tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Summaries for patients. Multitarget therapy for induction treatment of lupus nephritis. | 2015 | Ann. Intern. Med. | pmid:25383607 | |
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| Carenco C et al. | Incidence of solid organ cancers after liver transplantation: comparison with regional cancer incidence rates and risk factors. | 2015 | Liver Int. | pmid:25488375 |
| Yano S et al. | Pharmacokinetics for once-daily modified release formulation of tacrolimus hydrate in unrelated hematopoietic stem cell transplantation. | 2015 | Ann. Hematol. | pmid:25325985 |
| Garcia C et al. | Collaborative Brazilian Pediatric Renal Transplant Registry (CoBrazPed-RTx): A Report From 2004 to 2013. | 2015 | Transplant. Proc. | pmid:26036492 |
| Melo MJ et al. | Impact of conversion from Advagraf to twice-daily generic tacrolimus in kidney transplant recipients: a single-center study. | 2015 | Transplant. Proc. | pmid:26036484 |
| Santos T et al. | New Recipes With Known Ingredients: Combined Therapy of Everolimus and Low-dose Tacrolimus in De Novo Renal Allograft Recipients. | 2015 | Transplant. Proc. | pmid:26036483 |
| Liu Z et al. | Multitarget therapy for induction treatment of lupus nephritis: a randomized trial. | 2015 | Ann. Intern. Med. | pmid:25383558 |
| Bifano M et al. | An open-label investigation into drug-drug interactions between multiple doses of daclatasvir and single-dose cyclosporine or tacrolimus in healthy subjects. | 2015 | Clin Drug Investig | pmid:25896946 |
| Caro J et al. | Predictors of response and relapse in patients with idiopathic membranous nephropathy treated with tacrolimus. | 2015 | Nephrol. Dial. Transplant. | pmid:25274748 |
| Wang L et al. | Benefits of minimizing immunosuppressive dosage according to cytochrome P450 3A5 genotype in liver transplant patients: findings from a single-center study. | 2015 | Genet. Mol. Res. | pmid:25966085 |
| Colak H et al. | Relationship of Interleukin-10 and Transforming Growth Factor-β Levels With Short-Term Graft Function After Kidney Transplantation. | 2015 | Transplant. Proc. | pmid:25964218 |
| Kim YT et al. | Co-treatment effect of pulsed electromagnetic field (PEMF) with human dental pulp stromal cells and FK506 on the regeneration of crush injured rat sciatic nerve. | 2015 | Int. J. Neurosci. | pmid:25271799 |
| Kogiso T et al. | Mycophenolate mofetil may induce prolonged severe anemia during pegylated-interferon/ribavirin/simeprevir therapy in liver transplant recipients. | 2015 | Clin J Gastroenterol | pmid:25963122 |
| Tabchi S et al. | Successful treatment of Evans syndrome with Tacrolimus. | 2015 | Invest New Drugs | pmid:25209619 |
| Papadopoulos-Köhn A et al. | Daily low-dose tacrolimus is a safe and effective immunosuppressive regimen during telaprevir-based triple therapy for hepatitis C virus recurrence after liver transplant. | 2015 | Transplantation | pmid:25208324 |
| Bae JM et al. | Combination therapy with 308-nm excimer laser, topical tacrolimus, and short-term systemic corticosteroids for segmental vitiligo: A retrospective study of 159 patients. | 2015 | J. Am. Acad. Dermatol. | pmid:25956660 |
| Weisenseel P and Reich K | [Inverse psoriasis]. | 2015 | Hautarzt | pmid:25896586 |
| Ennaifer R et al. | Nodular hyperplasia of the gastrointestinal tract after liver transplantation: role of immunosuppressive therapy? A case report. | 2015 | Transplant. Proc. | pmid:25891739 |
| Chen KH et al. | De novo cancer avoidance after renal transplantation: A case-control study on low-dose sirolimus combined with a calcineurin inhibitor. | 2015 | J. Formos. Med. Assoc. | pmid:25843527 |
| Berro M et al. | Allogeneic hematopoietic stem cell transplantation in the elderly. Predicting the risk for non relapse mortality. | 2015 | Medicina (B Aires) | pmid:26339873 |
| Robertsen I et al. | Use of generic tacrolimus in elderly renal transplant recipients: precaution is needed. | 2015 | Transplantation | pmid:25148382 |
| Wang L et al. | Gq signaling causes glomerular injury by activating TRPC6. | 2015 | J. Clin. Invest. | pmid:25844902 |
| Legendre L et al. | Risk of lymphoma in patients with atopic dermatitis and the role of topical treatment: A systematic review and meta-analysis. | 2015 | J. Am. Acad. Dermatol. | pmid:25840730 |
| Manuyakorn W et al. | In vitro cytokine changes after pediatric liver transplantation. | 2015 | Asian Pac. J. Allergy Immunol. | pmid:25840634 |
| Aouam K et al. | Influence of combined CYP3A4 and CYP3A5 single-nucleotide polymorphisms on tacrolimus exposure in kidney transplant recipients: a study according to the post-transplant phase. | 2015 | Pharmacogenomics | pmid:26615671 |
| Eaton KV et al. | Engineering macrophages to control the inflammatory response and angiogenesis. | 2015 | Exp. Cell Res. | pmid:26610863 |
| Tavira B et al. | ABCB1 (MDR-1) pharmacogenetics of tacrolimus in renal transplanted patients: a Next Generation Sequencing approach. | 2015 | Clin. Chem. Lab. Med. | pmid:25781547 |
| Burke MT et al. | Expression of Bcl-xL and Mcl-1 in the nonmelanoma skin cancers of renal transplant recipients. | 2015 | Am. J. Clin. Pathol. | pmid:25780003 |
| Plischke M et al. | Late Conversion of Kidney Transplant Recipients from Ciclosporin to Tacrolimus Improves Graft Function: Results from a Randomized Controlled Trial. | 2015 | PLoS ONE | pmid:26270340 |
| Nouchi A et al. | [Treatment of angiolymphoid hyperplasia with eosinophilia (ALHE) using topical tacrolimus: Two cases]. | 2015 | Ann Dermatol Venereol | pmid:25778634 |
| Chen F et al. | [Outcomes of allogeneic hematopoietic stem cell transplantation for 18 patients with paroxysmal nocturnal haemoglobinuria]. | 2015 | Zhonghua Xue Ye Xue Za Zhi | pmid:26759101 |
| Morales E et al. | A case of thrombotic micro-angiopathy after heart transplantation successfully treated with eculizumab. | 2015 | Transpl. Int. | pmid:25712140 |
| Buschow SI et al. | To target or not to target viral antigens in HBV related HCC? | 2015 | J. Hepatol. | pmid:25711422 |
| Qasim W et al. | Reply to: "To target or not to target viral antigens in HBV related HCC?". | 2015 | J. Hepatol. | pmid:25711420 |
| Jia N et al. | Collapsing focal segmental glomerulosclerosis following long-term treatment with oral ibandronate: case report and review of literature. | 2015 | BMC Cancer | pmid:26197890 |
| Kawano N et al. | Successful Secondary Umbilical Cord Blood Transplantation for Graft Failure in Acute Myelogenous Leukemia, Treated with Modified One-Day Conditioning Regimen, and Graft-Versus-Host Disease Prophylaxis Consisting of Mycophenolate and Tacrolimus. | 2015 | J Clin Exp Hematop | pmid:26490521 |
| Li ZQ et al. | Efficacy and safety of tacrolimus vs. cyclophosphamide for idiopathic membranous nephropathy: A meta-analysis of Chinese adults. | 2015 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26489612 |
| Badri P et al. | Pharmacokinetics and dose recommendations for cyclosporine and tacrolimus when coadministered with ABT-450, ombitasvir, and dasabuvir. | 2015 | Am. J. Transplant. | pmid:25708713 |
| Ayala E et al. | Myeloablative intravenous pharmacokinetically targeted busulfan plus fludarabine as conditioning for allogeneic hematopoietic cell transplantation in patients with non-Hodgkin lymphoma. | 2015 | Clin Lymphoma Myeloma Leuk | pmid:25659459 |
| Stefanović NZ et al. | Potential role of tacrolimus in erythrocytes' antioxidative capacity in long-term period after renal transplantation. | 2015 | Eur J Pharm Sci | pmid:25657088 |
| Park JH et al. | Comparative study of tacrolimus and bevacizumab on corneal neovascularization in rabbits. | 2015 | Cornea | pmid:25651492 |
| Petruzzo P et al. | Outcomes after bilateral hand allotransplantation: a risk/benefit ratio analysis. | 2015 | Ann. Surg. | pmid:24646555 |
| Polańska A et al. | Monitoring of therapy in atopic dermatitis--observations with the use of high-frequency ultrasonography. | 2015 | Skin Res Technol | pmid:24894324 |
| Sahin G et al. | Association between endothelial and platelet function markers and adiponectin in renal transplanted recipients on cyclosporine and tacrolimus immunosuppression based therapy. | 2015 | Nephrology (Carlton) | pmid:25650527 |
| Pérez-López I et al. | Koebner phenomenon in a patient with lichen sclerosus following a jellyfish sting: an exceptional morphology. | 2015 | Actas Dermosifiliogr | pmid:25597413 |
| Niioka T et al. | Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation. | 2015 | Int J Mol Sci | pmid:25594874 |
| Rojas-Vega L et al. | Increased phosphorylation of the renal Na+-Cl- cotransporter in male kidney transplant recipient patients with hypertension: a prospective cohort. | 2015 | Am. J. Physiol. Renal Physiol. | pmid:26336164 |
| Ling Q et al. | Donor PPARα Gene Polymorphisms Influence the Susceptibility to Glucose and Lipid Disorders in Liver Transplant Recipients: A Strobe-Compliant Observational Study. | 2015 | Medicine (Baltimore) | pmid:26334901 |
| Koch M et al. | De novo mTOR inhibitor-based immunosuppression in ABO-incompatible kidney transplantation. | 2015 | Clin Transplant | pmid:26333844 |
| Graham F et al. | Tacrolimus use in renal and cardiac pediatric transplantation: no increased risk of food allergies. | 2015 | Ann. Allergy Asthma Immunol. | pmid:26094803 |
| Teixeira Mdo C et al. | Influence of post-transplant immunosuppressive therapy on gastrointestinal transit using biomagnetic method: a pilot study. | 2015 | Dig. Dis. Sci. | pmid:25146844 |
| Urquhart BL and Knauer MJ | Dried blood spots for therapeutic drug monitoring of tacrolimus and sirolimus in pediatric patients. | 2015 | Pediatr Transplant | pmid:25546506 |
| Park J et al. | Iron overload triggers mitochondrial fragmentation via calcineurin-sensitive signals in HT-22 hippocampal neuron cells. | 2015 | Toxicology | pmid:26318285 |
| Shi RZ et al. | Rapid measurement of tacrolimus in whole blood by paper spray-tandem mass spectrometry (PS-MS/MS). | 2015 | Clin. Chim. Acta | pmid:25540885 |
| Coilly A et al. | Once-daily prolonged release tacrolimus in liver transplantation: Experts' literature review and recommendations. | 2015 | Liver Transpl. | pmid:26264233 |
| Boluda ER | Pediatric small bowel transplantation. | 2015 | Curr Opin Organ Transplant | pmid:26262456 |
| Minami-Hori M et al. | Periorbital lupus profundus successfully treated with oral tacrolimus plus low-dose prednisolone. | 2015 | J. Dermatol. | pmid:25544984 |
| Xing J et al. | Association between interleukin-18 promoter variants and tacrolimus pharmacokinetics in Chinese renal transplant patients. | 2015 | Eur. J. Clin. Pharmacol. | pmid:25487141 |
| van Boekel GA et al. | Delayed trough level measurement with the use of prolonged-release tacrolimus. | 2015 | Transpl. Int. | pmid:25474192 |
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| Gallagher HM et al. | Erratic tacrolimus exposure, assessed using the standard deviation of trough blood levels, predicts chronic lung allograft dysfunction and survival. | 2015 | J. Heart Lung Transplant. | pmid:26186804 |
| Li Y et al. | Differential regulation of Tregs and Th17/Th1 cells by a sirolimus-based regimen might be dependent on STAT-signaling in renal transplant recipients. | 2015 | Int. Immunopharmacol. | pmid:26186486 |
| Toole B et al. | Evaluation of the New Cyclosporine and Tacrolimus Automated Electrochemiluminescence Immunoassays under Field Conditions. | 2015 | Clin. Lab. | pmid:26554251 |
| Shen T et al. | Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. | 2015 | World J. Gastroenterol. | pmid:26034381 |
| Cilião HL et al. | Cytotoxic and genotoxic effects of high concentrations of the immunosuppressive drugs cyclosporine and tacrolimus in MRC-5 cells. | 2015 | Exp. Toxicol. Pathol. | pmid:25541063 |
| Kabrine M and Laraba-Djebari F | Immunomodulatory and protective properties of tacrolimus in experimental scorpion envenomation. | 2014 Jan-Mar | Int J Immunopathol Pharmacol | pmid:24674680 |
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| Kabir A | Comment on: New-onset diabetes and impaired fasting glucose after a liver transplant: risk analysis and the effect of tacrolimus dosage. | 2014 | Exp Clin Transplant | pmid:24471727 |
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| Capone F et al. | Synergistic antitumor effect of Doxorubicin and tacrolimus (FK506) on hepatocellular carcinoma cell lines. | 2014 | ScientificWorldJournal | pmid:24701168 |
| Tischer S and Fontana RJ | Drug-drug interactions with oral anti-HCV agents and idiosyncratic hepatotoxicity in the liver transplant setting. | 2014 | J. Hepatol. | pmid:24280292 |
| Arduino PG et al. | Pimecrolimus vs. tacrolimus for the topical treatment of unresponsive oral erosive lichen planus: a 8 week randomized double-blind controlled study. | 2014 | J Eur Acad Dermatol Venereol | pmid:23451852 |
| Wasilewski G et al. | Inadequate blood pressure control in orthotopic heart transplant: is there a role of kidney function and immunosuppressive regimen? | 2014 | Transplant. Proc. | pmid:25380929 |
| Grafals M et al. | Immunophenotyping and efficacy of low dose ATG in non-sensitized kidney recipients undergoing early steroid withdrawal: a randomized pilot study. | 2014 | PLoS ONE | pmid:25111080 |
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| Bica L et al. | Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation. | 2014 | PLoS ONE | pmid:24587210 |
| Bergmann TK et al. | Population pharmacokinetics of tacrolimus in adult kidney transplant patients: impact of CYP3A5 genotype on starting dose. | 2014 | Ther Drug Monit | pmid:24089074 |
| Aelvoet SA et al. | Noninvasive bioluminescence imaging of α-synuclein oligomerization in mouse brain using split firefly luciferase reporters. | 2014 | J. Neurosci. | pmid:25471588 |
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| Ikeuchi H et al. | Efficacy and safety of multi-target therapy using a combination of tacrolimus, mycophenolate mofetil and a steroid in patients with active lupus nephritis. | 2014 | Mod Rheumatol | pmid:24252014 |
| Zhao J et al. | FK506-loaded chitosan conduit promotes the regeneration of injured sciatic nerves in the rat through the upregulation of brain-derived neurotrophic factor and TrkB. | 2014 | J. Neurol. Sci. | pmid:24954089 |
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| Hacker C et al. | Falsely elevated cyclosporin and tacrolimus concentrations over prolonged periods of time due to reversible adsorption to central venous catheters. | 2014 | Clin. Chim. Acta | pmid:24631133 |
| Hallowell RW and Danoff SK | Interstitial lung disease associated with the idiopathic inflammatory myopathies and the antisynthetase syndrome: recent advances. | 2014 | Curr Opin Rheumatol | pmid:25203119 |
| Lalan S et al. | Effect of CYP3A5 genotype, steroids, and azoles on tacrolimus in a pediatric renal transplant population. | 2014 | Pediatr. Nephrol. | pmid:24875272 |
| Ricardo E et al. | In vivo and in vitro acquisition of resistance to voriconazole by Candida krusei. | 2014 | Antimicrob. Agents Chemother. | pmid:24867987 |
| Agrawal YP et al. | Transplant patient classification and tacrolimus assays: more evidence of the need for assay standardization. | 2014 | Ther Drug Monit | pmid:24784024 |
| Mitsides N et al. | Dapsone-induced methemoglobinemia in renal transplant recipients: more prevalent than previously thought. | 2014 | Transpl Infect Dis | pmid:24215452 |
| Nair S and Waters B | Telaprevir in treatment of recurrent hepatitis C infection in liver transplant recipients. | 2014 | Exp Clin Transplant | pmid:24702143 |
| Navas-López VM et al. | Successful treatment for ulcerative proctitis with rectal tacrolimus in an 8-year-old girl with intolerance to mesalamine. | 2014 | Clin J Gastroenterol | pmid:26185880 |