Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Neylan JF et al. | Assessment of the frequency and costs of posttransplantation hospitalizations in patients receiving tacrolimus versus cyclosporine. | 1998 | Am. J. Kidney Dis. | pmid:9820446 |
Igarashi K et al. | A novel indication of the activities of small molecule inhibitors of protein-protein interactions: application of the yeast two-hybrid system. | 1998 | J. Antibiot. | pmid:9820241 |
Campo JV et al. | Tacrolimus toxic reaction associated with the use of nefazodone: paroxetine as an alternative agent. | 1998 | Arch. Gen. Psychiatry | pmid:9819077 |
Perego C et al. | Evidence that SMS 201-995 enhances the immunosuppressive effect of FK506. | 1998 | Int. J. Immunopharmacol. | pmid:9818792 |
Ader JL and Rostaing L | Cyclosporin nephrotoxicity: pathophysiology and comparison with FK-506. | 1998 | Curr. Opin. Nephrol. Hypertens. | pmid:9818201 |
Wells WA | Coming full circle. Vertex Pharmaceuticals, Inc. | 1998 | Chem. Biol. | pmid:9818152 |
Shapiro R et al. | A prospective, randomized trial to compare tacrolimus and prednisone with and without mycophenolate mofetil in patients undergoing renal transplantation: first report. | 1998 | J. Urol. | pmid:9817305 |
Bachinger A et al. | [Immunosuppression with tacrolimus (FK 506) and cyclosporin A for preventing graft rejection after liver transplantation. Retrospective evaluation of medical costs based on the FG-O157 Study in 224 patients (Germany)]. | 1998 | Chirurg | pmid:9816454 |
Walder B et al. | Tacrolimus (FK 506)-induced hemolytic uremic syndrome after heart transplantation. | 1998 | J. Heart Lung Transplant. | pmid:9811409 |
Marton MJ et al. | Drug target validation and identification of secondary drug target effects using DNA microarrays. | 1998 | Nat. Med. | pmid:9809554 |