tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Abu Zaid M et al. | Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT. | 2017 | Blood | pmid:27827824 |
| Nazmul MN et al. | Severe Hyperkalemia Complicating Voriconazole Treatment in a Kidney Transplant Recipient With Histoplasmosis: A Case Report. | 2017 | Transplant. Proc. | pmid:29198681 |
| Berisa Prado S et al. | Topical Tacrolimus for Corneal Subepithelial Infiltrates Secondary to Adenoviral Keratoconjunctivitis. | 2017 | Cornea | pmid:28704319 |
| Lloberas N et al. | The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation. | 2017 | Pharmacogenet. Genomics | pmid:28704257 |
| Saito R et al. | Two cases of eczematous drug eruption caused by oral tacrolimus administration. | 2017 | Contact Derm. | pmid:28703346 |
| Hirai T et al. | The effectiveness of new triple combination therapy using synthetic disease-modifying anti-rheumatic drugs with different pharmacological function against rheumatoid arthritis: the verification by an in vitro and clinical study. | 2017 | Clin. Rheumatol. | pmid:27783236 |
| Lee JE et al. | A Case of Rheumatoid Vasculitis Involving Hepatic Artery in Early Rheumatoid Arthritis. | 2017 | J. Korean Med. Sci. | pmid:28581281 |
| Riva N et al. | Pharmacoepidemiology of tacrolimus in pediatric liver transplantation. | 2017 | Pediatr Transplant | pmid:28574195 |
| Wu H et al. | Novel self-assembled tacrolimus nanoparticles cross-linking thermosensitive hydrogels for local rheumatoid arthritis therapy. | 2017 | Colloids Surf B Biointerfaces | pmid:27736727 |
| Damon C et al. | Predictive Modeling of Tacrolimus Dose Requirement Based on High-Throughput Genetic Screening. | 2017 | Am. J. Transplant. | pmid:27597269 |
| Donati M et al. | Resolution of Benign and Malignant Sebaceous Neoplasms, in a Renal Transplant Patient Treated With Everolimus. | 2017 | Exp Clin Transplant | pmid:25924010 |
| Kim YJ et al. | Two cases of hydroa vacciniforme-like lymphoproliferative disease controlled by anti-inflammatory agents. | 2017 | Photodermatol Photoimmunol Photomed | pmid:28543883 |
| Zong YP et al. | Effects of CYP3A5 polymorphisms on tacrolimus pharmacokinetics in pediatric kidney transplantation: a systematic review and meta-analysis of observational studies. | 2017 | World J Pediatr | pmid:28540692 |
| Gooptu M and Koreth J | Better acute graft--host disease outcomes for allogeneic transplant recipients in the modern era: a tacrolimus effect? | 2017 | Haematologica | pmid:28458253 |
| Costa JS et al. | Polyomavirus Nephropathy: Ten-Year Experience. | 2017 | Transplant. Proc. | pmid:28457399 |
| Ren S et al. | Comparative effectiveness and tolerance of immunosuppressive treatments for idiopathic membranous nephropathy: A network meta-analysis. | 2017 | PLoS ONE | pmid:28898290 |
| Chiasson VL et al. | Regulatory T-Cell Augmentation or Interleukin-17 Inhibition Prevents Calcineurin Inhibitor-Induced Hypertension in Mice. | 2017 | Hypertension | pmid:28584011 |
| Shoda W et al. | Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake. | 2017 | Kidney Int. | pmid:28341239 |
| Cakir U et al. | Role of Everolimus on Cardiac Functions in Kidney Transplant Recipients. | 2017 | Transplant. Proc. | pmid:28340820 |
| Hettiarachchi PVKS et al. | Comparison of topical tacrolimus and clobetasol in the management of symptomatic oral lichen planus: A double-blinded, randomized clinical trial in Sri Lanka. | 2017 | J Investig Clin Dent | pmid:27633647 |
| Ciftci HS et al. | Influence of Proton Pump Inhibitors on Mycophenolic Acid Pharmacokinetics in Patients With Renal Transplantation and the Relationship With Cytochrome 2C19 Gene Polymorphism. | 2017 | Transplant. Proc. | pmid:28340819 |
| Zhu J et al. | Granzyme B producing B-cells in renal transplant patients. | 2017 | Clin. Immunol. | pmid:28461110 |
| Rodrigues N et al. | Serum Magnesium and Related Factors in Long-Term Renal Transplant Recipients: An Observational Study. | 2017 | Transplant. Proc. | pmid:28457398 |
| Terada Y et al. | Tacrolimus Triggers Transient Receptor Potential Vanilloid-1-Dependent Relapse of Pancreatitis-Related Pain in Mice. | 2017 | Pharmacology | pmid:28253495 |
| Zhang X et al. | Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients. | 2017 | Dis. Markers | pmid:28246425 |
| Mashayekhi S et al. | The treatment of vulval lichen sclerosus in prepubertal girls: a critically appraised topic. | 2017 | Br. J. Dermatol. | pmid:28244087 |
| Guttman-Yassky E et al. | Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis. | 2017 | J. Allergy Clin. Immunol. | pmid:28238742 |
| Kanai T et al. | Adequate tacrolimus concentration for myasthenia gravis treatment. | 2017 | Eur. J. Neurol. | pmid:28102047 |
| Sarier M et al. | HPV type 45-positive condyloma acuminata of the bladder in a renal transplant recipient. | 2017 | Transpl Infect Dis | pmid:28100036 |
| Fan B et al. | Prograf produces more benefits for CYP3A5 low expression patients in early stage after kidney transplantation. | 2017 | Biomed. Pharmacother. | pmid:28157649 |
| Juvvadi PR et al. | Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach. | 2017 | Virulence | pmid:27325145 |
| D'Avola D et al. | Cardiovascular morbidity and mortality after liver transplantation: The protective role of mycophenolate mofetil. | 2017 | Liver Transpl. | pmid:28160394 |
| Andreu F et al. | A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach. | 2017 | Clin Pharmacokinet | pmid:28050888 |
| Shimizu K | Development of New Liposome Targeting Strategies for Application of Disease Therapies. | 2017 | Yakugaku Zasshi | pmid:28049894 |
| Cukor D et al. | A Pilot Randomized Controlled Trial to Promote Immunosuppressant Adherence in Adult Kidney Transplant Recipients. | 2017 | Nephron | pmid:28049201 |
| Maneechote C et al. | Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury. | 2017 | J. Cell. Mol. Med. | pmid:28941171 |
| Baskiran A et al. | Pregnancy After Liver Transplantation: Risks and Outcomes. | 2017 | Transplant. Proc. | pmid:28923640 |
| Shi G et al. | Variation of CD4CD25Foxp3 Regulatory T Cells and Th17 Cells in the Peripheral Blood of Human Liver Allograft Patients With Long-term Survival. | 2017 | Transplant. Proc. | pmid:28923634 |
| Reese PP et al. | Automated Reminders and Physician Notification to Promote Immunosuppression Adherence Among Kidney Transplant Recipients: A Randomized Trial. | 2017 | Am. J. Kidney Dis. | pmid:27940063 |
| Shrestha BM | Two Decades of Tacrolimus in Renal Transplant: Basic Science and Clinical Evidences. | 2017 | Exp Clin Transplant | pmid:27938316 |
| Weininger U et al. | Dynamics of Aromatic Side Chains in the Active Site of FKBP12. | 2017 | Biochemistry | pmid:27936610 |
| Gonzalez-Andrades M et al. | Sterile Corneal Infiltrates Secondary to Psoriasis Exacerbations: Topical Tacrolimus as an Alternative Treatment Option. | 2017 | Eye Contact Lens | pmid:26222098 |
| Božina N et al. | Steady-state pharmacokinetics of mycophenolic acid in renal transplant patients: exploratory analysis of the effects of cyclosporine, recipients' and donors' ABCC2 gene variants, and their interactions. | 2017 | Eur. J. Clin. Pharmacol. | pmid:28624888 |
| Olmedo MartÃn RV et al. | Medium to long-term efficacy and safety of oral tacrolimus in moderate to severe steroid refractory ulcerative colitis. | 2017 | Rev Esp Enferm Dig | pmid:28617029 |
| Pathak S et al. | Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice. | 2017 | Drug Deliv | pmid:28911248 |
| Maldonado AQ et al. | Prevalence of CYP3A5 Genomic Variances and Their Impact on Tacrolimus Dosing Requirements among Kidney Transplant Recipients in Eastern North Carolina. | 2017 | Pharmacotherapy | pmid:28605053 |
| Chucair-Elliott AJ et al. | Colony Stimulating Factor-1 Receptor Expressing Cells Infiltrating the Cornea Control Corneal Nerve Degeneration in Response to HSV-1 Infection. | 2017 | Invest. Ophthalmol. Vis. Sci. | pmid:28903153 |
| Esquirol A et al. | Single-agent GvHD prophylaxis with tacrolimus after post-transplant high-dose cyclophosphamide is a valid option for haploidentical transplantation in adults with hematological malignancies. | 2017 | Bone Marrow Transplant. | pmid:28604667 |
| Zhang W et al. | Isoglycyrrhizinate Magnesium Enhances Hepatoprotective Effect of FK506 on Ischemia-Reperfusion Injury Through HMGB1 Inhibition in a Rat Model of Liver Transplantation. | 2017 | Transplantation | pmid:28885495 |
| Pietrosi G and Chinnici C | Report on Liver Cell Transplantation Using Human Fetal Liver Cells. | 2017 | Methods Mol. Biol. | pmid:27830561 |