tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yang A and Wang B | Sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids: focus on acute rejection, patient and graft survival. | Am J Ther | pmid:23921809 | |
| Pariser D | Topical corticosteroids and topical calcineurin inhibitors in the treatment of atopic dermatitis: focus on percutaneous absorption. | 2009 May-Jun | Am J Ther | pmid:19262357 |
| Azizian M et al. | Augmentation of ischemia/reperfusion injury to endothelial cells by cyclosporin A. | 2004 | Am Surg | pmid:15156953 |
| Henderson CN et al. | Continuous Abdominal Irrigation for Treatment of Tertiary Peritonitis in the Immunosuppressed Patient after Solid Organ Transplant: A Novel Approach. | 2017 | Am Surg | pmid:28424115 |
| Rojas-GarcÃa P et al. | Breast fibroadenomas associated with immunosuppressive drugs. | 2010 | Am Surg | pmid:21418766 |
| Kodama M et al. | FK506 therapy of experimental autoimmune myocarditis after onset of the disease. | 1993 | Am. Heart J. | pmid:7504393 |
| Chieffo A et al. | Histopathology of clinical coronary restenosis in drug-eluting versus bare metal stents. | 2009 | Am. J. Cardiol. | pmid:19962471 |
| Chang RK et al. | Marked left ventricular hypertrophy in children on tacrolimus (FK506) after orthotopic liver transplantation. | 1998 | Am. J. Cardiol. | pmid:9604971 |
| Klauss V et al. | Cyclosporine versus tacrolimus (FK 506) for prevention of cardiac allograft vasculopathy. | 2000 | Am. J. Cardiol. | pmid:10955391 |
| Herzberg GZ et al. | Usefulness of tacrolimus versus cyclosporine after pediatric heart transplantation. | 1998 | Am. J. Cardiol. | pmid:9723652 |
| Hisamura F et al. | Synergistic effect of green tea polyphenols on their protection against FK506-induced cytotoxicity in renal cells. | 2008 | Am. J. Chin. Med. | pmid:18543393 |
| Chung SY et al. | Ginkgo biloba leaf extract (EGb761) combined with neuroprotective agents reduces the infarct volumes of gerbil ischemic brain. | 2006 | Am. J. Chin. Med. | pmid:17080546 |
| Stickle DF et al. | Effects of sterilizing gamma irradiation on bloodspot newborn screening tests and whole blood cyclosporine and tacrolimus measurements. | 2003 | Am. J. Clin. Pathol. | pmid:12580001 |
| Wang E et al. | Pseudo-Pelger-Huët anomaly induced by medications: a clinicopathologic study in comparison with myelodysplastic syndrome-related pseudo-Pelger-Huët anomaly. | 2011 | Am. J. Clin. Pathol. | pmid:21228370 |
| Burke MT et al. | Expression of Bcl-xL and Mcl-1 in the nonmelanoma skin cancers of renal transplant recipients. | 2015 | Am. J. Clin. Pathol. | pmid:25780003 |
| Lower DR et al. | Comparison of CEDIA FK506 assay with HPLC/MS/MS in a large cohort of pediatric patients. | 2013 | Am. J. Clin. Pathol. | pmid:23690122 |
| Van Thiel DH et al. | Tacrolimus (FK 506), a treatment for primary sclerosing cholangitis: results of an open-label preliminary trial. | 1995 | Am. J. Gastroenterol. | pmid:7532912 |
| Baumgart DC et al. | Tacrolimus is safe and effective in patients with severe steroid-refractory or steroid-dependent inflammatory bowel disease--a long-term follow-up. | 2006 | Am. J. Gastroenterol. | pmid:16573777 |
| Sandborn WJ | Preliminary report on the use of oral tacrolimus (FK506) in the treatment of complicated proximal small bowel and fistulizing Crohn's disease. | 1997 | Am. J. Gastroenterol. | pmid:9149205 |
| Fellermann K et al. | Steroid-unresponsive acute attacks of inflammatory bowel disease: immunomodulation by tacrolimus (FK506). | 1998 | Am. J. Gastroenterol. | pmid:9772045 |