tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fisher NC | Renal failure after lung transplantation. | 1998 | Lancet | pmid:9800782 |
| Garcia-Criado FJ et al. | Possible tacrolimus action mechanisms in its protector effects on ischemia-reperfusion injury. | 1998 | Transplantation | pmid:9798713 |
| Sankary HN et al. | FK506 treatment in combination with leflunomide in hamster-to-rat heart and liver xenograft transplantation. | 1998 | Transplantation | pmid:9798690 |
| Whitcup SM et al. | Topical liposome-encapsulated FK506 for the treatment of endotoxin-induced uveitis. | 1998 | Ocul. Immunol. Inflamm. | pmid:9798194 |
| Schaefer A et al. | Stimulation of the Ca2+-mediated egr-1 and c-fos expression in murine erythroleukaemia cells by cyclosporin A. | 1998 | Biochem. J. | pmid:9794788 |
| Kobayashi M et al. | Effects of FK506 on experimental membranous glomerulonephritis induced by cationized bovine serum albumin in rats. | 1998 | Nephrol. Dial. Transplant. | pmid:9794552 |
| Hashimoto Y et al. | Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats. | 1998 | Pharm. Res. | pmid:9794505 |
| Sengoku T et al. | [Effects of tacrolimus ointment on type I (immediate and late) and IV (delayed) cutaneous allergic reactions in mice]. | 1998 | Nippon Yakurigaku Zasshi | pmid:9793077 |
| Toshima K et al. | Effect of FK506 on the activation state of hepatic macrophages in Propionibacterium acnes-treated rats. | 1998 | J. Gastroenterol. Hepatol. | pmid:9792034 |
| Casavilla FA et al. | Clinical outcome of patients infected with hepatitis C virus infection on survival after primary liver transplantation under tacrolimus. | 1998 | Liver Transpl Surg | pmid:9791154 |
| Ohye H et al. | Effects of immunosuppressant agents on growth hormone release and gene expression. | 1998 | Endocr. J. | pmid:9790238 |
| Bajaj-Elliott M et al. | Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia. | 1998 | J. Clin. Invest. | pmid:9788959 |
| Masugi T and Otsuka K | [Immunosuppressive drugs and calcineurin]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9788176 |
| Heering P et al. | Distal tubular acidosis induced by FK506. | 1998 | Clin Transplant | pmid:9787958 |
| Wu A et al. | Outcome of 22 successful pregnancies after liver transplantation. | 1998 | Clin Transplant | pmid:9787957 |
| Peddi VR et al. | Use of tacrolimus eliminates acute rejection as a major complication following simultaneous kidney and pancreas transplantation. | 1998 | Clin Transplant | pmid:9787948 |
| Rayes N et al. | Pregnancies following liver transplantation--how safe are they? A report of 19 cases under cyclosporine A and tacrolimus. | 1998 | Clin Transplant | pmid:9787947 |
| Nishida T et al. | [FK506 for the prophylaxis of graft-versus-host-disease after bone marrow transplantation from HLA-genotypically mismatched unrelated donor]. | 1998 | Rinsho Ketsueki | pmid:9785975 |
| Maestri M et al. | [Treatment of the nephrotoxicity of immunosuppressive drugs with insulin-like growth factor-I]. | 1998 | Minerva Chir | pmid:9780630 |
| Motamedi H and Shafiee A | The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. | 1998 | Eur. J. Biochem. | pmid:9780228 |