tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Drake M et al. | The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain. | 1996 | Acta Physiol. Scand. | pmid:8899062 |
| Ibarra FR et al. | Intracellular sodium modulates the state of protein kinase C phosphorylation of rat proximal tubule Na+,K+-ATPase. | 2002 | Acta Physiol. Scand. | pmid:12028137 |
| Folwarczna J et al. | Effect of low-dose tacrolimus coadministered with raloxifene on the skeletal system in male rats. | 2009 Mar-Apr | Acta Pol Pharm | pmid:19719057 |
| Turło J et al. | Submerged cultivation of Streptomyces tsukubaensis in media composed of waste products of food industry. | 2006 Sep-Oct | Acta Pol Pharm | pmid:17357618 |
| Kaczmarczyk-Sedlak I et al. | Raloxifene does not affect the changes in bone histomorphometric parameters induced by low dose tacrolimus in male rats. | 2006 Jul-Aug | Acta Pol Pharm | pmid:17203868 |
| Wartenberg KE et al. | Transient diffusion-weighted imaging changes in a patient with reversible leukoencephalopathy syndrome. | 2004 | Acta Radiol | pmid:15587428 |
| Radziejewski K et al. | Assessment of corneal and conjunctival metaplasia by impression cytology during the treatment of canine keratoconjunctivitis sicca. | 2018 | Acta Vet. Hung. | pmid:29958527 |
| Radziejewski K and Balicki I | Comparative clinical evaluation of tacrolimus and cyclosporine eye drops for the treatment of canine keratoconjunctivitis sicca. | 2016 | Acta Vet. Hung. | pmid:27653428 |
| Kageyama S et al. | Augmentation of natural killer cell activity induced by cytomegalovirus infection in mice treated with FK506. | 1997 | Acta Virol. | pmid:9391652 |
| Ormaechea-Pérez N et al. | Superficial granulomatous pyoderma. Report of 2 cases treated with topical tacrolimus. | 2013 | Actas Dermosifiliogr | pmid:23933249 |
| Varela-Veiga A et al. | Long-standing Papules on the Scrotum. | 2017 | Actas Dermosifiliogr | pmid:27328825 |
| Alomar A | [Role of topical calcineurin inhibitors in dermatology]. | 2008 | Actas Dermosifiliogr | pmid:18346422 |
| Undre NA | [Pharmacokinetics of tacrolimus following topical application of tacrolimus ointment in adult and paediatric patients with atopic dermatitis]. | 2008 | Actas Dermosifiliogr | pmid:18346423 |
| Ortiz de Frutos FJ | [Atopic dermatitis and tacrolimus in adults]. | 2008 | Actas Dermosifiliogr | pmid:18346424 |
| Torrelo A | [Topical tacrolimus in atopic dermatitis in children]. | 2008 | Actas Dermosifiliogr | pmid:18346425 |
| Sánchez-Pérez J | [Safety information for tacrolimus: present and future]. | 2008 | Actas Dermosifiliogr | pmid:18346426 |
| Alomar A et al. | [Tacrolimus in diseases other than atopic dermatitis]. | 2008 | Actas Dermosifiliogr | pmid:18346427 |
| GarcÃa-Delgado R et al. | Systemic Absorption of Topical Tacrolimus in Metastatic Crohn Disease With Skin Ulcers. | 2016 | Actas Dermosifiliogr | pmid:27372545 |
| Sánchez-Pérez J | [Topical pimecrolimus and tacrolimus and the risk of cancer]. | 2007 | Actas Dermosifiliogr | pmid:17555673 |
| Apalla Z et al. | Psoriatic cheilitis: a report of 2 cases treated successfully with topical tacrolimus and a review of the literature. | 2015 | Actas Dermosifiliogr | pmid:26164836 |