tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Discitis D015299 2 associated lipids
Fox-Fordyce Disease D005588 2 associated lipids
Collagen Diseases D003095 2 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Vestibular Diseases D015837 2 associated lipids
Coccidioidomycosis D003047 2 associated lipids
Ileal Neoplasms D007078 2 associated lipids
Lichen Planus, Oral D017676 2 associated lipids
Lymphomatoid Granulomatosis D008230 2 associated lipids
Paresis D010291 2 associated lipids
Myxedema D009230 2 associated lipids
Intestinal Atresia D007409 3 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Epstein-Barr Virus Infections D020031 3 associated lipids
Cryptogenic Organizing Pneumonia D018549 3 associated lipids
Foot Dermatoses D005533 3 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Hyperkalemia D006947 3 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Hematologic Diseases D006402 3 associated lipids
Immune System Diseases D007154 3 associated lipids
Castleman Disease D005871 3 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Anus Diseases D001004 3 associated lipids
Leprosy, Borderline D015439 3 associated lipids
Kidney Tubular Necrosis, Acute D007683 3 associated lipids
Scleritis D015423 3 associated lipids
Anemia, Refractory D000753 3 associated lipids
Wounds, Stab D014951 3 associated lipids
Digestive System Diseases D004066 3 associated lipids
Pemphigus, Benign Familial D016506 3 associated lipids
Ileus D045823 3 associated lipids
Legionellosis D007876 3 associated lipids
Pityriasis D010915 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Keratosis, Actinic D055623 3 associated lipids
Meningococcal Infections D008589 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Glomerulonephritis, Membranoproliferative D015432 3 associated lipids
Perceptual Disorders D010468 3 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Fetal Hypoxia D005311 3 associated lipids
Lichen Planus D008010 3 associated lipids
Toxocariasis D014120 3 associated lipids
Pyoderma Gangrenosum D017511 3 associated lipids
Polyneuropathies D011115 3 associated lipids
Trichomonas Infections D014245 3 associated lipids
Peptic Ulcer Perforation D010439 3 associated lipids
Impetigo D007169 3 associated lipids
Nervous System Autoimmune Disease, Experimental D020721 3 associated lipids
Epidermolysis Bullosa D004820 3 associated lipids
Paronychia D010304 3 associated lipids
Leukoencephalopathies D056784 3 associated lipids
Gingivitis D005891 3 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Facial Neoplasms D005153 3 associated lipids
Cryptococcosis D003453 3 associated lipids
Hemophilia B D002836 3 associated lipids
Pouchitis D019449 3 associated lipids
Osteochondrodysplasias D010009 3 associated lipids
Adrenal Insufficiency D000309 3 associated lipids
Pemphigus D010392 3 associated lipids
Dysgammaglobulinemia D004406 3 associated lipids
Pterygium D011625 3 associated lipids
Carpal Tunnel Syndrome D002349 3 associated lipids
Arthritis, Reactive D016918 3 associated lipids
Foot Ulcer D016523 4 associated lipids
Neoplasms, Second Primary D016609 4 associated lipids
Eczema D004485 4 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Neuritis D009443 4 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Autonomic Nervous System Diseases D001342 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Reflex Sympathetic Dystrophy D012019 4 associated lipids
Optic Nerve Injuries D020221 4 associated lipids
Headache D006261 4 associated lipids
Pain, Intractable D010148 4 associated lipids
Diabetes Complications D048909 4 associated lipids
Balanitis D001446 4 associated lipids
Endomyocardial Fibrosis D004719 4 associated lipids
Amenorrhea D000568 4 associated lipids
Blepharitis D001762 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Hyperuricemia D033461 4 associated lipids
Anemia, Hemolytic D000743 4 associated lipids
Osteoporosis, Postmenopausal D015663 4 associated lipids
Hallucinations D006212 4 associated lipids
Lymphoma, T-Cell, Cutaneous D016410 4 associated lipids
Meningoencephalitis D008590 4 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Prurigo D011536 4 associated lipids
Gastroenteritis D005759 4 associated lipids
Viremia D014766 4 associated lipids
Hepatitis, Viral, Animal D006524 4 associated lipids
Fractures, Spontaneous D005598 4 associated lipids
Gout D006073 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Tang S and Lai KN Quiz page. Posttransplantation lymphoproliferative disorder (PTLD) involving the brain and the allograft. 2005 Am. J. Kidney Dis. pmid:15806458
Rao PS Nephrotic syndrome in patients with peripheral blood stem cell transplant. 2005 Am. J. Kidney Dis. pmid:15806483
de Mattos AM et al. Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future. 2000 Am. J. Kidney Dis. pmid:10676738
Kooman JP et al. A comparison between office and ambulatory blood pressure measurements in renal transplant patients with chronic transplant nephropathy. 2001 Am. J. Kidney Dis. pmid:11382685
Birdwell KA et al. Decreased antibody response to influenza vaccination in kidney transplant recipients: a prospective cohort study. 2009 Am. J. Kidney Dis. pmid:19185404
Wong TY et al. Parvovirus B19 infection causing red cell aplasia in renal transplantation on tacrolimus. 1999 Am. J. Kidney Dis. pmid:10585325
Rostaing L et al. Novel Once-Daily Extended-Release Tacrolimus Versus Twice-Daily Tacrolimus in De Novo Kidney Transplant Recipients: Two-Year Results of Phase 3, Double-Blind, Randomized Trial. 2016 Am. J. Kidney Dis. pmid:26717860
Tang S et al. Use of tacrolimus in steroid- and cyclophosphamide-resistant minimal change nephrotic syndrome. 2003 Am. J. Kidney Dis. pmid:14582073
Pham PT et al. Cyclosporine and tacrolimus-associated thrombotic microangiopathy. 2000 Am. J. Kidney Dis. pmid:11007689
Revelo MP et al. A 14-year-old boy with kidney allograft failure in the first month after transplantation. 2000 Am. J. Kidney Dis. pmid:11007695
Lien YH and Bracamonte ER Quiz page February 2011: acute kidney injury, graft pain, and subtherapeutic levels of tacrolimus. 2011 Am. J. Kidney Dis. pmid:21251536
Pavan M et al. Altered bioavailability of tacrolimus following intravenous administration of tigecycline. 2011 Am. J. Kidney Dis. pmid:21251548
Vischini G et al. Increased plasma levels of tacrolimus after ingestion of green tea. 2011 Am. J. Kidney Dis. pmid:21787983
van Duijnhoven EM et al. A late episode of post-transplant diabetes mellitus during active hepatitis C infection in a renal allograft recipient using tacrolimus. 2002 Am. J. Kidney Dis. pmid:12087579
Moes AD et al. Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial. 2017 Am. J. Kidney Dis. pmid:28259499
Wong KM et al. Abbreviated tacrolimus area-under-the-curve monitoring for renal transplant recipients. 2000 Am. J. Kidney Dis. pmid:10739787
Böhmig GA et al. Role of humoral immune reactions as target for antirejection therapy in recipients of a spousal-donor kidney graft. 2000 Am. J. Kidney Dis. pmid:10739788
Starzl TE et al. Tacrolimus (FK506) and the pharmaceutical/academic/regulatory gauntlet. 1998 Am. J. Kidney Dis. pmid:9631858
Li X et al. Tacrolimus therapy in adults with steroid- and cyclophosphamide-resistant nephrotic syndrome and normal or mildly reduced GFR. 2009 Am. J. Kidney Dis. pmid:19406543
Al-Awwa IA et al. Importance of allograft biopsy in renal transplant recipients: correlation between clinical and histological diagnosis. 1998 Am. J. Kidney Dis. pmid:9631859
Lum EL et al. Acute Kidney Allograft Rejection Precipitated by Lenalidomide Treatment for Multiple Myeloma. 2017 Am. J. Kidney Dis. pmid:28189378
Neylan JF et al. Assessment of the frequency and costs of posttransplantation hospitalizations in patients receiving tacrolimus versus cyclosporine. 1998 Am. J. Kidney Dis. pmid:9820446
Chen W et al. Short-term outcomes of induction therapy with tacrolimus versus cyclophosphamide for active lupus nephritis: A multicenter randomized clinical trial. 2011 Am. J. Kidney Dis. pmid:21177013
First MR Renal transplantation for the nephrologist: new immunosuppressive drugs. 1992 Am. J. Kidney Dis. pmid:1371201
Paoletti E et al. ACE inhibitors and persistent left ventricular hypertrophy after renal transplantation: a randomized clinical trial. 2007 Am. J. Kidney Dis. pmid:17591533
Mertz D et al. Drug-drug interaction in a kidney transplant recipient receiving HIV salvage therapy and tacrolimus. 2009 Am. J. Kidney Dis. pmid:19346040
Israni A et al. Conversion to tacrolimus for the treatment of cyclosporine-associated nephrotoxicity in heart transplant recipients. 2002 Am. J. Kidney Dis. pmid:11877596
Soi V et al. Altered mental status in a kidney transplant recipient receiving tacrolimus. 2008 Am. J. Kidney Dis. pmid:18155524
Reese PP et al. Automated Reminders and Physician Notification to Promote Immunosuppression Adherence Among Kidney Transplant Recipients: A Randomized Trial. 2017 Am. J. Kidney Dis. pmid:27940063
Mathis AS and Friedman GS Coadministration of digoxin with itraconazole in renal transplant recipients. 2001 Am. J. Kidney Dis. pmid:11157404
Tsinalis D et al. Acute renal failure in a renal allograft recipient treated with intravenous immunoglobulin. 2002 Am. J. Kidney Dis. pmid:12200824
Grinyó JM et al. Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial. 2017 Am. J. Kidney Dis. pmid:27889299
Lien YH Top 10 Things Primary Care Physicians Should Know About Maintenance Immunosuppression for Transplant Recipients. 2016 Am. J. Med. pmid:26714210
Bar J et al. Is immunosuppression therapy in renal allograft recipients teratogenic? A single-center experience. 2003 Am. J. Med. Genet. A pmid:12476448
Perez-Aytes A et al. In utero exposure to mycophenolate mofetil: a characteristic phenotype? 2008 Am. J. Med. Genet. A pmid:18074358
Chen W et al. Outcomes of tacrolimus therapy in adults with refractory membranous nephrotic syndrome: a prospective, multicenter clinical trial. 2013 Am. J. Med. Sci. pmid:22627258
Hsu MS et al. Clinical features and outcome of tuberculosis in solid organ transplant recipients. 2007 Am. J. Med. Sci. pmid:17700199
Ocampo-Garza J et al. Acquired Hyperpigmentation and Cicatricial Alopecia. 2016 Am. J. Med. Sci. pmid:27524226
Chen M et al. Tacrolimus combined with corticosteroids in treatment of nephrotic idiopathic membranous nephropathy: a multicenter randomized controlled trial. 2010 Am. J. Med. Sci. pmid:20220333
Esposito C et al. Sirolimus prevents short-term renal changes induced by ischemia-reperfusion injury in rats. 2011 Am. J. Nephrol. pmid:21358177
Ren H et al. Tacrolimus versus cyclophosphamide in steroid-dependent or steroid-resistant focal segmental glomerulosclerosis: a randomized controlled trial. 2013 Am. J. Nephrol. pmid:23343906
Araujo LP et al. Interaction of the anti-inflammatory annexin A1 protein and tacrolimus immunosuppressant in the renal function of rats. 2010 Am. J. Nephrol. pmid:20484890
Fourtounas C et al. Different immunosuppressive combinations on T-cell regulation in renal transplant recipients. 2010 Am. J. Nephrol. pmid:20484893
Bhimma R et al. Management of steroid-resistant focal segmental glomerulosclerosis in children using tacrolimus. 2006 Am. J. Nephrol. pmid:17159342
Ferreira A et al. Donor-Specific Anti-Human Leukocyte Antigens Antibodies, Acute Rejection, Renal Function, and Histology in Kidney Transplant Recipients Receiving Tacrolimus and Everolimus. 2017 Am. J. Nephrol. pmid:28511172
Tsipotis E et al. Bioavailability, Efficacy and Safety of Generic Immunosuppressive Drugs for Kidney Transplantation: A Systematic Review and Meta-Analysis. 2016 Am. J. Nephrol. pmid:27576318
Issa N et al. Calcineurin inhibitor nephrotoxicity: a review and perspective of the evidence. 2013 Am. J. Nephrol. pmid:23796509
Taber DJ et al. Significant racial differences in the key factors associated with early graft loss in kidney transplant recipients. 2014 Am. J. Nephrol. pmid:24969370
Vural A et al. Assessment of oxidative stress in the early posttransplant period: comparison of cyclosporine A and tacrolimus-based regimens. 2005 May-Jun Am. J. Nephrol. pmid:15925859
Zhang Q et al. Tacrolimus improves the proteinuria remission in patients with refractory IgA nephropathy. 2012 Am. J. Nephrol. pmid:22456060
Li J et al. Evaluation of mycophenolic acid exposure using a limited sampling strategy in renal transplant recipients. 2013 Am. J. Nephrol. pmid:23689735
Lee CT et al. Effects of cyclosporine, tacrolimus and rapamycin on renal calcium transport and vitamin D metabolism. 2011 Am. J. Nephrol. pmid:21691056
Soubhia RM et al. Tacrolimus and nonsteroidal anti-inflammatory drugs: an association to be avoided. 2005 Jul-Aug Am. J. Nephrol. pmid:15976495
Dai DS et al. Protective Effect of Salvia Przewalskii Extract on Puromycin-Induced Podocyte Injury. 2015 Am. J. Nephrol. pmid:26439819
El-Dahshan KF et al. Ketoconazole-tacrolimus coadministration in kidney transplant recipients: two-year results of a prospective randomized study. 2006 Am. J. Nephrol. pmid:16804292
Jin J et al. Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway. 2016 Am. J. Nephrol. pmid:27174564
Weir MR et al. Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function. 2004 Jul-Aug Am. J. Nephrol. pmid:15237243
Bagnis C et al. Comparative acute nephrotoxicity of FK-506 and ciclosporin in an isolated in situ autoperfused rat kidney model. 1997 Am. J. Nephrol. pmid:9057948
von Felbert V et al. Squamous cell carcinoma arising from a localized vulval lesion of Hailey-Hailey disease after tacrolimus therapy. 2010 Am. J. Obstet. Gynecol. pmid:20816142
Kauppila S et al. The effect of topical pimecrolimus on inflammatory infiltrate in vulvar lichen sclerosus. 2010 Am. J. Obstet. Gynecol. pmid:19889396
Jensen JT et al. Patient satisfaction after the treatment of vulvovaginal erosive lichen planus with topical clobetasol and tacrolimus: a survey study. 2004 Am. J. Obstet. Gynecol. pmid:15284791
Marquezan MC et al. Effect of Topical Tacrolimus in the Treatment of Thygeson's Superficial Punctate Keratitis. 2015 Am. J. Ophthalmol. pmid:26133248
Ciardella AP et al. Cytomegalovirus retinitis and FK 506. 2003 Am. J. Ophthalmol. pmid:12888078
Goldberg NR et al. Success with single-agent immunosuppression for multifocal choroidopathies. 2014 Am. J. Ophthalmol. pmid:25194229
Al-Amri AM Long-term follow-up of tacrolimus ointment for treatment of atopic keratoconjunctivitis. 2014 Am. J. Ophthalmol. pmid:24439439
Rikkers SM et al. Topical tacrolimus treatment of atopic eyelid disease. 2003 Am. J. Ophthalmol. pmid:12614745
Yen MT et al. Oscillopsia and pseudonystagmus in kidney transplant patients. 1999 Am. J. Ophthalmol. pmid:10612521
Mochizuki M et al. A clinical trial of FK506 in refractory uveitis. 1993 Am. J. Ophthalmol. pmid:7685147
Brazis PW et al. A case of bilateral optic neuropathy in a patient on tacrolimus (FK506) therapy after liver transplantation. 2000 Am. J. Ophthalmol. pmid:10764869
Jung JW et al. Long-term result of maintenance treatment with tacrolimus ointment in chronic ocular graft-versus-host disease. 2015 Am. J. Ophthalmol. pmid:25498356
Ishioka M et al. FK506 treatment of noninfectious uveitis. 1994 Am. J. Ophthalmol. pmid:7526689
Lee YJ et al. Application for tacrolimus ointment in treating refractory inflammatory ocular surface diseases. 2013 Am. J. Ophthalmol. pmid:23394907
Moriya K et al. Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells. 2009 Am. J. Pathol. pmid:19729476
Lin Y et al. PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases. 2014 Am. J. Pathol. pmid:24269558
Maurer M et al. Hair growth modulation by topical immunophilin ligands: induction of anagen, inhibition of massive catagen development, and relative protection from chemotherapy-induced alopecia. 1997 Am. J. Pathol. pmid:9094998
Bröcker V et al. Arteriolar lesions in renal transplant biopsies: prevalence, progression, and clinical significance. 2012 Am. J. Pathol. pmid:22464889
Zager RA et al. Renal cholesterol accumulation: a durable response after acute and subacute renal insults. 2001 Am. J. Pathol. pmid:11485932
Lunz JG et al. Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection: increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs. 2001 Am. J. Pathol. pmid:11290556
Sohn HW et al. Engagement of CD99 induces apoptosis through a calcineurin-independent pathway in Ewing's sarcoma cells. 1998 Am. J. Pathol. pmid:9846983
Langer A et al. Humoral and cellular immunopathology of hepatic and cardiac hamster-into-rat xenograft rejection. Marked stimulation of IgM++bright/IgD+dull splenic B cells. 1993 Am. J. Pathol. pmid:7686346
Ito T et al. Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model. 2004 Am. J. Pathol. pmid:14742267
Rokaw MD et al. FK-506 and rapamycin but not cyclosporin inhibit aldosterone-stimulated sodium transport in A6 cells. 1996 Am. J. Physiol. pmid:8760046
Tumlin JA et al. Expression of calcineurin activity and alpha-subunit isoforms in specific segments of the rat nephron. 1995 Am. J. Physiol. pmid:7485542
duBell WH et al. Independent inhibition of calcineurin and K+ currents by the immunosuppressant FK-506 in rat ventricle. 1998 Am. J. Physiol. pmid:9843803
Aoki Y et al. CsA-sensitive purine-box transcriptional regulator in bronchial epithelial cells contains NF45, NF90, and Ku. 1998 Am. J. Physiol. pmid:9843854
Kanoh S et al. Effect of FK506 on ATP-induced intracellular calcium oscillations in cow tracheal epithelium. 1999 Am. J. Physiol. pmid:10362712
Bragado MJ et al. p70s6k is activated by CCK in rat pancreatic acini. 1997 Am. J. Physiol. pmid:9252447
Shah AU et al. Protease activation during in vivo pancreatitis is dependent on calcineurin activation. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20501444
Yamada T et al. Role of T cells in development of chronic pancreatitis in male Wistar Bonn/Kobori rats: effects of tacrolimus. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11705744
Husain SZ et al. Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17332472
Tashiro M et al. Calcineurin mediates pancreatic growth in protease inhibitor-treated mice. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14684381
Gao G et al. Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21357511
DuBell WH et al. K(+) currents responsible for repolarization in mouse ventricle and their modulation by FK-506 and rapamycin. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10710358
Giordano A et al. Differential effect of atorvastatin and tacrolimus on proliferation of vascular smooth muscle and endothelial cells. 2012 Am. J. Physiol. Heart Circ. Physiol. pmid:22058159
Ogino A et al. Amlodipine inhibits granulation tissue cell apoptosis through reducing calcineurin activity to attenuate postinfarction cardiac remodeling. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17644576
Balasubramaniam R et al. Caffeine-induced arrhythmias in murine hearts parallel changes in cellular Ca(2+) homeostasis. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15923307
Giordano A et al. Rapamycin antagonizes NF-kappaB nuclear translocation activated by TNF-alpha in primary vascular smooth muscle cells and enhances apoptosis. 2006 Am. J. Physiol. Heart Circ. Physiol. pmid:16428340
Kraiss LW et al. Fluid flow activates a regulator of translation, p70/p85 S6 kinase, in human endothelial cells. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10775131
Tang WX et al. Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscle. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:11893565
Liu Y et al. Transcription factor CHF1/Hey2 regulates EC coupling and heart failure in mice through regulation of FKBP12.6. 2012 Am. J. Physiol. Heart Circ. Physiol. pmid:22408025