Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Takagishi K et al. | Effects of FK-506 on collagen arthritis in mice. | 1989 | Transplant. Proc. | pmid:2468205 |
Arita C et al. | Effect of FK 506 (FR 900506) on collagen arthritis in rats: a preliminary report. | 1989 | Transplant. Proc. | pmid:2468206 |
Morimoto T et al. | Blood levels of FK506 after intramuscular and intravenous administration in dogs. | 1989 | Transplant. Proc. | pmid:2468207 |
Siekierka JJ et al. | A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. | 1989 | Nature | pmid:2477714 |
Harding MW et al. | A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. | 1989 | Nature | pmid:2477715 |
Inamura N et al. | Immunosuppressive effect of FK506 on collagen-induced arthritis in rats. | 1988 | Clin. Immunol. Immunopathol. | pmid:2446810 |
Inamura N et al. | Prolongation of skin allograft survival in rats by a novel immunosuppressive agent, FK506. | 1988 | Transplantation | pmid:2447690 |
Ochiai T et al. | Studies on FK506 in experimental organ transplantation. | 1988 | Transplant. Proc. | pmid:2450414 |
Immunosuppression: FK506. | 1988 | Transplant. Proc. | pmid:2450415 | |
Todo S et al. | Effect of FK506 in experimental organ transplantation. | 1988 | Transplant. Proc. | pmid:2450416 |
Tsuchimoto S et al. | [Orthotopic liver transplantation in the rat--immunosuppressive effect of FR100906 on the survival of liver allografts]. | 1988 | Nihon Geka Gakkai Zasshi | pmid:2452341 |
Nakajima K et al. | Prolongation of cardiac xenograft survival in rats treated with 15-deoxyspergualin alone and in combination with FK506. | 1988 | Transplantation | pmid:2454521 |
Todo S et al. | Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction. | 1988 | Surgery | pmid:2456627 |
Kawashima H et al. | Effects of a new immunosuppressive agent, FK506, on experimental autoimmune uveoretinitis in rats. | 1988 | Invest. Ophthalmol. Vis. Sci. | pmid:2458329 |
Warty V et al. | FK506: a novel immunosuppressive agent. Characteristics of binding and uptake by human lymphocytes. | 1988 | Transplantation | pmid:2458643 |
Hewitt CW and Black KS | Comparative studies of FK506 with cyclosporine. | 1988 | Transplantation | pmid:2458644 |
Woo J et al. | Spleen lymphocyte populations and expression of activation markers in rats treated with the potent new immunosuppressive agent FK-506. | 1988 | Immunology | pmid:2460401 |
Hatanaka H et al. | FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physico-chemical and biological characteristics. | 1988 | J. Antibiot. | pmid:2461926 |
Inamura N et al. | Immunosuppressive effect of FK506 on experimental allergic encephalomyelitis in rats. | 1988 | Int. J. Immunopharmacol. | pmid:2463974 |
Hatanaka H et al. | FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. I. Taxonomy of the producing strain. | 1988 | J. Antibiot. | pmid:3198493 |