tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Azuma H et al. | Atypical Epstein-Barr virus infection during and after intermittent FK506 therapy. | 1997 | Acta Paediatr Jpn | pmid:9141259 |
| Bienemann K et al. | Topical tacrolimus is effective against eczema in Wiskott-Aldrich syndrome (WAS). | 2007 | Acta Paediatr. | pmid:17429928 |
| Sinha R and Marks SD | Tacrolimus toxicity secondary to diarrhoea in nephrotic syndrome. | 2013 | Acta Paediatr. | pmid:23573873 |
| Isidor B et al. | Hyperzincemia and hypercalprotectinemia: unsuccessful treatment with tacrolimus. | 2009 | Acta Paediatr. | pmid:18983438 |
| Marlaka JR et al. | Tacrolimus without or with the addition of conventional immunosuppressive treatment in juvenile autoimmune hepatitis. | 2012 | Acta Paediatr. | pmid:22646819 |
| Gradman J and Wolthers OD | Short-term growth in children with eczema during treatment with topical mometasone furoate and tacrolimus. | 2007 | Acta Paediatr. | pmid:17590198 |
| Puzik A et al. | Effects of ciclosporin A, tacrolimus and sirolimus on cytokine production in neonatal immune cells. | 2007 | Acta Paediatr. | pmid:17880416 |
| Zhang FM et al. | Effects of tacrolimus on infection of Friend murine leukemia virus to Fv-4 gene heterozygous mice. | 2004 | Acta Pharmacol. Sin. | pmid:14769211 |
| Liu S et al. | The POR rs1057868-rs2868177 GC-GT diplotype is associated with high tacrolimus concentrations in early post-renal transplant recipients. | 2016 | Acta Pharmacol. Sin. | pmid:27498776 |
| Yu Y et al. | Electrophysiological actions of cyclosporin A and tacrolimus on rat hippocampal CA1 pyramidal neurons. | 2007 | Acta Pharmacol. Sin. | pmid:18031601 |