Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Schlosser K et al. | Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters! | 2007 | World J Surg | pmid:17665243 |
Platz KP et al. | Management of acute steroid-resistant rejection after liver transplantation. | 1996 | World J Surg | pmid:8798364 |
Sutherland DE et al. | Pancreas transplantation for treatment of diabetes mellitus. | 2001 | World J Surg | pmid:11344403 |
Kato T et al. | Intestinal and multivisceral transplantation. | 2002 | World J Surg | pmid:11865353 |
Ramakant P and Agarwal G | Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters: surgical management of tertiary hyperparathyroidism: an enigma. | 2008 | World J Surg | pmid:18404286 |
Zong YP et al. | Effects of CYP3A5 polymorphisms on tacrolimus pharmacokinetics in pediatric kidney transplantation: a systematic review and meta-analysis of observational studies. | 2017 | World J Pediatr | pmid:28540692 |
Yang EM et al. | Tacrolimus for children with refractory nephrotic syndrome: a one-year prospective, multicenter, and open-label study of Tacrobell®, a generic formula. | 2016 | World J Pediatr | pmid:26684309 |
Kallash M and Aviles D | Efficacy of tacrolimus in the treatment of children with focal segmental glomerulosclerosis. | 2014 | World J Pediatr | pmid:24801235 |
Sperr WR et al. | [Effector cells in allergy: biological principles and new pharmacologic concepts]. | 1993 | Wien. Klin. Wochenschr. | pmid:7508662 |
Haas M et al. | Hypothyroidism as a cause of tacrolimus intoxication and acute renal failure: a case report. | 2000 | Wien. Klin. Wochenschr. | pmid:11144010 |