Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Deng Z et al. | [Early diagnosis and comprehensive treatments of post-transplantation lymphoproliferative disorder after pediatric liver transplantation]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25224233 |
Yao SH et al. | [Clinical application of tacrolimus with low-dose prednisone in 21 children with steroid-resistant nephrotic syndrome]. | 2011 | Zhonghua Er Ke Za Zhi | pmid:22336304 |
Zhang J et al. | [Effects of sirolimus on the growth of transplanted hepatocellular carcinoma]. | 2009 | Zhonghua Gan Zang Bing Za Zhi | pmid:19567017 |
Qian SK et al. | [The prevention and management of cerebrovascular complications in nine cases after orthotopic liver transplantation]. | 2005 | Zhonghua Gan Zang Bing Za Zhi | pmid:16313741 |
Sun YJ and Sun Z | [Treatment of erosive oral lichen planus with topical tacrolimus]. | 2010 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:20450689 |
Zhao S et al. | [Effects of tacrolimus (FK506) on heat-shock proteins 70, Bcl-2 and Bax expression in nervous tissue of acrylamide-induced rat]. | 2010 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | pmid:20465949 |
Sun L et al. | [Effect of FK506 on the cavernous nerve regeneration after injury]. | 2005 | Zhonghua Nan Ke Xue | pmid:15755036 |
Cao ZG et al. | [Effects of different immunodepressants on the sperm parameters of kidney transplant recipients]. | 2006 | Zhonghua Nan Ke Xue | pmid:16755867 |
Chen YP et al. | [The clinical efficacy and safety of tacrolimus in patients with myasthenia gravis]. | 2013 | Zhonghua Nei Ke Za Zhi | pmid:24266997 |
Li YX et al. | [Preliminary experience with Campath 1H induction combined with low-dose monotherapy of tacrolimus in small bowel transplantation]. | 2009 | Zhonghua Wai Ke Za Zhi | pmid:19961008 |