tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pompeo A et al. | Cyclosporin A, but not FK506, increases arachidonic acid release and inhibits proliferation of pituitary corticotrope tumor cells. | 1999 | Life Sci. | pmid:10096434 |
| Nogueira JM et al. | A comparison of recipient renal outcomes with laparoscopic versus open live donor nephrectomy. | 1999 | Transplantation | pmid:10096529 |
| Shapiro R et al. | Posttransplant diabetes in pediatric recipients on tacrolimus. | 1999 | Transplantation | pmid:10096540 |
| Hemenway CS and Heitman J | Calcineurin. Structure, function, and inhibition. | 1999 | Cell Biochem. Biophys. | pmid:10099825 |
| Holländer GA et al. | Molecular and biological actions of cyclosporin A and FK506 on T cell development and function. | 1994 | Transfus Sci | pmid:10155542 |
| Antoniou EA et al. | Immunosuppressive effect of combination schedules of brequinar with leflunomide or tacrolimus on rat cardiac allotransplantation. | 1999 | Microsurgery | pmid:10188834 |
| Yasutsune T et al. | Vasorelaxation and inhibition of the voltage-operated Ca2+ channels by FK506 in the porcine coronary artery. | 1999 | Br. J. Pharmacol. | pmid:10188984 |
| Zhang W et al. | Failure of calcineurin inhibitors to prevent pressure-overload left ventricular hypertrophy in rats. | 1999 | Circ. Res. | pmid:10189360 |
| Fansa H et al. | The effect of the immunosuppressant FK 506 on peripheral nerve regeneration following nerve grafting. | 1999 | J Hand Surg Br | pmid:10190602 |
| Meiser BM et al. | Combination therapy with tacrolimus and mycophenolate mofetil following cardiac transplantation: importance of mycophenolic acid therapeutic drug monitoring. | 1999 | J. Heart Lung Transplant. | pmid:10194038 |
| Azuma N et al. | Immunosuppression with FK506 in rat arterial allografts: fate of allogeneic endothelial cells. | 1999 | J. Vasc. Surg. | pmid:10194498 |
| Mollison KW et al. | Discovery of ascomycin analogs with potent topical but weak systemic activity for treatment of inflammatory skin diseases. | 1998 | Curr. Pharm. Des. | pmid:10197049 |
| De Lima JJ et al. | Effects of FK506 in rat and human resistance arteries. | 1999 | Kidney Int. | pmid:10201018 |
| Sloper CM et al. | Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine. | 1999 | Ophthalmology | pmid:10201592 |
| Nagasaki Y et al. | Reversal of hypopigmentation in phenylketonuria mice by adenovirus-mediated gene transfer. | 1999 | Pediatr. Res. | pmid:10203136 |
| Hortelano S et al. | Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages. | 1999 | Br. J. Pharmacol. | pmid:10205001 |
| Cetinkale O et al. | Modulating the functions of neutrophils and lipid peroxidation by FK506 in a rat model of thermal injury. | 1999 | Burns | pmid:10208383 |
| Lütkes P et al. | [Quality of life following transplantation. The impact ofa new immunosuppressive substance]. | 1999 | Zentralbl Chir | pmid:10209841 |
| Jani A et al. | Modulation of cell-mediated immunity prolongs adenovirus-mediated transgene expression in sciatic nerve. | 1999 | Hum. Gene Ther. | pmid:10210146 |
| Knoll GA and Bell RC | Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials. | 1999 | BMJ | pmid:10213717 |