tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Migraine with Aura D020325 1 associated lipids
Porokeratosis D017499 1 associated lipids
Lentigo D007911 1 associated lipids
Mutism D009155 1 associated lipids
Amyloid Neuropathies D017772 1 associated lipids
Cervical Intraepithelial Neoplasia D018290 1 associated lipids
Flaviviridae Infections D018178 1 associated lipids
Idiopathic Interstitial Pneumonias D054988 1 associated lipids
Dysuria D053159 1 associated lipids
Denys-Drash Syndrome D030321 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Suda D et al. The effect of bone mass and architecture on mandibular condyle after mandibular distraction. 2017 Oral Surg Oral Med Oral Pathol Oral Radiol pmid:28864292
Garg V et al. Proglycosomes: A novel nano-vesicle for ocular delivery of tacrolimus. 2017 Colloids Surf B Biointerfaces pmid:28575739
Ng YZ et al. Fluorescence Polarization Assay for Small Molecule Screening of FK506 Biosynthesized in 96-Well Microtiter Plates. 2017 Biochemistry pmid:28841306
Jogiraju VK et al. Application of physiologically based pharmacokinetic modeling to predict drug disposition in pregnant populations. 2017 Biopharm Drug Dispos pmid:28474821
Trasi NS et al. Non-Sink Dissolution Behavior and Solubility Limit of Commercial Tacrolimus Amorphous Formulations. 2017 J Pharm Sci pmid:27816263
David-Neto E et al. Longitudinal Pharmacokinetics of Everolimus When Combined With Low-level of Tacrolimus in Elderly Renal Transplant Recipients. 2017 Transplantation pmid:27798513
Caraveo G et al. FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:29229832
Wang Y et al. Calcineurin Antagonizes AMPK to Regulate Lipolysis in Caenorhabditis elegans. 2017 Molecules pmid:28672869
Li X et al. Tacrolimus induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-429 and its target of RhoE. 2017 Biochem. Biophys. Res. Commun. pmid:28669722
Yuan D et al. Effect of Vitamin D and Tacrolimus Combination Therapy on IgA Nephropathy. 2017 Med. Sci. Monit. pmid:28659572
Devaux S et al. RhoA Inhibitor Treatment At Acute Phase of Spinal Cord Injury May Induce Neurite Outgrowth and Synaptogenesis. 2017 Mol. Cell Proteomics pmid:28659490
Qazi Y et al. Efficacy and Safety of Everolimus Plus Low-Dose Tacrolimus Versus Mycophenolate Mofetil Plus Standard-Dose Tacrolimus in De Novo Renal Transplant Recipients: 12-Month Data. 2017 Am. J. Transplant. pmid:27775865
Liu C et al. Tacrolimus Improves Symptoms of Children With Myasthenia Gravis Refractory to Prednisone. 2017 Pediatr. Neurol. pmid:29074055
Park SS et al. Beneficial Role of Low-Dose Antithymocyte Globulin in Unrelated Stem Cell Transplantation for Adult Patients with Acquired Severe Aplastic Anemia: Reduction of Graft-versus-Host Disease and Improvement of Graft-versus-Host Disease-Free, Failure-Free Survival Rate. 2017 Biol. Blood Marrow Transplant. pmid:28554856
Chen YS et al. Population pharmacokinetic analysis of tacrolimus in Chinese myasthenia gravis patients. 2017 Acta Pharmacol. Sin. pmid:28552913
Kim HS et al. The Protective Effect of Febuxostat on Chronic Tacrolimus-Induced Nephrotoxicity in Rats. 2017 Nephron pmid:27701176
Pinsk V et al. Complete Reversion of Familial Adenomatous Polyposis Phenotype Associated with Tacrolimus and Mycophenolate Mofetil Treatment Following Kidney Transplantation. 2017 Anticancer Res. pmid:28551651
Li Y et al. [Study on the Effect of Immunosuppressive Agent FK506 on Growth and Migration of Lung Cancer Cell]. 2017 Zhongguo Fei Ai Za Zhi pmid:28738959
Vanhove T et al. Fexofenadine, a Putative In Vivo P-glycoprotein Probe, Fails to Predict Clearance of the Substrate Tacrolimus in Renal Recipients. 2017 Clin. Pharmacol. Ther. pmid:28437851
Alvarez-Elías AC et al. A Retrospective Study on Mycophenolic Acid Drug Interactions: Effect of Prednisone, Sirolimus, and Tacrolimus With MPA. 2017 Ther Drug Monit pmid:28437284
Alhamad T et al. Targeting High Calcineurin Inhibitor Levels After Acute Rejection With Less Tremor: A New Strategy. 2017 Transplantation pmid:28422926
Heemann U and Viklicky O Is trough level variability the new tool for identifying patients at risk for rejection after transplantation? 2017 Nephrol. Dial. Transplant. pmid:28186537
Gardenier JC et al. Topical tacrolimus for the treatment of secondary lymphedema. 2017 Nat Commun pmid:28186091
Peng T et al. Protective effects of tacrolimus on podocytes in early diabetic nephropathy in rats. 2017 Mol Med Rep pmid:28339051
Huang TQ et al. Protection of FK506 against neuronal apoptosis and axonal injury following experimental diffuse axonal injury. 2017 Mol Med Rep pmid:28339015
Saeki H Management of Atopic Dermatitis in Japan. 2017 J Nippon Med Sch pmid:28331140
Truffinet O et al. Tacrolimus Exerts Only a Transient Effectiveness in Refractory Pediatric Crohn Disease: A Case Series. 2017 J. Pediatr. Gastroenterol. Nutr. pmid:27429426
Spallanzani V et al. Red blood cell exchange as an approach for treating a case of severe tacrolimus overexposure. 2017 Transfus. Apher. Sci. pmid:28223040
Kasahara M et al. Living donor liver transplantation during the first 3 months of life. 2017 Liver Transpl. pmid:28220684
Chen WY et al. Betel Nut Chewing Is Associated With Reduced Tacrolimus Concentration in Taiwanese Liver Transplant Recipients. 2017 Transplant. Proc. pmid:28219593
Regunath H et al. Early diagnosis of Ehrlichia ewingii infection in a lung transplant recipient by peripheral blood smear. 2017 Transpl Infect Dis pmid:28036138
Shoughy SS and Tabbara KF Topical tacrolimus solution in autoimmune polyglandular syndrome-1-associated keratitis. 2017 Br J Ophthalmol pmid:28137823
Onodera M et al. ATP-binding cassette subfamily B member 1 1236C/T polymorphism significantly affects the therapeutic outcome of tacrolimus in patients with refractory ulcerative colitis. 2017 J. Gastroenterol. Hepatol. pmid:28135009
Kirpalani A et al. Idiosyncratic drug reactions and membranous glomerulopathy. 2017 BMJ Case Rep pmid:28137906
Classen J et al. Seasonal leukotrichia in a German shepherd dog. A case report. 2017 Tierarztl Prax Ausg K Kleintiere Heimtiere pmid:28094416
Kim JM et al. Differences in Peripheral Blood Lymphocytes between Brand-Name and Generic Tacrolimus Used in Stable Liver Transplant Recipients. 2017 Med Princ Pract pmid:28092916
Viklicky O et al. Sequential Targeting of CD52 and TNF Allows Early Minimization Therapy in Kidney Transplantation: From a Biomarker to Targeting in a Proof-Of-Concept Trial. 2017 PLoS ONE pmid:28085915
Naniwa T et al. Efficacy of add-on tacrolimus on methotrexate to maintain clinical remission after rediscontinuation of a tumor necrosis factor inhibitor in rheumatoid arthritis patients who relapsed shortly after discontinuation of the same tumor necrosis factor inhibitor due to clinical remission. 2017 Mod Rheumatol pmid:27143107
Pimentel AL et al. Diagnostic accuracy of glycated hemoglobin for post-transplantation diabetes mellitus after kidney transplantation: systematic review and meta-analysis. 2017 Nephrol. Dial. Transplant. pmid:28088775
Yang D et al. JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature. 2017 Transpl Infect Dis pmid:28036142
Xu D et al. Tacrolimus improves proteinuria remission in adults with cyclosporine A-resistant or -dependent minimal change disease. 2017 Nephrology (Carlton) pmid:28035723
Igata S et al. Acute right heart failure caused by tacrolimus after renal transplantation: Serial observation by speckle tracking and Doppler echocardiography. 2017 Echocardiography pmid:29178293
Sathyasaikumar KV et al. Xanthurenic Acid Formation from 3-Hydroxykynurenine in the Mammalian Brain: Neurochemical Characterization and Physiological Effects. 2017 Neuroscience pmid:29031603
Li J et al. Wuzhi Tablet ( Extract) is a Promising Tacrolimus-Sparing Agent for Renal Transplant Recipients Who are CYP3A5 Expressers: a Two-Phase Prospective Study. 2017 Drug Metab. Dispos. pmid:28864749
Van Laecke S et al. Effect of Magnesium Supplements on Insulin Secretion After Kidney Transplantation: A Randomized Controlled Trial. 2017 Ann. Transplant. pmid:28848225
Cohen L et al. A novel presentation of Mycobacterium avium complex in a recipient of a lung transplant: a case report. 2017 J Med Case Rep pmid:28844207
Dang W et al. Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication. 2017 Antimicrob. Agents Chemother. pmid:28807916
Nazeer A et al. Factors leading to dyspepsia in renal transplant recipients. 2017 Pan Afr Med J pmid:29515738
Tamura M et al. [A case of anti-PL-7 antibody positive polymyositis with thrombotic microangiopathy]. 2017 Nihon Rinsho Meneki Gakkai Kaishi pmid:29367529
Dardis G et al. Cx43 suppresses evx1 expression to regulate joint initiation in the regenerating fin. 2017 Dev. Dyn. pmid:28577298