tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Srivastava M et al. | Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child. | 1998 | Gastroenterology | pmid:9721172 |
| Yang X et al. | Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. | 1998 | Science | pmid:9721101 |
| Jacobson P et al. | Tacrolimus: a new agent for the prevention of graft-versus-host disease in hematopoietic stem cell transplantation. | 1998 | Bone Marrow Transplant. | pmid:9720734 |
| Tao HR | FK506 inhibits severe graft-versus-host disease without mediating the involvement of perforin and granzyme B. | 1998 | Hokkaido Igaku Zasshi | pmid:9719949 |
| Fukuda K et al. | cFKBP/SMAP; a novel molecule involved in the regulation of smooth muscle differentiation. | 1998 | Development | pmid:9716519 |
| Tamura F et al. | FK506 promotes liver regeneration by suppressing natural killer cell activity. | 1998 | J. Gastroenterol. Hepatol. | pmid:9715421 |
| Iizuka K et al. | InsP3, but not novel Ca2+ releasers, contributes to agonist-initiated contraction in rabbit airway smooth muscle. | 1998 | J. Physiol. (Lond.) | pmid:9714870 |
| Zini R et al. | Tacrolimus decreases in vitro oxidative phosphorylation of mitochondria from rat forebrain. | 1998 | Life Sci. | pmid:9714423 |
| Shaw LM | Mycophenolate mofetil: pharmacokinetic strategies for optimizing immunosuppression. | 1997 | Drug Metabol Drug Interact | pmid:9713576 |
| Holt DW and Johnston A | Monitoring new immunosuppressive agents. Are the methods adequate? | 1997 | Drug Metabol Drug Interact | pmid:9713574 |
| Moreno M et al. | Monitoring of tacrolimus as rescue therapy in pediatric liver transplantation. | 1998 | Ther Drug Monit | pmid:9712459 |
| Marsaud V et al. | Dexamethasone and triamcinolone acetonide accumulation in mouse fibroblasts is differently modulated by the immunosuppressants cyclosporin A, FK506, rapamycin and their analogues, as well as by other P-glycoprotein ligands. | 1998 | J. Steroid Biochem. Mol. Biol. | pmid:9712407 |
| Ruetz S | Yeast secretory vesicle system for expression and functional characterization of P-glycoproteins. | 1998 | Meth. Enzymol. | pmid:9711569 |
| White MH et al. | Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia. | 1998 | Clin. Infect. Dis. | pmid:9709879 |
| Khattab A et al. | Cyclosporins: lack of correlation between antischistosomal properties and inhibition of cyclophilin isomerase activity. | 1998 | Exp. Parasitol. | pmid:9709036 |
| Ogawa T et al. | Osteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9705862 |
| Stone JH et al. | Outcome of renal transplantation in ninety-seven cyclosporine-era patients with systemic lupus erythematosus and matched controls. | 1998 | Arthritis Rheum. | pmid:9704643 |
| Xu M et al. | Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation. | 1998 | Transpl. Int. | pmid:9704394 |
| Garg UC et al. | Comparison of the Abbott IMx Tacrolimus I and Tacrolimus II assays. | 1998 | Clin. Chem. | pmid:9702984 |
| Gruessner RW et al. | Donor-specific portal blood transfusion in intestinal transplantation: a prospective, preclinical large animal study. | 1998 | Transplantation | pmid:9701258 |