cotovio P et al. | New-onset diabetes after transplantation: assessment of risk factors and clinical outcomes. | 2013 | Transplant. Proc. | pmid:23622631 |
| Cronin DC et al. | Tacrolimus therapy for refractory renal allograft rejection: experience with steroid withdrawal. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123010 |
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| Teebken OE et al. | Primary immunosuppression with tacrolimus and mycophenolate mofetil versus cyclosporine and azathioprine in heart transplant recipients. | 2002 | Transplant. Proc. | pmid:12072335 |
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| Personett HA et al. | Impact of molecular adsorbent recirculating system therapy on tacrolimus elimination: a case report. | 2014 | Transplant. Proc. | pmid:25017243 |
| Grochowicz PM et al. | Synergistic interaction between castanospermine and tacrolimus in a rat heart allograft model. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123296 |
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| Gerbase MW et al. | Low doses of mycophenolate mofetil with low doses of tacrolimus prevent acute rejection and long-term function loss after lung transplantation. | 2001 | Transplant. Proc. | pmid:11377481 |
| Yussim A et al. | Conversion from cyclosporine to tacrolimus in hepatic and renal transplantation. | 1996 | Transplant. Proc. | pmid:8962233 |
| Gerhardt U et al. | High QT dispersion in tacrolimus-treated kidney transplant recipients. | 2001 | Transplant. Proc. | pmid:11377482 |
| Golling M et al. | Tacrolimus reduction improves glucose metabolism and insulin secretion after liver transplantation. | 1996 | Transplant. Proc. | pmid:8962234 |
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