Cryan J et al. |
FKBP, the binding protein for the immunosuppressive drug, FK-506, is not an inhibitor of protein kinase C activity. |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:1719972
|
Ryu S and Yasunami Y |
Prevention of immune rejection in rat islet allografts by continuous SC administration of FK 506 using a mini-osmotic pump. |
1991 |
Transplant. Proc. |
pmid:1703710
|
Karlsson H et al. |
The immunosuppressive agent FK506 inhibits in vitro expression of membrane-bound and soluble interleukin-2 receptors on resting but not on activated human lymphocytes. |
1991 |
Immunol. Lett. |
pmid:1720417
|
Alejandro R et al. |
Combined liver-islet allotransplantation in man under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703712
|
|
FK-506 shows similar graft survival rate to cyclosporine but fewer side effects: Pitt transplant team. |
1991 |
Nephrol News Issues |
pmid:1720511
|
Ito T et al. |
The mechanism of tolerance induced by a perioperative injection of bone marrow cells and a brief course of FK 506. |
1991 |
Transplant. Proc. |
pmid:1703716
|
|
The discovery of FK-506 and U.S. development. |
1991 |
Nephrol News Issues |
pmid:1720512
|
Zheng B et al. |
Effects of the new and highly active immunosuppressant, rapamycin, on lymphoid tissues and cells in vivo. |
1991 |
Transplant. Proc. |
pmid:1703717
|
Mieles L et al. |
Interaction between FK506 and clotrimazole in a liver transplant recipient. |
1991 |
Transplantation |
pmid:1721250
|
Yabuuchi H et al. |
Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin. |
1991 |
Transplant. Proc. |
pmid:1703718
|
|
First International Congress on FK 506. August 21-24, 1991, Pittsburgh, PA. |
1991 |
Transplant. Proc. |
pmid:1721253
|
Goto T et al. |
FK 506: historical perspectives. |
1991 |
Transplant. Proc. |
pmid:1721254
|
Pichard L et al. |
Effect of FK 506 on human hepatic cytochromes P-450: interaction with CyA. |
1991 |
Transplant. Proc. |
pmid:1721279
|
Christians U et al. |
Interactions of FK 506 and cyclosporine metabolism. |
1991 |
Transplant. Proc. |
pmid:1721280
|
Wu YM et al. |
Interaction between FK 506 and cyclosporine in dogs. |
1991 |
Transplant. Proc. |
pmid:1721281
|
Habucky K et al. |
The pharmacodynamics of pentobarbital following FK 506 therapy. |
1991 |
Transplant. Proc. |
pmid:1721282
|
Farghali H et al. |
Effect of FK 506 chronic administration on bromosulphthalein hepatic excretion in rats. |
1991 |
Transplant. Proc. |
pmid:1721283
|
Farghali H et al. |
A biochemical and 31P-NMR investigation of the effect of FK 506 and cyclosporine pretreatment on immobilized hepatocytes perifused with ethanol. |
1991 |
Transplant. Proc. |
pmid:1721284
|
Farghali H et al. |
FK 506 modulates D-galactosamine-induced hepatitis in rats. |
1991 |
Transplant. Proc. |
pmid:1721285
|
Müller MK et al. |
Inhibition of insulin release by FK 506 and its prevention by rioprostil, a stable prostaglandin E1 analogue. |
1991 |
Transplant. Proc. |
pmid:1721286
|
Wang SC et al. |
FK 506, rapamycin, and cyclosporine: effects on IL-4 and IL-10 mRNA levels in a T-helper 2 cell line. |
1991 |
Transplant. Proc. |
pmid:1721312
|
Woo J et al. |
Kinetics of early T-cell repopulation in the mouse following syngeneic bone marrow transplantation: FK 506 causes a maturational defect of CD4+ CD8- T cells. |
1991 |
Transplant. Proc. |
pmid:1721313
|
McCarthy SA et al. |
Effects of FK 506 and cyclosporine on T-cell tolerance: inhibition of a "protective" mechanism that regulates activation-induced apoptosis in developing thymocytes. |
1991 |
Transplant. Proc. |
pmid:1721314
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive activities of mycophenolic acid, bredinin, FK 506, cyclosporine, and rapamycin. |
1991 |
Transplant. Proc. |
pmid:1721315
|
Matsuura T et al. |
Beneficial immunosuppressive effect of combined use of FK 506 and cyclosporine assessed by proliferative responses of cloned human T cells. |
1991 |
Transplant. Proc. |
pmid:1721316
|
Jiang H et al. |
Combined immunosuppressive effect of FK 506 and other immunosuppressive agents on PHA- and CD3-stimulated human lymphocyte proliferation in vitro. |
1991 |
Transplant. Proc. |
pmid:1721317
|
Yagihashi A et al. |
The effect of FK 506 on peripheral blood T-lymphocyte subsets in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721318
|
Mieles LA et al. |
Liver transplantation of American veterans under FK 506 immunosuppression: a preliminary report. |
1991 |
Transplant. Proc. |
pmid:1721344
|
Nakazato P et al. |
Early experience with FK 506 induction immunosuppression--suggestion for using oral FK 506. |
1991 |
Transplant. Proc. |
pmid:1721345
|
Nakamura K et al. |
The lymphocytotoxic crossmatch in liver transplantation: a clinicopathologic analysis. |
1991 |
Transplant. Proc. |
pmid:1721346
|
Jain AB et al. |
Correlation of rejection episodes with FK 506 dosage, FK 506 level, and steroids following primary orthotopic liver transplant. |
1991 |
Transplant. Proc. |
pmid:1721347
|
Takaya S et al. |
Retransplantation of liver: a comparison of FK 506- and cyclosporine-treated patients. |
1991 |
Transplant. Proc. |
pmid:1721348
|
Morel P et al. |
Liver retransplantation in adults: overall results and determinant factors affecting the outcome. |
1991 |
Transplant. Proc. |
pmid:1721349
|
Felser I et al. |
Changes in quality of life following conversion from CyA to FK 506 in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721350
|
Carroll PB et al. |
Effect of the immunosuppressant FK506 on glucose-induced insulin secretion from adult rat islets of Langerhans. |
1991 |
Transplantation |
pmid:1702911
|
Starzl TE et al. |
Hepatotrophic effects of FK506 in dogs. |
1991 |
Transplantation |
pmid:1702912
|
Keicho N et al. |
Effects of an immunosuppressant, FK506, on interleukin 1 alpha production by human macrophages and a macrophage-like cell line, U937. |
1991 |
Cell. Immunol. |
pmid:1703047
|
White DJ |
FK506: the promise and the paradox. |
1991 |
Clin. Exp. Immunol. |
pmid:1703053
|
Frayha HH et al. |
Lymphoproliferative disorder in a liver transplant patient on FK 506. |
1991 |
Lancet |
pmid:1703258
|
Burman K and Crawford DH |
Effect of FK 506 on Epstein-Barr virus specific cytotoxic T cells. |
1991 |
Lancet |
pmid:1703259
|
Nalesnik MA et al. |
Lymphoproliferative disorders arising under immunosuppression with FK 506: initial observations in a large transplant population. |
1991 |
Transplant. Proc. |
pmid:1703335
|
Morris SM et al. |
Disruption of renal function and gene expression by FK 506 and cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721375
|
Lieberman KV et al. |
FK 506 is a direct glomeruloconstrictor, as determined by electrical resistance pulse sizing (ERPS). |
1991 |
Transplant. Proc. |
pmid:1721376
|
Ueda D et al. |
Influence of FK 506 on renal blood flow. |
1991 |
Transplant. Proc. |
pmid:1721377
|
Perico N et al. |
FK 506 does not affect the glomerular filtration rate and renal plasma flow in the rat. |
1991 |
Transplant. Proc. |
pmid:1721378
|
Wagner K et al. |
Effect of FK 506 on excretion of urinary enzymes in rats. |
1991 |
Transplant. Proc. |
pmid:1721379
|
Prasad SJ et al. |
In vitro effects of cyclosporine and FK 506 on the renal cortex. |
1991 |
Transplant. Proc. |
pmid:1721380
|
Yamada K et al. |
Short-term FK 506-induced morphological changes in rat kidneys. |
1991 |
Transplant. Proc. |
pmid:1721381
|
Moutabarrik A et al. |
FK 506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells and tubular cell toxicity in vitro. |
1991 |
Transplant. Proc. |
pmid:1721382
|
Moutabarrik A et al. |
In vitro FK 506 kidney tubular cell toxicity. |
1991 |
Transplant. Proc. |
pmid:1721383
|
Shinozuka H et al. |
Effect of FK 506 on experimental liver carcinogenesis. |
1991 |
Transplant. Proc. |
pmid:1721407
|
Pelekanou V et al. |
FK 506 and rapamycin do not affect platelet aggregation or mitochondrial function. |
1991 |
Transplant. Proc. |
pmid:1721408
|
Tai J et al. |
In vivo and in vitro effect of FK 506 on rat Leydig cell function. |
1991 |
Transplant. Proc. |
pmid:1721409
|
Ricordi C et al. |
Human islet allotransplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721410
|
Tze WJ et al. |
Long-term survival of islet allografts in diabetic rats treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721411
|
Wang X et al. |
Intraportal FK 506 improves intrahepatic islet allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721412
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721413
|
Steinmann B et al. |
Mechanism of action of FK 506 and cyclosporin. |
1991 |
Lancet |
pmid:1704088
|
Sewing KF and Christians U |
FK 506. |
1991 |
Lancet |
pmid:1704090
|
Wiederrecht G et al. |
FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1704127
|
Ziccardi VB et al. |
Maxillofacial considerations in orthotopic liver transplantation. |
1991 |
Oral Surg. Oral Med. Oral Pathol. |
pmid:1704494
|
Bierer BE et al. |
The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation. |
1991 |
Eur. J. Immunol. |
pmid:1705513
|
Heitman J et al. |
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1705713
|
Goebl MG |
The peptidyl-prolyl isomerase, FK506-binding protein, is most likely the 12 kd endogenous inhibitor 2 of protein kinase C. |
1991 |
Cell |
pmid:1706222
|
de Paulis A et al. |
FK-506, a potent novel inhibitor of the release of proinflammatory mediators from human Fc epsilon RI+ cells. |
1991 |
J. Immunol. |
pmid:1706398
|
DeValeria PA et al. |
FK 506 fails to reverse moderate cardiac allograft rejection in a canine heterotopic model. |
1991 |
Transplant. Proc. |
pmid:1721438
|
Jiang H et al. |
Prolonged cardiac allograft survival in sensitized rats by low-dose FK 506 in combination with splenectomy. |
1991 |
Transplant. Proc. |
pmid:1721439
|
Sato K et al. |
Comparative study of FK 506, cyclosporine, and triple regimen immunosuppression with FK 506, cyclosporine, and mizoribine. |
1991 |
Transplant. Proc. |
pmid:1721440
|
Katayama Y et al. |
Immunosuppressive effects of FK 506 in rat lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721441
|
Yokomise H et al. |
Immunosuppressive effects of FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721442
|
Hasegawa S et al. |
FK 506 and cyclosporine: effects and side effects in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721443
|
Wada H et al. |
Dose response to FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721444
|
Lin CY et al. |
Effects of FK 506 on the biochemical markers in canine lung allograft rejection. |
1991 |
Transplant. Proc. |
pmid:1721445
|
Palaszynski EW et al. |
Purification and characterization of cyclosporine and FK-506 binding proteins from a human T-helper cell line. |
1991 |
Clin. Biochem. |
pmid:1711940
|
Shiraki K et al. |
Effect of FK-506 on replication of human cytomegalovirus in vitro. |
1991 |
J. Antibiot. |
pmid:1712008
|
Sigal NH et al. |
Inhibition of human T-cell activation by FK 506, rapamycin, and cyclosporine A. |
1991 |
Transplant. Proc. |
pmid:1712132
|
Fung JJ et al. |
Current status of FK 506 in liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1712133
|
Francavilla A et al. |
Studies on mechanisms of augmentation of liver regeneration by cyclosporine and FK 506. |
1991 |
Hepatology |
pmid:1712337
|
Aoki H |
[FK 506, a new immunosuppressant produced by a Streptomyces]. |
1991 |
Nippon Rinsho |
pmid:1712403
|
Hultsch T et al. |
Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1712484
|
Granelli-Piperno A and McHugh P |
Characterization of a protein that regulates the DNA-binding activity of NF-AT, the nuclear factor of activated T cells. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1722332
|
Nelson PA et al. |
cDNA encoding murine FK506-binding protein (FKBP): nucleotide and deduced amino acid sequence. |
1991 |
Gene |
pmid:1722474
|
Chen MF et al. |
The influence of FK-506 on the thymus and spleen in normal C3H/He mice: flow cytometric analysis of lymphocyte subpopulations. |
1991 |
Immunol. Lett. |
pmid:1722778
|
Sakai K et al. |
The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents. |
1991 |
Brain Res. |
pmid:1723023
|
Weaver JL et al. |
Comparison of the in vitro and biophysical effects of cyclosporine A, FK-506, and mycophenolic acid on human peripheral blood lymphocytes. |
1991 |
Immunopharmacol Immunotoxicol |
pmid:1723084
|
Burres NS et al. |
Dunaimycins, a new complex of spiroketal 24-membered macrolides with immunosuppressive activity. III. Immunosuppressive activities of dunaimycins. |
1991 |
J. Antibiot. |
pmid:1723403
|
Nielsen JB et al. |
Biosynthesis of the immunosuppressant immunomycin: the enzymology of pipecolate incorporation. |
1991 |
Biochemistry |
pmid:2043618
|
|
FK 506--an investigational immunosuppressant. |
1991 |
Med Lett Drugs Ther |
pmid:1716722
|
Ricordi C et al. |
In vivo effect of FK506 on human pancreatic islets. |
1991 |
Transplantation |
pmid:1716797
|
Katz IA et al. |
Comparison of the effects of FK506 and cyclosporine on bone mineral metabolism in the rat. A pilot study. |
1991 |
Transplantation |
pmid:1716801
|
Morris RE |
Rapamycin: FK506's fraternal twin or distant cousin? |
1991 |
Immunol. Today |
pmid:1715165
|
Pezze JL and Whiteman K |
Transplantation's newest weapon FK 506. |
1991 |
Am J Nurs |
pmid:1716857
|
Baumann G et al. |
Cyclosporin A and FK-506 both affect DNA binding of regulatory nuclear proteins to the human interleukin-2 promoter. |
1991 |
New Biol. |
pmid:1715185
|
Marquis-Omer D et al. |
Stabilization of the FK506 binding protein by ligand binding. |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:1716886
|
Liu J et al. |
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. |
1991 |
Cell |
pmid:1715244
|
Sakai K et al. |
[The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents--comparison with cyclosporin A]. |
1991 |
No To Shinkei |
pmid:1716937
|
Henderson DJ et al. |
Comparison of the effects of FK-506, cyclosporin A and rapamycin on IL-2 production. |
1991 |
Immunology |
pmid:1715317
|
DeFranco AL |
Signal transduction. Immunosuppressants at work. |
1991 |
Nature |
pmid:1715515
|
Flanagan WM et al. |
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. |
1991 |
Nature |
pmid:1715516
|
McWhinnie DL and Morris PJ |
Combination drug therapies for immunosuppression in transplantation. |
1991 |
Ann. Acad. Med. Singap. |
pmid:1724724
|