tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Fibroadenoma D018226 2 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Flaviviridae Infections D018178 1 associated lipids
Glucose Intolerance D018149 13 associated lipids
Amyloid Neuropathies D017772 1 associated lipids
Cytomegalovirus Retinitis D017726 2 associated lipids
Lichen Planus, Oral D017676 2 associated lipids
Hypophosphatemia D017674 1 associated lipids
Myelinolysis, Central Pontine D017590 1 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Mucinoses D017520 2 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Lichen Nitidus D017513 1 associated lipids
Lichenoid Eruptions D017512 1 associated lipids
Pyoderma Gangrenosum D017511 3 associated lipids
Porokeratosis D017499 1 associated lipids
Hidradenitis Suppurativa D017497 2 associated lipids
Hypopigmentation D017496 2 associated lipids
Hyperpigmentation D017495 11 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Polymyositis D017285 1 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Liver Failure, Acute D017114 11 associated lipids
IgG Deficiency D017099 1 associated lipids
IgA Deficiency D017098 2 associated lipids
Liver Failure D017093 5 associated lipids
Meningitis, Fungal D016921 1 associated lipids
Meningitis, Cryptococcal D016919 1 associated lipids
Arthritis, Reactive D016918 3 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Polyendocrinopathies, Autoimmune D016884 1 associated lipids
Feline Infectious Peritonitis D016766 1 associated lipids
Still's Disease, Adult-Onset D016706 2 associated lipids
Critical Illness D016638 13 associated lipids
Neoplasms, Second Primary D016609 4 associated lipids
Foot Ulcer D016523 4 associated lipids
Pemphigus, Benign Familial D016506 3 associated lipids
Fungemia D016469 2 associated lipids
Sweet Syndrome D016463 1 associated lipids
Granuloma Annulare D016460 1 associated lipids
Lymphoma, T-Cell, Cutaneous D016410 4 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Moura Penteado LA et al. Evaluation of the effect of tacrolimus on periodontitis induced in rats. 2017 Arch. Oral Biol. pmid:28399470
Ghaffari R et al. Tacrolimus Eye Drops as Adjunct Therapy in Severe Corneal Endothelial Rejection Refractory to Corticosteroids. 2017 Cornea pmid:28817391
Gouvêa ALF et al. BK polyomavirus nephropathy in two kidney transplant patients with distinct diagnostic strategies for BK virus and similar clinical outcomes: two case reports. 2017 J Med Case Rep pmid:28535782
Harada S et al. Complete remission of angiolymphoid hyperplasia with eosinophilia using topical tacrolimus. 2017 Eur J Dermatol pmid:28007668
Sinha A et al. Mycophenolate mofetil is inferior to tacrolimus in sustaining remission in children with idiopathic steroid-resistant nephrotic syndrome. 2017 Kidney Int. pmid:28318625
Saeki K et al. Endobronchial Lesions of Mycobacterium abscessus Infection in an Immunocompromised Patient. 2017 Am. J. Respir. Crit. Care Med. pmid:28199133
Ericson JE et al. A Systematic Literature Review Approach to Estimate the Therapeutic Index of Selected Immunosuppressant Drugs After Renal Transplantation. 2017 Ther Drug Monit pmid:28081041
Miyazaki D et al. Steroid-Sparing Effect of 0.1% Tacrolimus Eye Drop for Treatment of Shield Ulcer and Corneal Epitheliopathy in Refractory Allergic Ocular Diseases. 2017 Ophthalmology pmid:28017421
De Majumdar S et al. A Low Concentration of Tacrolimus/Semifluorinated Alkane (SFA) Eyedrop Suppresses Intraocular Inflammation in Experimental Models of Uveitis. 2017 Curr. Mol. Med. pmid:28782485
Larche M and McGonagle D A case of resistant spondyloarthritis (SpA) that responded to tacrolimus and mycophenolate treatment initiated at the time of renal transplantation for unrelated renal failure. 2017 Scand. J. Rheumatol. pmid:26971928