Fauconnier J et al. |
Frequency-dependent and proarrhythmogenic effects of FK-506 in rat ventricular cells. |
2005 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:15471978
|
König S et al. |
Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle. |
2013 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:24056904
|
Kraiss LW et al. |
Fluid flow activates a regulator of translation, p70/p85 S6 kinase, in human endothelial cells. |
2000 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:10775131
|
Kohno M et al. |
A new cardioprotective agent, JTV519, improves defective channel gating of ryanodine receptor in heart failure. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12433661
|
Gómez AM et al. |
FKBP12.6 overexpression decreases Ca2+ spark amplitude but enhances [Ca2+]i transient in rat cardiac myocytes. |
2004 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:15271664
|
Sasamori K et al. |
Cyclic ADP-ribose, a putative Ca2+-mobilizing second messenger, operates in submucosal gland acinar cells. |
2004 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:14990397
|
Lum H et al. |
Protein phosphatase 2B inhibitor potentiates endothelial PKC activity and barrier dysfunction. |
2001 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:11504680
|
Yaghi A and Sims SM |
Constrictor-induced translocation of NFAT3 in human and rat pulmonary artery smooth muscle. |
2005 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:16055480
|
Bouvier N et al. |
Cyclosporine triggers endoplasmic reticulum stress in endothelial cells: a role for endothelial phenotypic changes and death. |
2009 |
Am. J. Physiol. Renal Physiol. |
pmid:18987109
|
Ren H et al. |
Phosphatase inhibition increases AQP2 accumulation in the rat IMCD apical plasma membrane. |
2016 |
Am. J. Physiol. Renal Physiol. |
pmid:27488997
|
Thai TL et al. |
ADP-ribosyl cyclase and ryanodine receptor activity contribute to basal renal vasomotor tone and agonist-induced renal vasoconstriction in vivo. |
2007 |
Am. J. Physiol. Renal Physiol. |
pmid:17652368
|
Peherstorfer E et al. |
Effects of microinjection of synthetic Bcl-2 domain peptides on apoptosis of renal tubular epithelial cells. |
2002 |
Am. J. Physiol. Renal Physiol. |
pmid:12060601
|
Axelsson J et al. |
Scavengers of reactive oxygen species, paracalcitol, RhoA, and Rac-1 inhibitors and tacrolimus inhibit angiotensin II-induced actions on glomerular permeability. |
2013 |
Am. J. Physiol. Renal Physiol. |
pmid:23657856
|
Mohebbi N et al. |
The calcineurin inhibitor FK506 (tacrolimus) is associated with transient metabolic acidosis and altered expression of renal acid-base transport proteins. |
2009 |
Am. J. Physiol. Renal Physiol. |
pmid:19439519
|
Cho SG et al. |
Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis. |
2010 |
Am. J. Physiol. Renal Physiol. |
pmid:20410216
|
De Miguel C et al. |
Infiltrating T lymphocytes in the kidney increase oxidative stress and participate in the development of hypertension and renal disease. |
2011 |
Am. J. Physiol. Renal Physiol. |
pmid:21159736
|
Rojas-Vega L et al. |
Increased phosphorylation of the renal Na+-Cl- cotransporter in male kidney transplant recipient patients with hypertension: a prospective cohort. |
2015 |
Am. J. Physiol. Renal Physiol. |
pmid:26336164
|
Edinger RS et al. |
Effect of immunosuppressive agents on glucocorticoid receptor function in A6 cells. |
2002 |
Am. J. Physiol. Renal Physiol. |
pmid:12110508
|
Ilori TO et al. |
Acute calcineurin inhibition with tacrolimus increases phosphorylated UT-A1. |
2012 |
Am. J. Physiol. Renal Physiol. |
pmid:22205230
|
Amberg GC et al. |
Regulation of A-type potassium channels in murine colonic myocytes by phosphatase activity. |
2001 |
Am. J. Physiol., Cell Physiol. |
pmid:11698261
|
Ahn HS et al. |
Calcineurin-independent inhibition of KV1.3 by FK-506 (tacrolimus): a novel pharmacological property. |
2007 |
Am. J. Physiol., Cell Physiol. |
pmid:17166943
|
Wang YX et al. |
FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells. |
2004 |
Am. J. Physiol., Cell Physiol. |
pmid:14592808
|
Sans MD and Williams JA |
Calcineurin is required for translational control of protein synthesis in rat pancreatic acini. |
2004 |
Am. J. Physiol., Cell Physiol. |
pmid:15044154
|
Bayguinov O et al. |
Muscarinic stimulation increases basal Ca(2+) and inhibits spontaneous Ca(2+) transients in murine colonic myocytes. |
2001 |
Am. J. Physiol., Cell Physiol. |
pmid:11171588
|
Angus LM et al. |
Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1{alpha}, drives utrophin gene expression at the neuromuscular junction. |
2005 |
Am. J. Physiol., Cell Physiol. |
pmid:15930144
|
Zhang Y et al. |
K restriction inhibits protein phosphatase 2B (PP2B) and suppression of PP2B decreases ROMK channel activity in the CCD. |
2008 |
Am. J. Physiol., Cell Physiol. |
pmid:18184875
|
Yue G et al. |
The effect of rapamycin on single ENaC channel activity and phosphorylation in A6 cells. |
2000 |
Am. J. Physiol., Cell Physiol. |
pmid:10898719
|
Nam JH et al. |
Expression of TASK-2 and its upregulation by B cell receptor stimulation in WEHI-231 mouse immature B cells. |
2011 |
Am. J. Physiol., Cell Physiol. |
pmid:21307343
|
Nakagawa K et al. |
Immunosuppression with tacrolimus improved reproductive outcome of women with repeated implantation failure and elevated peripheral blood TH1/TH2 cell ratios. |
2015 |
Am. J. Reprod. Immunol. |
pmid:25394810
|
Nakagawa K et al. |
Immunosuppressive treatment using tacrolimus promotes pregnancy outcome in infertile women with repeated implantation failures. |
2017 |
Am. J. Reprod. Immunol. |
pmid:28466977
|
Saito S et al. |
Role of Paternal Antigen-Specific Treg Cells in Successful Implantation. |
2016 |
Am. J. Reprod. Immunol. |
pmid:26706630
|
Kofod L et al. |
Endometrial immune markers are potential predictors of normal fertility and pregnancy after in vitro fertilization. |
2017 |
Am. J. Reprod. Immunol. |
pmid:28440588
|
Tabata C et al. |
Calcineurin/NFAT pathway: a novel regulator of parturition. |
2009 |
Am. J. Reprod. Immunol. |
pmid:19527231
|
Goldthorpe H et al. |
Occlusive lung arterial lesions in endothelial-targeted, fas-induced apoptosis transgenic mice. |
2015 |
Am. J. Respir. Cell Mol. Biol. |
pmid:25879383
|
Fujiki M et al. |
Role of T cells in bronchoalveolar space in the development of interstitial pneumonia induced by superantigen in autoimmune-prone mice. |
1999 |
Am. J. Respir. Cell Mol. Biol. |
pmid:10572064
|
Deuse T et al. |
Mechanisms behind local immunosuppression using inhaled tacrolimus in preclinical models of lung transplantation. |
2010 |
Am. J. Respir. Cell Mol. Biol. |
pmid:19880819
|
Rolfe FG et al. |
Cyclosporin A and FK506 reduce interleukin-5 mRNA abundance by inhibiting gene transcription. |
1997 |
Am. J. Respir. Cell Mol. Biol. |
pmid:9271313
|
Yerkovich ST et al. |
Survival after bronchiolitis obliterans syndrome. |
2011 |
Am. J. Respir. Crit. Care Med. |
pmid:21325085
|
Bhorade S et al. |
Comparison of sirolimus with azathioprine in a tacrolimus-based immunosuppressive regimen in lung transplantation. |
2011 |
Am. J. Respir. Crit. Care Med. |
pmid:20833822
|
Koshika T et al. |
Pretreatment with FK506 improves survival rate and gas exchange in canine model of acute lung injury. |
2001 |
Am. J. Respir. Crit. Care Med. |
pmid:11208629
|
Saeki K et al. |
Endobronchial Lesions of Mycobacterium abscessus Infection in an Immunocompromised Patient. |
2017 |
Am. J. Respir. Crit. Care Med. |
pmid:28199133
|
Joshi MS et al. |
Calcineurin regulates myocardial function during acute endotoxemia. |
2006 |
Am. J. Respir. Crit. Care Med. |
pmid:16424445
|
Fauvel H et al. |
Protective effects of cyclosporin A from endotoxin-induced myocardial dysfunction and apoptosis in rats. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11850335
|
Spiekerkoetter E et al. |
Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension. |
2015 |
Am. J. Respir. Crit. Care Med. |
pmid:26177174
|
Raofi V et al. |
A prospective randomized trial comparing the efficacy of tacrolimus versus cyclosporine in black recipients of primary cadaveric renal transplants. |
1999 |
Am. J. Surg. |
pmid:10326847
|
Tanaka K et al. |
Living related liver transplantation in children. |
1994 |
Am. J. Surg. |
pmid:7517649
|
Li X et al. |
Increased iNOS-expressing macrophage in long-term surviving rat small-bowel grafts. |
2007 |
Am. J. Surg. |
pmid:17618815
|
Rabkin JM et al. |
Immunosuppression impact on long-term cardiovascular complications after liver transplantation. |
2002 |
Am. J. Surg. |
pmid:12034401
|
Jurim O et al. |
Living-donor liver transplantation at UCLA. |
1995 |
Am. J. Surg. |
pmid:7538267
|
Lee KK et al. |
Successful treatment of ongoing intestinal allograft rejection permits recovery of graft structure and function. |
1993 |
Am. J. Surg. |
pmid:7678188
|
Finn L et al. |
Epstein-Barr virus infections in children after transplantation of the small intestine. |
1998 |
Am. J. Surg. Pathol. |
pmid:9500771
|
Randhawa PS et al. |
The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine. |
1993 |
Am. J. Surg. Pathol. |
pmid:7680544
|
Minervini MI et al. |
Acute renal allograft rejection with severe tubulitis (Banff 1997 grade IB). |
2000 |
Am. J. Surg. Pathol. |
pmid:10757402
|
Randhawa PS et al. |
Microvascular changes in renal allografts associated with FK506 (Tacrolimus) therapy. |
1996 |
Am. J. Surg. Pathol. |
pmid:8772784
|
Singh K et al. |
Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer. |
2014 |
Am. J. Transplant. |
pmid:25359003
|
Dugast E et al. |
Failure of Calcineurin Inhibitor (Tacrolimus) Weaning Randomized Trial in Long-Term Stable Kidney Transplant Recipients. |
2016 |
Am. J. Transplant. |
pmid:27367750
|
Tang Q |
Pharmacokinetics of therapeutic Tregs. |
2014 |
Am. J. Transplant. |
pmid:25358900
|
Wen X et al. |
Comparison of Utilization and Clinical Outcomes for Belatacept- and Tacrolimus-Based Immunosuppression in Renal Transplant Recipients. |
2016 |
Am. J. Transplant. |
pmid:27137884
|
Sikma MA et al. |
Pharmacokinetics and Toxicity of Tacrolimus Early After Heart and Lung Transplantation. |
2015 |
Am. J. Transplant. |
pmid:26053114
|
Ellis CL and Racusen LC |
Mild rise in creatinine six months post kidney transplant. |
2012 |
Am. J. Transplant. |
pmid:22845913
|
Wang Q et al. |
Biodegradable microsphere-loaded tacrolimus enhanced the effect on mice islet allograft and reduced the adverse effect on insulin secretion. |
2004 |
Am. J. Transplant. |
pmid:15084166
|
Schubert M et al. |
Pharmacokinetics of sirolimus and tacrolimus in pediatric transplant patients. |
2004 |
Am. J. Transplant. |
pmid:15084173
|
ter Meulen CG et al. |
Steroid-withdrawal at 3 days after renal transplantation with anti-IL-2 receptor alpha therapy: a prospective, randomized, multicenter study. |
2004 |
Am. J. Transplant. |
pmid:15084178
|
Borrows R et al. |
Steroid sparing with tacrolimus and mycophenolate mofetil in renal transplantation. |
2004 |
Am. J. Transplant. |
pmid:15476485
|
Hernández-Fisac I et al. |
Tacrolimus-induced diabetes in rats courses with suppressed insulin gene expression in pancreatic islets. |
2007 |
Am. J. Transplant. |
pmid:17725683
|
Frassetto LA and Benet LZ |
Pharmacogenomics and transplantation: where are we? |
2004 |
Am. J. Transplant. |
pmid:15147415
|
MacPhee IA et al. |
The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation. |
2004 |
Am. J. Transplant. |
pmid:15147425
|
Artz MA et al. |
Conversion from cyclosporine to tacrolimus improves quality-of-life indices, renal graft function and cardiovascular risk profile. |
2004 |
Am. J. Transplant. |
pmid:15147428
|
Hirsch HH et al. |
Polyomavirus BK replication in de novo kidney transplant patients receiving tacrolimus or cyclosporine: a prospective, randomized, multicenter study. |
2013 |
Am. J. Transplant. |
pmid:23137180
|
Mujtaba MA et al. |
Conversion from tacrolimus to belatacept to prevent the progression of chronic kidney disease in pancreas transplantation: case report of two patients. |
2014 |
Am. J. Transplant. |
pmid:25179306
|
Shihab FS et al. |
Effect of corticosteroid withdrawal on tacrolimus and mycophenolate mofetil exposure in a randomized multicenter study. |
2013 |
Am. J. Transplant. |
pmid:23167508
|
Wlodarczyk Z et al. |
Pharmacokinetics for once- versus twice-daily tacrolimus formulations in de novo kidney transplantation: a randomized, open-label trial. |
2009 |
Am. J. Transplant. |
pmid:19681813
|
Hesselink DA et al. |
Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2. |
2005 |
Am. J. Transplant. |
pmid:15816878
|
Chisholm-Burns MA et al. |
Immunosuppressant therapy adherence and graft failure among pediatric renal transplant recipients. |
2009 |
Am. J. Transplant. |
pmid:19681814
|
Byrne GW et al. |
Warfarin or low-molecular-weight heparin therapy does not prolong pig-to-primate cardiac xenograft function. |
2005 |
Am. J. Transplant. |
pmid:15816881
|
Lucey MR et al. |
A comparison of tacrolimus and cyclosporine in liver transplantation: effects on renal function and cardiovascular risk status. |
2005 |
Am. J. Transplant. |
pmid:15816894
|
Pillebout E et al. |
Renal histopathological lesions after orthotopic liver transplantation (OLT). |
2005 |
Am. J. Transplant. |
pmid:15816895
|
Tydén G et al. |
ABO incompatible kidney transplantations without splenectomy, using antigen-specific immunoadsorption and rituximab. |
2005 |
Am. J. Transplant. |
pmid:15636623
|
Woodle ES et al. |
A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus. |
2005 |
Am. J. Transplant. |
pmid:15636625
|
Mian AN et al. |
Mycoplasma hominis septic arthritis in a pediatric renal transplant recipient: case report and review of the literature. |
2005 |
Am. J. Transplant. |
pmid:15636628
|
Gregoor PS and Weimar W |
Tacrolimus and pure red-cell aplasia. |
2005 |
Am. J. Transplant. |
pmid:15636632
|
Gao R et al. |
Effects of immunosuppressive drugs on in vitro neogenesis of human islets: mycophenolate mofetil inhibits the proliferation of ductal cells. |
2007 |
Am. J. Transplant. |
pmid:17391142
|
Tremblay S et al. |
A Steady-State Head-to-Head Pharmacokinetic Comparison of All FK-506 (Tacrolimus) Formulations (ASTCOFF): An Open-Label, Prospective, Randomized, Two-Arm, Three-Period Crossover Study. |
2017 |
Am. J. Transplant. |
pmid:27340950
|
Hardinger KL et al. |
BK-virus and the impact of pre-emptive immunosuppression reduction: 5-year results. |
2010 |
Am. J. Transplant. |
pmid:20055811
|
De Simone P et al. |
Everolimus with reduced tacrolimus in liver transplantation. |
2013 |
Am. J. Transplant. |
pmid:23601137
|
Fan DM et al. |
Successful ABO-incompatible living-related intestinal transplantation: a 2-year follow-up. |
2015 |
Am. J. Transplant. |
pmid:25808777
|
Chen G et al. |
A synergistic effect between PG490-88 and tacrolimus prolongs renal allograft survival in monkeys. |
2006 |
Am. J. Transplant. |
pmid:16539628
|
Mazariegos GV et al. |
Dendritic cell subset ratio in tolerant, weaning and non-tolerant liver recipients is not affected by extent of immunosuppression. |
2005 |
Am. J. Transplant. |
pmid:15643991
|
Knechtle SJ et al. |
Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring. |
2009 |
Am. J. Transplant. |
pmid:19344431
|
Bahra M et al. |
MMF and calcineurin taper in recurrent hepatitis C after liver transplantation: impact on histological course. |
2005 |
Am. J. Transplant. |
pmid:15644002
|
Bunnapradist S et al. |
Conversion from twice-daily tacrolimus to once-daily extended release tacrolimus (LCPT): the phase III randomized MELT trial. |
2013 |
Am. J. Transplant. |
pmid:23279614
|
Ceschi A et al. |
Acute calcineurin inhibitor overdose: analysis of cases reported to a national poison center between 1995 and 2011. |
2013 |
Am. J. Transplant. |
pmid:23279718
|
Kaplan B and Kirk AD |
Tacrolimus and sirolimus: when bad things happen to good drugs. |
2006 |
Am. J. Transplant. |
pmid:16827845
|
McAlister VC et al. |
Cyclosporin versus tacrolimus as primary immunosuppressant after liver transplantation: a meta-analysis. |
2006 |
Am. J. Transplant. |
pmid:16827858
|
Vanhove T et al. |
High Intrapatient Variability of Tacrolimus Concentrations Predicts Accelerated Progression of Chronic Histologic Lesions in Renal Recipients. |
2016 |
Am. J. Transplant. |
pmid:27013142
|
Rush D et al. |
Lack of benefit of early protocol biopsies in renal transplant patients receiving TAC and MMF: a randomized study. |
2007 |
Am. J. Transplant. |
pmid:17908280
|
Barbas AS et al. |
Posterior reversible encephalopathy syndrome independently associated with tacrolimus and sirolimus after multivisceral transplantation. |
2013 |
Am. J. Transplant. |
pmid:23331705
|
Gatault P et al. |
Reduction of Extended-Release Tacrolimus Dose in Low-Immunological-Risk Kidney Transplant Recipients Increases Risk of Rejection and Appearance of Donor-Specific Antibodies: A Randomized Study. |
2017 |
Am. J. Transplant. |
pmid:27862923
|
Fujishiro J et al. |
Influence of immunosuppression on alloresponse, inflammation and contractile function of graft after intestinal transplantation. |
2010 |
Am. J. Transplant. |
pmid:20642681
|
Miller LW |
Cardiovascular toxicities of immunosuppressive agents. |
2002 |
Am. J. Transplant. |
pmid:12392286
|