| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Postoperative Complications | D011183 | 5 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Neoplasm Recurrence, Local | D009364 | 5 associated lipids |
| Osteonecrosis | D010020 | 5 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Angioedema | D000799 | 6 associated lipids |
| Fractures, Spontaneous | D005598 | 4 associated lipids |
| Hydronephrosis | D006869 | 4 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Corneal Diseases | D003316 | 13 associated lipids |
| Testicular Diseases | D013733 | 15 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fellermann K et al. | Tacrolimus: a new immunosuppressant for steroid refractory inflammatory bowel disease. | 2001 | Transplant. Proc. | pmid:11377517 |
| Salizzoni M et al. | Tacrolimus-based dual therapy is as efficacious and safe as the conventional tacrolimus-based triple therapy in liver transplantation. | 2001 | Transplant. Proc. | pmid:11377521 |
| Langrehr JM et al. | Chronic rejection after orthotopic liver transplantation is increased under induction therapy with interleukin-2 receptor antibody BT563. | 2001 | Transplant. Proc. | pmid:11377531 |
| Migita K and Eguchi K | FK 506-mediated T-cell apoptosis induction. | 2001 | Transplant. Proc. | pmid:11377532 |
| Nakache R et al. | Management of massive proteinuria following renal transplantation with mycophenolate mofetil and blood pressure normalization. | 2001 | Transplant. Proc. | pmid:11377533 |
| Nakatani T et al. | Effect of tacrolimus on the gene expression of renin and endothelin in the rat kidney. | 2001 | Transplant. Proc. | pmid:11377534 |
| Schweizer RT and Meisterling LD | Tolerability of mycophenolate mofetil in organ transplant recipients. | 2001 | Transplant. Proc. | pmid:11377540 |
| Langrehr JM et al. | Quadruple versus dual tacrolimus-based induction after liver transplantation: a prospective, randomized trial. | 2001 | Transplant. Proc. | pmid:11377549 |
| Nagashima N et al. | Immunocompetence assay for net effect of combined immunosuppression. | 2001 | Transplant. Proc. | pmid:11377556 |
| Chariat MN et al. | Basiliximab in the therapy of acute rejection after organ transplantation. | 2001 | Transplant. Proc. | pmid:11377567 |
| Molinaro M et al. | Pharmacokinetics of tacrolimus during the early phase after heart transplantation. | 2001 | Transplant. Proc. | pmid:11377570 |
| McCarter JF et al. | FK 506 protects brain tissue in animal models of stroke. | 2001 | Transplant. Proc. | pmid:11377571 |
| van Gelder T et al. | ATP-binding cassette transporters and calcineurin inhibitors: potential clinical implications. | 2001 | Transplant. Proc. | pmid:11377580 |
| Sandborn WJ | Transcending conventional therapies: the role of biologic and other novel therapies. | 2001 | Inflamm. Bowel Dis. | pmid:11380043 |
| Teixeira R et al. | Management of recurrent hepatitis C after liver transplantation. | 2001 | J. Viral Hepat. | pmid:11380792 |
| Kooman JP et al. | A comparison between office and ambulatory blood pressure measurements in renal transplant patients with chronic transplant nephropathy. | 2001 | Am. J. Kidney Dis. | pmid:11382685 |
| Barten MJ et al. | Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro. | 2001 | J. Immunol. Methods | pmid:11384672 |
| Wakugawa M et al. | Interferon-gamma-induced RANTES production by human keratinocytes is enhanced by IL-1beta, TNF-alpha, IL-4 and IL-13 and is inhibited by dexamethasone and tacrolimus. | 2001 | Dermatology (Basel) | pmid:11385231 |
| Goffin E et al. | Osteoporosis after organ transplantation. | 2001 | Lancet | pmid:11386322 |
| Boillot O et al. | Low rejection rates with tacrolimus-based dual and triple regimens following liver transplantation. | 2001 | Clin Transplant | pmid:11389705 |
| Utsugi R et al. | Induction of transplantation tolerance with a short course of tacrolimus (FK506): I. Rapid and stable tolerance to two-haplotype fully mhc-mismatched kidney allografts in miniature swine. | 2001 | Transplantation | pmid:11391221 |
| Yin DP et al. | Lewis rat pancreas, but not cardiac xenografts, are resistant to anti-gal antibody mediated hyperacute rejection. | 2001 | Transplantation | pmid:11391223 |
| Karasu Z et al. | Acute tacrolimus overdose and treatment with phenytoin in liver transplant recipients. | 2001 | J Okla State Med Assoc | pmid:11392178 |
| Maesaki S | [Molecular mechanize and clinical feature of azole-resistant Candida albicans strains and new strategy of treatment]. | 2001 | Jpn J Antibiot | pmid:11392683 |
| Tuteja S et al. | The effect of gut metabolism on tacrolimus bioavailability in renal transplant recipients. | 2001 | Transplantation | pmid:11397967 |
| Otsuka M et al. | Long-term results of donor-specific blood transfusion with cyclosporine in living related kidney transplantation. | 2001 | Nephron | pmid:11399917 |
| Bekersky I et al. | Comparative tacrolimus pharmacokinetics: normal versus mildly hepatically impaired subjects. | 2001 | J Clin Pharmacol | pmid:11402631 |
| Penson MG et al. | Safety and efficacy of pravastatin therapy for the prevention of hyperlipidemia in pediatric and adolescent cardiac transplant recipients. | 2001 | J. Heart Lung Transplant. | pmid:11404165 |
| Allen A et al. | Significant absorption of topical tacrolimus in 3 patients with Netherton syndrome. | 2001 | Arch Dermatol | pmid:11405764 |
| Diaz-Romero J et al. | Coexpression of CD4 and CD8alpha on rat T-cells in whole blood: a sensitive marker for monitoring T-cell immunosuppressive drugs. | 2001 | J. Immunol. Methods | pmid:11406149 |
| Osako M et al. | Alloimmune response may be involved in neointimal hyperplasia in cryopreserved aortic allografts. | 2001 | Transplant. Proc. | pmid:11406250 |
| Faivre L et al. | FK 506 dose in transplantation: from theory to practice. | 2001 | Transplant. Proc. | pmid:11406256 |
| Chan KL et al. | Porcine small bowel transplantation with FK506 as a single immunosuppressant. | 2001 | Transplant. Proc. | pmid:11406260 |
| Charpentier B | An induction versus no-induction protocol in anticalcineurin-based immunosuppression using very low-dose steroids. | 2001 | Transplant. Proc. | pmid:11406262 |
| Weir MR | Methods and outcomes of calcineurin inhibitor reduction or withdrawal in patients with chronic allograft nephropathy after the first year posttransplantation. | 2001 | Transplant. Proc. | pmid:11406264 |
| Land W et al. | Mycophenolate mofetil monotherapy: an optimal, safe, and efficacious immunosuppressive maintenance regimen in kidney transplant patients. | 2001 | Transplant. Proc. | pmid:11406265 |
| Sakuma S et al. | Tacrolimus suppressed the production of cytokines involved in atopic dermatitis by direct stimulation of human PBMC system. (Comparison with steroids). | 2001 | Int. Immunopharmacol. | pmid:11407316 |
| Shimoishi K et al. | FK506 (tacrolimus) increases rat alpha1-acid glycoprotein expression in liver and primary cultured hepatocytes. | 2001 | Eur. J. Pharmacol. | pmid:11408029 |
| Navarro X et al. | Effects of FK506 on nerve regeneration and reinnervation after graft or tube repair of long nerve gaps. | 2001 | Muscle Nerve | pmid:11410918 |
| Hiroi J | [Pharmacological profile and clinical effect of tacrolimus ointment (Protopic ointment) for atopic dermatitis]. | 2001 | Nippon Yakurigaku Zasshi | pmid:11411345 |
| Kaibori M et al. | FK506, but not cyclosporin A, prevents mitochondrial dysfunction during hypoxia in rat hepatocytes. | 2001 | Life Sci. | pmid:11411802 |
| Sun J et al. | Role for p27(Kip1) in Vascular Smooth Muscle Cell Migration. | 2001 | Circulation | pmid:11413088 |
| Sing A et al. | Molecular diagnosis of an Enterocytozoon bieneusi human genotype C infection in a moderately immunosuppressed human immunodeficiency virus seronegative liver-transplant recipient with severe chronic diarrhea. | 2001 | J. Clin. Microbiol. | pmid:11414246 |
| Kolpak S and Mehler P | Medical issues in treating renal transplant patients. | 2001 | Hosp Pract (1995) | pmid:11419536 |
| Chang RK et al. | Echocardiographic findings of hypertrophic cardiomyopathy in children after orthotopic liver transplantation. | 2001 | Pediatr Transplant | pmid:11422821 |
| Hasegawa T et al. | Oral administration of tacrolimus in the presence of jejunostomy after liver transplantation. | 2001 | Pediatr Transplant | pmid:11422824 |
| Kanoh S et al. | FK506 inhibits Cl- secretion in airway epithelium via calcineurin-independent mechanism. | 2001 | Eur. J. Pharmacol. | pmid:11426833 |
| Mourad M et al. | Pharmacokinetic basis for the efficient and safe use of low-dose mycophenolate mofetil in combination with tacrolimus in kidney transplantation. | 2001 | Clin. Chem. | pmid:11427455 |
| Matsuo N et al. | Tacrolimus inhibits cytokine production and chemical mediator release following antigen stimulation of passively sensitized human lung tissues. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11428741 |
| Ramm K and Plückthun A | High enzymatic activity and chaperone function are mechanistically related features of the dimeric E. coli peptidyl-prolyl-isomerase FkpA. | 2001 | J. Mol. Biol. | pmid:11428902 |