Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Makowka L et al. | The effect of FK-506 on hyperacute rejection in presensitized rats. | 1987 | Transplant. Proc. | pmid:2445082 |
Ochiai T et al. | Effects of FK-506 on xenotransplantation of the heart and skin in a mouse-rat combination. | 1987 | Transplant. Proc. | pmid:2445083 |
Nalesnik MA et al. | Toxicology of FK-506 in the Lewis rat. | 1987 | Transplant. Proc. | pmid:2445084 |
Ochiai T et al. | Histopathologic studies in renal transplant recipient dogs receiving treatment with FK-506. | 1987 | Transplant. Proc. | pmid:2445085 |
Thiru S et al. | Pathological studies in canine and baboon renal allograft recipients immunosuppressed with FK-506. | 1987 | Transplant. Proc. | pmid:2445086 |
Kino T et al. | FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. | 1987 | J. Antibiot. | pmid:2445721 |
Kino T et al. | FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. | 1987 | J. Antibiot. | pmid:2445722 |
Sawada S et al. | Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation. | 1987 | J. Immunol. | pmid:2442255 |
Qu W et al. | Correlation Between Immunosuppressive Therapy and CD4(+) T-Cell Intracellular Adenosine Triphosphate Levels in Liver Transplant Recipients. | Transplant. Proc. | pmid:27569951 | |
Mlinšek G et al. | The role of single nucleotide polymorphisms of CYP3A and ABCB1 on tacrolimus predose concentration in kidney transplant recipients. | Clin. Nephrol. | pmid:28655393 | |
Bonatti HJR et al. | Clostridium difficile-Associated Colitis Post-Transplant Is Not Associated with Elevation of Tacrolimus Concentrations. | Surg Infect (Larchmt) | pmid:28650734 | |
Liendo VL et al. | Topical tacrolimus for the treatment of severe allergic keratoconjunctivitis in children. | Arq Bras Oftalmol | pmid:28954018 | |
Johnson JL et al. | Pyoderma gangrenosum associated with an aseptic splenic abscess in a patient with neurofibromatosis. | Pediatr Dermatol | pmid:23535023 | |
Moreno Gonzales M et al. | Sublingual Tacrolimus in Liver Transplantation: A Valid Option? | Transplant. Proc. | pmid:27569953 | |
Ming M et al. | Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response. | Photochem. Photobiol. | pmid:25039758 | |
pmid: | ||||
pmid:28951508 | ||||
pmid:28761977 | ||||
Malik S et al. | Disseminated infection in a kidney-pancreas transplant recipient: A case report and review of the literature. | Saudi J Kidney Dis Transpl | pmid:27900974 | |
Tan GF et al. | Anogenital epidermolytic acanthomas: effective treatment of pruritus with 0.1% tacrolimus ointment. | Dermatol Ther | pmid:24703270 |