Thomson AW et al. |
FK 506: a novel immunosuppressant for treatment of autoimmune disease. Rationale and preliminary clinical experience at the University of Pittsburgh. |
1993 |
Springer Semin. Immunopathol. |
pmid:7686690
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Ueno M et al. |
[Immunosuppressive effect in combination therapy of cyclosporine A, FK506 and 15-deoxyspergualin on a pancreatic islet xenotransplantation]. |
1993 |
Nihon Geka Gakkai Zasshi |
pmid:7686615
|
Fujisawa T et al. |
Dose study of the immunosuppression of FK 506 in canine lung allo-transplantation. |
1993 |
Surg. Today |
pmid:7686416
|
Langer A et al. |
Humoral and cellular immunopathology of hepatic and cardiac hamster-into-rat xenograft rejection. Marked stimulation of IgM++bright/IgD+dull splenic B cells. |
1993 |
Am. J. Pathol. |
pmid:7686346
|
Calne RY et al. |
Intestinal transplant for recurring mesenteric desmoid tumour. |
1993 |
Lancet |
pmid:7686241
|
Sakr MF et al. |
FK 506 pre-treatment is associated with reduced levels of tumor necrosis factor and interleukin 6 following hepatic ischemia/reperfusion. |
1993 |
J. Hepatol. |
pmid:7686193
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Wong PY et al. |
Recurrence of primary biliary cirrhosis after liver transplantation following FK506-based immunosuppression. |
1993 |
J. Hepatol. |
pmid:7686192
|
Li W and Handschumacher RE |
Specific interaction of the cyclophilin-cyclosporin complex with the B subunit of calcineurin. |
1993 |
J. Biol. Chem. |
pmid:7686148
|
Murphy MP and Morris RE |
Brequinar sodium effectively and potently suppresses allograft rejection in a heterotopic mouse heart transplant model. |
1993 |
Transplant. Proc. |
pmid:7685955
|
Takaya S et al. |
Use of prostaglandin E1 in crossmatch-negative liver transplant recipients treated with FK 506. |
1993 |
Transplant. Proc. |
pmid:7685953
|
Moutabarrik A et al. |
Effect of FK 506 and cyclosporine on the expression of IL-6 and its receptor on stimulated monocytes. |
1993 |
Transplant. Proc. |
pmid:7685949
|
Moutabarrik A et al. |
Use of FK 506 in kidney transplantation. |
1993 |
Transplant. Proc. |
pmid:7685946
|
Textor SC et al. |
Systemic and renal hemodynamic differences between FK506 and cyclosporine in liver transplant recipients. |
1993 |
Transplantation |
pmid:7685934
|
McDiarmid SV et al. |
Differences in oral FK506 dose requirements between adult and pediatric liver transplant patients. |
1993 |
Transplantation |
pmid:7685933
|
Suzuki S et al. |
Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. |
1993 |
Transplantation |
pmid:7685932
|
Sykes K et al. |
Proline isomerases function during heat shock. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7685914
|
Partaledis JA and Berlin V |
The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7685904
|
Akamine S et al. |
[Effect of FK-506 on bronchial healing of canine lung allografts]. |
1993 |
Nihon Kyobu Geka Gakkai Zasshi |
pmid:7685803
|
Pilot-Matias TJ et al. |
High-level synthesis of the 12-kDa human FK506-binding protein in Escherichia coli using translational coupling. |
1993 |
Gene |
pmid:7685727
|
Wagner JA et al. |
Failure of FK 506 to suppress the T cell-mediated immunity of mice to Listeria monocytogenes. |
1993 |
Clin. Exp. Immunol. |
pmid:7685672
|
Sewell KL |
Immunotherapy and other novel therapies, including biologic response modifiers, apheresis, and dietary modifications. |
1993 |
Curr Opin Rheumatol |
pmid:7685614
|
Ahmed SS et al. |
Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes. |
1993 |
J. Pharmacol. Exp. Ther. |
pmid:7685382
|
Bumgardner GL and Roberts JP |
New immunosuppressive agents. |
1993 |
Gastroenterol. Clin. North Am. |
pmid:7685324
|
Metcalfe S et al. |
Prodigiosin 25C: effect in in vitro models for T cell activation and T cell cycling and in vivo for rat heart allografts. |
1993 |
Int. Arch. Allergy Immunol. |
pmid:7685216
|
Asami M et al. |
Detection of the FK506-FKBP-calcineurin complex by a simple binding assay. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7685169
|
Ocain TD et al. |
A nonimmunosuppressive triene-modified rapamycin analog is a potent inhibitor of peptidyl prolyl cis-trans isomerase. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7685167
|
Mochizuki M et al. |
A clinical trial of FK506 in refractory uveitis. |
1993 |
Am. J. Ophthalmol. |
pmid:7685147
|
Wallemacq PE et al. |
Improvement and assessment of enzyme-linked immunosorbent assay to detect low FK506 concentrations in plasma or whole blood within 6 hours. |
1993 |
Clin. Chem. |
pmid:7684956
|
Connelly PR et al. |
Probing hydration contributions to the thermodynamics of ligand binding by proteins. Enthalpy and heat capacity changes of tacrolimus and rapamycin binding to FK506 binding protein in D2O and H2O. |
1993 |
Biochemistry |
pmid:7684925
|
Francavilla A et al. |
Hepatic regeneration and growth factors. |
1993 |
J Surg Oncol Suppl |
pmid:7684910
|
Dickey JB et al. |
Periocular FK-506 delays allograft rejection in rat penetrating keratoplasty. |
1993 |
Cornea |
pmid:7684663
|
Becker JW et al. |
FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. |
1993 |
J. Biol. Chem. |
pmid:7684380
|
Shapiro R et al. |
FK 506 interaction with danazol. |
1993 |
Lancet |
pmid:7684106
|
Jachez B et al. |
Reversion of the P-glycoprotein-mediated multidrug resistance of cancer cells by FK-506 derivatives. |
1993 |
Anticancer Drugs |
pmid:7683935
|
Mukai H et al. |
FKBP12-FK506 complex inhibits phosphatase activity of two mammalian isoforms of calcineurin irrespective of their substrates or activation mechanisms. |
1993 |
J. Biochem. |
pmid:7683641
|
Natazuka T et al. |
FK506 and cyclosporin a regulate proliferation and proto-oncogene expression in HTLV-1-associated myelopathy/tropical-spastic-paraparesis-derived T cells. |
1993 |
Int. J. Cancer |
pmid:7683633
|
Ohnishi H et al. |
Natural killer cell may impair liver regeneration in fulminant hepatic failure. |
1993 |
Gastroenterol. Jpn. |
pmid:7683619
|
Ohtake M et al. |
Enhanced liver regeneration in rats treated with 15-deoxyspergualin alone and in combination with FK 506. |
1993 |
Gastroenterol. Jpn. |
pmid:7683616
|
Waschulewski IH et al. |
Effects of the immunosuppressants cyclosporin A and FK 506 on exocytosis in the rat exocrine pancreas in vitro. |
1993 |
Br. J. Pharmacol. |
pmid:7683567
|
Denesyuk AI et al. |
Structural similarity of the binding sites of cyclophilin A-cyclosporin A and FKBP-FK506 systems. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7683466
|
Kadmon M et al. |
Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile. |
1993 |
Gastroenterology |
pmid:7683296
|
Blaehr H et al. |
Acute effects of FK506 and cyclosporine A on cultured human proximal tubular cells. |
1993 |
Eur. J. Pharmacol. |
pmid:7683267
|
Kai N et al. |
Prevention of insulitis and diabetes in nonobese diabetic mice by administration of FK506. |
1993 |
Transplantation |
pmid:7682740
|
Emond JC et al. |
Improved results of living-related liver transplantation with routine application in a pediatric program. |
1993 |
Transplantation |
pmid:7682738
|
Murase N et al. |
Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs. |
1993 |
Transplantation |
pmid:7682735
|
Shorrock C and Neuberger J |
The changing face of liver transplantation. |
1993 |
Gut |
pmid:7682532
|
Hutchison KA et al. |
FK506 binding to the 56-kilodalton immunophilin (Hsp56) in the glucocorticoid receptor heterocomplex has no effect on receptor folding or function. |
1993 |
Biochemistry |
pmid:7682438
|
Rao PN et al. |
Prediction of early graft function by effluent levels of hyaluronic acid in clinical liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7682366
|
Yu Y et al. |
Mutagenicity of the new immunosuppressive drugs, FK 506, and spergualin. |
1993 |
Transplant. Proc. |
pmid:7682364
|
Meiser BM et al. |
Simvastatin decreases accelerated graft vessel disease after heart transplantation in an animal model. |
1993 |
Transplant. Proc. |
pmid:7682363
|
Woodle ES et al. |
FK 506 rescue therapy: the rapidity of rejection reversal is related to the subsequent development of CMV disease. |
1993 |
Transplant. Proc. |
pmid:7682360
|
Woodle ES et al. |
FK 506 rescue therapy: early conversion improves efficacy. |
1993 |
Transplant. Proc. |
pmid:7682359
|
Woodle ES et al. |
Recurrent rejection following FK 506 rescue therapy for acute hepatic allograft rejection. |
1993 |
Transplant. Proc. |
pmid:7682358
|
Klintmalm GB et al. |
Rejection: FK 506 for rescue or maintenance. |
1993 |
Transplant. Proc. |
pmid:7682356
|
Frank B et al. |
Neurotoxicity of FK 506 in liver transplant recipients. |
1993 |
Transplant. Proc. |
pmid:7682355
|
Wiesner RH et al. |
Early cellular rejection treated with high-dose intravenous corticosteroid therapy is associated with a decrease in the incidence of steroid-resistant rejection and graft failure from rejection. |
1993 |
Transplant. Proc. |
pmid:7682352
|
Lundemose AG et al. |
Chlamydia trachomatis Mip-like protein has peptidyl-prolyl cis/trans isomerase activity that is inhibited by FK506 and rapamycin and is implicated in initiation of chlamydial infection. |
1993 |
Mol. Microbiol. |
pmid:7682281
|
Winkler M et al. |
Anaemia associated with FK 506 immunosuppression. |
1993 |
Lancet |
pmid:7682273
|
Bruserud O and Pawelec G |
Cyclosporine A and FK506 show similar immunosuppressive effects on long-term in vitro T-cell proliferation. |
1993 |
Int. J. Immunopharmacol. |
pmid:7682202
|
Tanaka N et al. |
Regulation of liver regeneration by interleukin-2 and its inhibitors: cyclosporine A and FK 506. |
1993 |
Int. J. Immunopharmacol. |
pmid:7682200
|
Xu RX et al. |
1H, 13C, and 15N assignments and secondary structure of the FK506 binding protein when bound to ascomycin. |
1993 |
Biopolymers |
pmid:7682113
|
Rotonda J et al. |
Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis. |
1993 |
J. Biol. Chem. |
pmid:7681823
|
Doi R et al. |
Structural and functional changes of exocrine pancreas induced by FK506 in rats. |
1993 |
Gastroenterology |
pmid:7681795
|
Luan S et al. |
Immunosuppressants implicate protein phosphatase regulation of K+ channels in guard cells. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7681590
|
Nishinaka Y et al. |
Protective effect of FK506 on ischemia/reperfusion-induced myocardial damage in canine heart. |
1993 |
J. Cardiovasc. Pharmacol. |
pmid:7681507
|
Fujimura A et al. |
Chronopharmacokinetic study of a new immunosuppressive agent, FK 506, in mice. |
1993 |
Jpn. J. Pharmacol. |
pmid:7681489
|
Valdivia LA et al. |
Successful hamster-to-rat liver xenotransplantation under FK506 immunosuppression induces unresponsiveness to hamster heart and skin. |
1993 |
Transplantation |
pmid:7681230
|
Takeguchi N et al. |
Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants FK506 and cyclosporine. |
1993 |
Transplantation |
pmid:7681229
|
Dutz JP et al. |
A role for calcineurin in degranulation of murine cytotoxic T lymphocytes. |
1993 |
J. Immunol. |
pmid:7681074
|
Saeki T et al. |
Human P-glycoprotein transports cyclosporin A and FK506. |
1993 |
J. Biol. Chem. |
pmid:7681059
|
Ning YM and Sánchez ER |
Potentiation of glucocorticoid receptor-mediated gene expression by the immunophilin ligands FK506 and rapamycin. |
1993 |
J. Biol. Chem. |
pmid:7681058
|
Piekoszewski W and Jusko WJ |
Plasma protein binding of tacrolimus in humans. |
1993 |
J Pharm Sci |
pmid:7680714
|
Nelson PA et al. |
Immunosuppressive activity of [MeBm2t]1-, D-diaminobutyryl-8-, and D-diaminopropyl-8-cyclosporin analogues correlates with inhibition of calcineurin phosphatase activity. |
1993 |
J. Immunol. |
pmid:7680683
|
Lionetti P et al. |
Activation of mucosal V beta 3+ T cells and tissue damage in human small intestine by the bacterial superantigen, Staphylococcus aureus enterotoxin B. |
1993 |
Eur. J. Immunol. |
pmid:7680613
|
Egan DA et al. |
Equilibrium denaturation of recombinant human FK binding protein in urea. |
1993 |
Biochemistry |
pmid:7680574
|
Xu RX et al. |
Heteronuclear 3D NMR studies of water bound to an FK506 binding protein/immunosuppressant complex. |
1993 |
Biochemistry |
pmid:7680570
|
Randhawa PS et al. |
The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine. |
1993 |
Am. J. Surg. Pathol. |
pmid:7680544
|
Armitage JM et al. |
A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7680396
|
Tamura K et al. |
Suppression of autoimmune thyroid disease by FK 506: influence on thyroid-infiltrating cells, adhesion molecule expression and anti-thyroglobulin antibody production. |
1993 |
Clin. Exp. Immunol. |
pmid:7680293
|
Hirao A et al. |
Effects of immunosuppressants, FK506, deoxyspergualin, and cyclosporine A on immature human hematopoiesis. |
1993 |
Blood |
pmid:7680241
|
Schweizer M et al. |
Sensitivity of mitochondrial peptidyl-prolyl cis-trans isomerase, pyridine nucleotide hydrolysis and Ca2+ release to cyclosporine A and related compounds. |
1993 |
Biochem. Pharmacol. |
pmid:7680201
|
Fukuzaki T et al. |
Induction of unresponsiveness to islet allograft by preoperative donor spleen cell injection and FK 506 treatment. |
1993 |
Transplant. Proc. |
pmid:7680173
|
Rilo HR et al. |
Effect of intraportal human islet transplantation on kidney graft survival in simultaneous kidney-islet allografts. |
1993 |
Transplant. Proc. |
pmid:7680172
|
Woan MC et al. |
Characterization of the biopsy growth assay in monitoring cardiac transplant patients for rejection. |
1993 |
Transplant. Proc. |
pmid:7680171
|
Mañez R et al. |
Association between donor-recipient HLA-DR compatibility and cytomegalovirus hepatitis and chronic rejection in liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7680170
|
McCauley J et al. |
FK 506 in the management of nephrotic syndrome after renal transplantation. |
1993 |
Transplant. Proc. |
pmid:7680154
|
Abu-Elmagd KM et al. |
Monitoring and treatment of intestinal allograft rejection in humans. |
1993 |
Transplant. Proc. |
pmid:7680150
|
Reyes J et al. |
Nutritional management of intestinal transplant recipients. |
1993 |
Transplant. Proc. |
pmid:7680149
|
Todo S et al. |
Intestinal transplantation in humans under FK 506. |
1993 |
Transplant. Proc. |
pmid:7680148
|
Shibata T et al. |
Does FK 506 accelerate the development of coronary artery disease in the transplanted heart as well as the native heart? |
1993 |
Transplant. Proc. |
pmid:7680147
|
Fung J et al. |
Randomized trial in primary liver transplantation under immunosuppression with FK 506 or cyclosporine. |
1993 |
Transplant. Proc. |
pmid:7680146
|
Bonet H et al. |
Survival of patients transplanted with alcoholic hepatitis plus cirrhosis as compared with those with cirrhosis alone. |
1993 |
Transplant. Proc. |
pmid:7680145
|
Stephens J et al. |
Effects of orthotopic liver transplantation and immunosuppression on inflammatory bowel disease in primary sclerosing cholangitis patients. |
1993 |
Transplant. Proc. |
pmid:7680144
|
Inoue T et al. |
Isolation of mitochondrial cyclophilin from bovine heart. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7679902
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive effects of purine and pyrimidine synthesis inhibitors. |
1993 |
Transplant. Proc. |
pmid:7679843
|
Gregory CR et al. |
Effects of treatment with cyclosporine, FK 506, rapamycin, mycophenolic acid, or deoxyspergualin on vascular muscle proliferation in vitro and in vivo. |
1993 |
Transplant. Proc. |
pmid:7679842
|
Gunji Y et al. |
Pathologic characteristics of vasculitis in renal transplant recipient dogs receiving immunosuppressive agents, FK 506, rapamycin, or RS-61443. |
1993 |
Transplant. Proc. |
pmid:7679841
|
Klintmalm GB et al. |
Use of Prograf (FK 506) as rescue therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group. |
1993 |
Transplant. Proc. |
pmid:7679840
|
Tabasco-Minguillan J et al. |
Long-term insulin requirement after liver transplantation with FK 506 in American veterans. |
1993 |
Transplant. Proc. |
pmid:7679839
|
Stock PG et al. |
Standard sequential immunosuppression with Minnesota antilymphoblast globulin and cyclosporine vs FK 506: a comparison of early nephrotoxicity. |
1993 |
Transplant. Proc. |
pmid:7679838
|