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LCPT once-daily extended-release tacrolimus tablets versus twice-daily capsules: a pooled analysis of two phase 3 trials in important de novo and stable kidney transplant recipient subgroups. |
2016 |
Transpl. Int. |
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van der Schaft J et al. |
First experience with extended release tacrolimus in the treatment of adult patients with severe, difficult to treat atopic dermatitis: Clinical efficacy, safety and dose finding. |
2016 |
J. Dermatol. Sci. |
pmid:26547110
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Gokhale NS |
Systematic approach to managing vernal keratoconjunctivitis in clinical practice: Severity grading system and a treatment algorithm. |
2016 |
Indian J Ophthalmol |
pmid:27050351
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GvHD prophylaxis with tacrolimus plus sirolimus after reduced intensity conditioning allogeneic transplantation: results of a multicenter study. |
2016 |
Bone Marrow Transplant. |
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Management of refractory autoimmune hemolytic anemia via allogeneic stem cell transplantation. |
2016 |
Bone Marrow Transplant. |
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The impact of directly acting antivirals on the enzymatic liver function of liver transplant recipients with recurrent hepatitis C. |
2016 |
Transpl Infect Dis |
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Nakamura H et al. |
Usefulness of tacrolimus for refractory adult-onset still's disease: Report of six cases. |
2016 |
Mod Rheumatol |
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Tacrolimus-loaded nanostructured lipid carriers for oral delivery-in vivo bioavailability enhancement. |
2016 |
Eur J Pharm Biopharm |
pmid:27793753
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Wen Y et al. |
Tacrolimus restores podocyte injury and stabilizes the expression of Cabin1 in 5/6 nephrectomized rats. |
2016 |
Ren Fail |
pmid:26905810
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Challenging immunosuppression treatment in lung transplant recipients with kidney failure. |
2016 |
Transpl. Immunol. |
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Has widespread use of biologic and immunosuppressant therapy for ulcerative colitis affected surgical trends? Results of a questionnaire survey of surgical institutions in Japan. |
2016 |
Surg. Today |
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A prospective randomized trial comparing cyclosporine/methotrexate and tacrolimus/sirolimus as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell transplantation. |
2016 |
Haematologica |
pmid:27662016
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Within-Patient Variability in Tacrolimus Blood Levels Predicts Kidney Graft Loss and Donor-Specific Antibody Development. |
2016 |
Transplantation |
pmid:26703349
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FkbN and Tcs7 are pathway-specific regulators of the FK506 biosynthetic gene cluster in Streptomyces tsukubaensis L19. |
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J. Ind. Microbiol. Biotechnol. |
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A preliminary study searching for the right dose of tacrolimus in very young (≤4 years) renal transplant patients. |
2016 |
J. Pharm. Pharmacol. |
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Results of a 2-arm, phase 2 clinical trial using post-transplantation cyclophosphamide for the prevention of graft-versus-host disease in haploidentical donor and mismatched unrelated donor hematopoietic stem cell transplantation. |
2016 |
Cancer |
pmid:27404668
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Tracking protein-protein interaction and localization in living cells using a high-affinity molecular binder. |
2016 |
Biochem. Biophys. Res. Commun. |
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Tacrolimus suppresses atopic dermatitis-associated cytokines and chemokines in monocytes. |
2016 |
J Microbiol Immunol Infect |
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Population Pharmacokinetic Modelling and Bayesian Estimation of Tacrolimus Exposure: Is this Clinically Useful for Dosage Prediction Yet? |
2016 |
Clin Pharmacokinet |
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Hyaluronic acid-coated niosomes facilitate tacrolimus ocular delivery: Mucoadhesion, precorneal retention, aqueous humor pharmacokinetics, and transcorneal permeability. |
2016 |
Colloids Surf B Biointerfaces |
pmid:26820107
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Tacrolimus and oral lichen planus. Possible absorption after mucosal application? |
2016 |
J Eur Acad Dermatol Venereol |
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Comparison of the therapeutic efficacy and safety between tacrolimus and infliximab for moderate-to-severe ulcerative colitis: a single center experience. |
2016 |
Scand. J. Gastroenterol. |
pmid:26818468
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Clinical study of double dose of valsartan combined with tacrolimus in treatment of diabetic nephropathy. |
2016 |
Eur Rev Med Pharmacol Sci |
pmid:26813471
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Therapeutic Effect of 0.1% Topical Tacrolimus for Childhood Interstitial Keratitis Refractory to Cyclosporine. |
2016 |
J Nippon Med Sch |
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Paclitaxel and Tacrolimus Coencapsulated Polymeric Micelles That Enhance the Therapeutic Effect of Drug-Resistant Ovarian Cancer. |
2016 |
ACS Appl Mater Interfaces |
pmid:26809267
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Annular Lichenoid Dermatitis of Youth: A Chronic Case Managed Using Pimecrolimus. |
2016 |
Pediatr Dermatol |
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Experimental Studies on Protective Effects of FK506 Against Hepatic Ischemia-Reperfusion Injury. |
2016 |
J. Med. Invest. |
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Chimeric Allografts Induced by Short-Term Treatment With Stem Cell-Mobilizing Agents Result in Long-Term Kidney Transplant Survival Without Immunosuppression: A Study in Rats. |
2016 |
Am. J. Transplant. |
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Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of psoriasis. |
2016 |
J Control Release |
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Chimeric Allografts Induced by Short-Term Treatment With Stem Cell Mobilizing Agents Result in Long-Term Kidney Transplant Survival Without Immunosuppression: II, Study in Miniature Swine. |
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Am. J. Transplant. |
pmid:26748958
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Quantitative analysis of tissue inflammation and responses to treatment in immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome, and review of literature. |
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J Microbiol Immunol Infect |
pmid:26748735
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Vitamin D status and the effects of oral vitamin D treatment in children with vitiligo: A prospective study. |
2016 |
Clin Nutr ESPEN |
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Oral tacrolimus oil formulations for enhanced lymphatic delivery and efficient inhibition of T-cell's interleukin-2 production. |
2016 |
Eur J Pharm Biopharm |
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[Tacrolimus-induced gynecomastia in a patient with polymyositis]. |
2016 |
Med Clin (Barc) |
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Protective effect of mycophenolate mofetil against nephrotoxicity and hepatotoxicity induced by tacrolimus in Wistar rats. |
2016 |
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Granulocyte Colony-Stimulating Factor-Mobilized Allografts Contain Activated Immune Cell Subsets Associated with Risk of Acute and Chronic Graft-versus-Host Disease. |
2016 |
Biol. Blood Marrow Transplant. |
pmid:26743340
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Developmental changes of MPA exposure in children. |
2016 |
Pediatr. Nephrol. |
pmid:26743220
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A candidate gene approach of the calcineurin pathway to identify variants associated with clinical outcomes in renal transplantation. |
2016 |
Pharmacogenomics |
pmid:26894651
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Analytical Validation and Cross-Validation of an NFAT-Regulated Gene Expression Assay for Pharmacodynamic Monitoring of Therapy With Calcineurin Inhibitors. |
2016 |
Ther Drug Monit |
pmid:27661400
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Comparative clinical evaluation of tacrolimus and cyclosporine eye drops for the treatment of canine keratoconjunctivitis sicca. |
2016 |
Acta Vet. Hung. |
pmid:27653428
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Design and rationale of the ATHENA study--A 12-month, multicentre, prospective study evaluating the outcomes of a de novo everolimus-based regimen in combination with reduced cyclosporine or tacrolimus versus a standard regimen in kidney transplant patients: study protocol for a randomised controlled trial. |
2016 |
Trials |
pmid:26888217
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Conversion to Once-Daily Tacrolimus Results in Increased p38MAPK Phosphorylation in T Lymphocytes of Kidney Transplant Recipients. |
2016 |
Ther Drug Monit |
pmid:26606072
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Nanocomposite microparticles (nCmP) for the delivery of tacrolimus in the treatment of pulmonary arterial hypertension. |
2016 |
Int J Pharm |
pmid:27568494
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Vesicular eruption in a 2-year-old boy. |
2016 |
J Fam Pract |
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Tacrolimus for children with refractory nephrotic syndrome: a one-year prospective, multicenter, and open-label study of Tacrobell®, a generic formula. |
2016 |
World J Pediatr |
pmid:26684309
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Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation. |
2016 |
Health Technol Assess |
pmid:27557331
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Tsuji T et al. |
Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice. |
2016 |
Allergol Int |
pmid:26666476
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Ishiwata Y et al. |
Effects of Miconazole Oral Gel on Blood Concentrations of Tacrolimus and Cyclosporine: A Retrospective Observational Study. |
2016 |
Ther Drug Monit |
pmid:27559841
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Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles. |
2016 |
Biomed. Pharmacother. |
pmid:26898446
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Tacrolimus Metabolite M-III May Have Nephrotoxic and Myelotoxic Effects and Increase the Incidence of Infections in Kidney Transplant Recipients. |
2016 |
Transplant. Proc. |
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Evaluation of the New Siemens Tacrolimus Assay on the Dimension EXL Integrated Chemistry System Analyzer: Comparison With an Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method. |
2016 |
Ther Drug Monit |
pmid:27494947
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A Case Report of Drug-Induced Thrombocytopenia after Living Donor Liver Transplantation. |
2016 |
Kobe J Med Sci |
pmid:27492209
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Phosphatase inhibition increases AQP2 accumulation in the rat IMCD apical plasma membrane. |
2016 |
Am. J. Physiol. Renal Physiol. |
pmid:27488997
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Periorbital erythema following alcohol ingestion during treatment with topical tacrolimus. |
2016 |
CMAJ |
pmid:26598374
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Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. |
2016 |
J. Med. Invest. |
pmid:27644556
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Congenital Infections in Neonates of Women With Liver or Kidney Transplants. |
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Transplant. Proc. |
pmid:27496446
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Lowering of Messenger Ribonucleic Acid Toll-Like Receptors 2-4,9 in Peripheral Blood Mononuclear Cells in Kidney Allograft Recipients, Relationships With Immunosuppressive Treatment, and Delayed Graft Function Occurrence. |
2016 |
Transplant. Proc. |
pmid:27496439
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Adrenomedullin Therapy in Patients with Refractory Ulcerative Colitis: A Case Series. |
2016 |
Dig. Dis. Sci. |
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Umbilical cord blood transplantation for adults using tacrolimus with two-day very-short-term methotrexate for graft-versus-host disease prophylaxis. |
2016 |
Leuk. Res. |
pmid:27376545
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Betamethasone, but Not Tacrolimus, Suppresses the Development of Th2 Cells Mediated by Langerhans Cell-Like Dendritic Cells. |
2016 |
Biol. Pharm. Bull. |
pmid:27374298
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Kimsa M et al. |
Transforming growth factor β-related genes in human retinal pigment epithelial cells after tacrolimus treatment. |
2016 |
Pharmacol Rep |
pmid:27372923
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Systemic Absorption of Topical Tacrolimus in Metastatic Crohn Disease With Skin Ulcers. |
2016 |
Actas Dermosifiliogr |
pmid:27372545
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Gray JM and Ameduri RK |
Tacrolimus-associated hemolytic uremic syndrome in a pediatric heart transplant recipient. |
2016 |
Pediatr Transplant |
pmid:27371345
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Tanriover B et al. |
Acute Rejection Rates and Graft Outcomes According to Induction Regimen among Recipients of Kidneys from Deceased Donors Treated with Tacrolimus and Mycophenolate. |
2016 |
Clin J Am Soc Nephrol |
pmid:27364616
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Successful multi-target therapy using corticosteroid, tacrolimus, cyclophosphamide, and rituximab for rapidly progressive interstitial lung disease in a patient with clinically amyopathic dermatomyositis. |
2016 |
Mod Rheumatol |
pmid:25698368
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Vignali D et al. |
IL-7 Mediated Homeostatic Expansion of Human CD4+CD25+FOXP3+ Regulatory T Cells After Depletion With Anti-CD25 Monoclonal Antibody. |
2016 |
Transplantation |
pmid:27306531
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Efficacy and Safety of Grapefruit Juice Intake Accompanying Tacrolimus Treatment in Connective Tissue Disease Patients. |
2016 |
Intern. Med. |
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Cysteamine in renal transplantation: A report of two patients with nephropathic cystinosis and the successful re-initiation of cysteamine therapy during the immediate post-transplant period. |
2016 |
Pediatr Transplant |
pmid:26477696
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Saitman A et al. |
Evaluation of the Waters MassTrak LC-MS/MS Assay for Tacrolimus and a Comparison to the Abbott Architect Immunoassay. |
2016 |
Ther Drug Monit |
pmid:26473523
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Metzker M et al. |
Analytical evaluation of a real-time PCR-based DNA demethylation assay to assess the frequency of naturally occurring regulatory T cells in peripheral blood. |
2016 |
Clin. Biochem. |
pmid:27220060
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Pharmacokinetics of prolonged-release tacrolimus and implications for use in solid organ transplant recipients. |
2016 |
Clin Transplant |
pmid:27220013
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Effects of CYP3A5 polymorphism on the pharmacokinetics of a once-daily modified-release tacrolimus formulation and acute kidney injury in hematopoietic stem cell transplantation. |
2016 |
Cancer Chemother. Pharmacol. |
pmid:27217047
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Narain S and Furie R |
Update on clinical trials in systemic lupus erythematosus. |
2016 |
Curr Opin Rheumatol |
pmid:27314466
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Tremblay S et al. |
Absence of the Effect of Pretransplant Body Mass Index on Post Kidney Transplant Outcomes. |
2016 |
Prog Transplant |
pmid:27207408
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Effect of the knockdown of Cabin1 on p53 in glomerular podocyte. |
2016 |
J. Recept. Signal Transduct. Res. |
pmid:26400065
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Perioperative Desensitization Improves Outcomes Among Crossmatch Positive Recipients of Deceased Donor Renal Transplants. |
2016 |
Prog Transplant |
pmid:27207404
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Risk Assessment of Drug-Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients. |
2016 |
Ther Drug Monit |
pmid:27310200
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Menninga NJ et al. |
Restless Legs Syndrome Following Lung Transplantation: Prevalence and Relationship With Tacrolimus Exposure. |
2016 |
Prog Transplant |
pmid:27207403
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Badri PS et al. |
Pharmacokinetics of Tacrolimus and Cyclosporine in Liver Transplant Recipients Receiving 3 Direct-Acting Antivirals as Treatment for Hepatitis C Infection. |
2016 |
Ther Drug Monit |
pmid:27310199
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Nankivell BJ et al. |
Calcineurin Inhibitor Nephrotoxicity Through the Lens of Longitudinal Histology: Comparison of Cyclosporine and Tacrolimus Eras. |
2016 |
Transplantation |
pmid:27306529
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Reeves TM et al. |
Targeting Kv1.3 channels to reduce white matter pathology after traumatic brain injury. |
2016 |
Exp. Neurol. |
pmid:27302680
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RodrÃguez-AusÃn P et al. |
Topical tacrolimus 0.03% for the treatment of ocular psoriasis. |
2016 |
Arch Soc Esp Oftalmol |
pmid:27130870
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Stifft F et al. |
Effect of Breakfast on the Exposure of the Once-Daily Tacrolimus Formulation in Stable Kidney Transplant Recipients. |
2016 |
Ther Drug Monit |
pmid:27128604
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Acne keloidalis nuchae in renal transplant patients receiving tacrolimus and sirolimus. |
2016 |
Australas. J. Dermatol. |
pmid:27124649
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Influence of Absorption, Distribution, Metabolism, and Excretion Genomic Variants on Tacrolimus/Sirolimus Blood Levels and Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation. |
2016 |
Biol. Blood Marrow Transplant. |
pmid:26325438
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Matsukawa T et al. |
Reduced-dose methotrexate in combination with tacrolimus was associated with rapid engraftment and recovery from oral mucositis without affecting the incidence of GVHD. |
2016 |
Int. J. Hematol. |
pmid:27119977
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Comparison of different therapies in high-risk patients with idiopathic membranous nephropathy. |
2016 |
J. Formos. Med. Assoc. |
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[Removal of senescent cells: towards a better future?] |
2016 |
Med Sci (Paris) |
pmid:28008848
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Beta Cell Function and Insulin Resistance After Conversion from Tacrolimus Twice-Daily to Extended-Release Tacrolimus Once-Daily in Stable Renal Transplant Recipients. |
2016 |
Ann. Transplant. |
pmid:27980321
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Castagna L et al. |
Tacrolimus compared with cyclosporine A after haploidentical T-cell replete transplantation with post-infusion cyclophosphamide. |
2016 |
Bone Marrow Transplant. |
pmid:26595078
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Wang YY et al. |
Characterization of Discrete Phosphopantetheinyl Transferases in Streptomyces tsukubaensis L19 Unveils a Complicate Phosphopantetheinylation Network. |
2016 |
Sci Rep |
pmid:27052100
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Lee DR et al. |
Enhanced dissolution and oral absorption of tacrolimus by supersaturable self-emulsifying drug delivery system. |
2016 |
Int J Nanomedicine |
pmid:27051286
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Cai SC et al. |
Topical calcineurin inhibitors in eczema and cancer association: A cohort study. |
2016 |
J Dermatolog Treat |
pmid:27049893
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Aldoss I et al. |
Cytogenetics Does Not Impact Outcomes in Adult Patients with Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation. |
2016 |
Biol. Blood Marrow Transplant. |
pmid:27044907
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Yamamoto T et al. |
Editorial: tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis--authors' reply. |
2016 |
Aliment. Pharmacol. Ther. |
pmid:27040167
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Taylor KM and Sparrow MP |
Editorial: tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis. |
2016 |
Aliment. Pharmacol. Ther. |
pmid:27040166
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Imamura CK et al. |
Impact of cytochrome P450 2C19 polymorphisms on the pharmacokinetics of tacrolimus when coadministered with voriconazole. |
2016 |
J Clin Pharmacol |
pmid:26239045
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Dosing of Enteric-Coated Mycophenolate Sodium Under Routine Conditions: An Observational, Multicenter Study in Kidney Transplantation. |
2016 |
Ann. Transplant. |
pmid:27122116
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Triptolide Reduces the Required Dose of Tacrolimus by Attenuating Inflammation, Enhancing Immunosuppression, and Increasing Donor Chimerism in a Heterotopic Hindlimb Transplantation Model. |
2016 |
Plast. Reconstr. Surg. |
pmid:27879593
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Lee WS et al. |
Efficacy and safety of low-dose tacrolimus for active rheumatoid arthritis with an inadequate response to methotrexate. |
2016 |
Korean J. Intern. Med. |
pmid:26961485
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