tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Pharmacol. Exp. Ther. (1)
- Am. J. Physiol. Renal Physiol. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tanaka Y et al. | Cooperation between ER stress and calcineurin signaling contributes to the maintenance of cell wall integrity in Candida glabrata. | 2018 | Fungal Biol | pmid:29248112 |
| Sikma MA et al. | Association of Whole Blood Tacrolimus Concentrations with Kidney Injury in Heart Transplantation Patients. | 2018 | Eur J Drug Metab Pharmacokinet | pmid:29236211 |
| Lamanna JJ et al. | Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord. | 2018 | J Clin Neurosci | pmid:29089163 |
| Kim JP et al. | The effect of full dose composite tissue allotransplantation immunosuppression on allograft motor nerve regeneration in a rat sciatic nerve model. | 2018 | Microsurgery | pmid:28792625 |
| Chandran SR et al. | A Model of Acute Antibody-Mediated Renal Allograft Rejection in the Sensitized Rata. | 2018 | Exp Clin Transplant | pmid:28760115 |
| Ordóñez-Robles M et al. | Genome-wide transcriptome response of Streptomyces tsukubaensis to N-acetylglucosamine: effect on tacrolimus biosynthesis. | 2018 | Microbiol. Res. | pmid:30384905 |
| Hamano I et al. | Condyloma Acuminata of the Urethra in a Male Renal Transplant Recipient: A Case Report. | 2018 | Transplant. Proc. | pmid:30316397 |
| Choong CL et al. | Dose-Response Relationship Between Diltiazem and Tacrolimus and Its Safety in Renal Transplant Recipients. | 2018 | Transplant. Proc. | pmid:30316389 |
| Tunnicliffe DJ et al. | Immunosuppressive treatment for proliferative lupus nephritis. | 2018 | Cochrane Database Syst Rev | pmid:29957821 |
| Del Bello A et al. | High tacrolimus intra-patient variability is associated with graft rejection, and donor-specific antibodies occurrence after liver transplantation. | 2018 | World J. Gastroenterol. | pmid:29713132 |
| Lin G et al. | Evaluation of tacrolimus-related CYP3A5 genotyping in China: Results from the First External Quality Assessment Exercise. | 2018 | J. Clin. Lab. Anal. | pmid:29708622 |
| Luaces-RodrÃguez A et al. | Preclinical characterization and clinical evaluation of tacrolimus eye drops. | 2018 | Eur J Pharm Sci | pmid:29705214 |
| Hong D et al. | [Atopic keratoconjunctivitis: One allergy may mask another. A clinical observation with two types of hypersensitivity reactions: IgE-mediated and non-IgE-mediated]. | 2018 | J Fr Ophtalmol | pmid:29567021 |
| Ekici Günay N et al. | Administration of Extract (EGb761) Alone and in Combination with FK506 Promotes Liver Regeneration in a Rat Model of Partial Hepatectomy. | 2018 | Balkan Med J | pmid:29553465 |
| Zhang X et al. | Current progress of tacrolimus dosing in solid organ transplant recipients: Pharmacogenetic considerations. | 2018 | Biomed. Pharmacother. | pmid:29550633 |
| Chen X et al. | A case report of lupus erythematosus tumidus converted from discoid lupus erythematosus. | 2018 | Medicine (Baltimore) | pmid:29668590 |
| Li A et al. | Atopic keratoconjunctivitis: A diagnostic dilemma-a case report. | 2018 | Medicine (Baltimore) | pmid:29668589 |
| Onodera M et al. | Tacrolimus Dose Optimization Strategy for Refractory Ulcerative Colitis Based on the Cytochrome P450 3A5 Polymorphism Prediction Using Trough Concentration after 24 Hours. | 2018 | Digestion | pmid:29393157 |
| Liu YC et al. | A Biodegradable, Sustained-Released, Tacrolimus Microfilm Drug Delivery System for the Management of Allergic Conjunctivitis in a Mouse Model. | 2018 | Invest. Ophthalmol. Vis. Sci. | pmid:29392313 |
| Yu M et al. | Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation. | 2018 | Curr. Drug Metab. | pmid:29380698 |