tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Hattori Y et al. | Influence of cytochrome P450 3A5 polymorphisms on viral infection incidence in kidney transplant patients treated with tacrolimus. | 2014 | Transplant. Proc. | pmid:24656015 |
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| Cusinato DA et al. | Relationship of CYP3A5 genotype and ABCB1 diplotype to tacrolimus disposition in Brazilian kidney transplant patients. | 2014 | Br J Clin Pharmacol | pmid:24528196 |
| Gérard C et al. | Determination of the most influential sources of variability in tacrolimus trough blood concentrations in adult liver transplant recipients: a bottom-up approach. | 2014 | AAPS J | pmid:24526611 |
| Kiiski V et al. | Long-term safety of topical pimecrolimus and topical tacrolimus in atopic blepharoconjunctivitis. | 2014 | JAMA Dermatol | pmid:24500107 |
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| Torres IB et al. | The Interplay between inflammation and fibrosis in kidney transplantation. | 2014 | Biomed Res Int | pmid:24991565 |
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| Sivakumar V et al. | Role of fludrocortisone in the management of tacrolimus-induced hyperkalemia in a renal transplant recipient. | 2014 | Saudi J Kidney Dis Transpl | pmid:24434399 |
| Yargui L et al. | Metabolic status of 1088 patients after renal transplantation: assessment of twelve years monitoring in Algiers Mustapha Hospital. | 2014 | Saudi J Kidney Dis Transpl | pmid:24434409 |
| Gounden V and Soldin SJ | Tacrolimus measurement: building a better immunoassay. | 2014 | Clin. Chem. | pmid:24415738 |
| Basu B | Ofatumumab for rituximab-resistant nephrotic syndrome. | 2014 | N. Engl. J. Med. | pmid:24670185 |
| Takeuchi T et al. | Post-marketing surveillance of the safety and effectiveness of tacrolimus in 3,267 Japanese patients with rheumatoid arthritis. | 2014 | Mod Rheumatol | pmid:24261753 |
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| Gijsen VM et al. | P450 oxidoreductase *28 (POR*28) and tacrolimus disposition in pediatric kidney transplant recipients--a pilot study. | 2014 | Ther Drug Monit | pmid:24089076 |
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| Schlegel A et al. | Hypothermic Oxygenated Perfusion (HOPE) downregulates the immune response in a rat model of liver transplantation. | 2014 | Ann. Surg. | pmid:25243553 |
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| Nasu R et al. | Favorable outcomes of tacrolimus compared with cyclosporine A for GVHD prophylaxis in HSCT for standard-risk hematological diseases. | 2014 | Ann. Hematol. | pmid:24590535 |
| Kujawski S et al. | Calcineurin regulates coordinated outgrowth of zebrafish regenerating fins. | 2014 | Dev. Cell | pmid:24561038 |
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| Baldo A et al. | Vitiligo, NB-UVB and tacrolimus: our experience in Naples. | 2014 | G Ital Dermatol Venereol | pmid:24566573 |
| Liu FL et al. | FKBP12 regulates the localization and processing of amyloid precursor protein in human cell lines. | 2014 | J. Biosci. | pmid:24499793 |
| Hao JC et al. | Effect of low-dose tacrolimus with mycophenolate mofetil on renal function following liver transplantation. | 2014 | World J. Gastroenterol. | pmid:25170222 |
| Parks AC et al. | Long-term clearance of linear porokeratosis with tacrolimus, 0.1%, ointment. | 2014 | JAMA Dermatol | pmid:24553841 |
| Peng L et al. | The calcineurin inhibitor tacrolimus reduces proteinuria in membranous nephropathy accompanied by a decrease in angiopoietin-like-4. | 2014 | PLoS ONE | pmid:25165975 |
| Favennec C et al. | Consideration of the switch from twice-daily to once-daily tacrolimus in pediatric kidney transplant in daily clinical practice: pharmacokinetic parameters, patient satisfaction and medical practices. | 2014 | Pediatr Transplant | pmid:25164065 |
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| Vattemi G et al. | Polymyositis in solid organ transplant recipients receiving tacrolimus. | 2014 | J. Neurol. Sci. | pmid:25130930 |
| Narabayashi K et al. | Oral tacrolimus for megacolon in patients with severe ulcerative colitis. | 2014 | Intern. Med. | pmid:25130105 |
| Amanova A et al. | Colchicine levels in chronic kidney diseases and kidney transplant recipients using tacrolimus. | 2014 | Clin Transplant | pmid:25125128 |
| Schmid S et al. | Volatility of serum creatinine relative to tacrolimus levels predicts kidney transplant rejection. | 2014 | Ann. Transplant. | pmid:25123847 |
| Caraveo G et al. | Calcineurin determines toxic versus beneficial responses to α-synuclein. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25122673 |
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| Farkas K et al. | Ability of different rescue therapies to save the bowel in acute, severe, steroid-refractory ulcerative colitis. | 2014 | Expert Rev Gastroenterol Hepatol | pmid:24738535 |
| Han JS et al. | Tacrolimus 0.1% ointment in the treatment of allergic contact dermatitis: a new approach. | 2014 | Int. J. Dermatol. | pmid:25070257 |
| Li T et al. | Effect of FK506 nanospheres on regeneration of allogeneic nerve after transplant. | 2014 | Asian Pac J Trop Med | pmid:25066398 |
| Hamilton BK and Kalaycio M | Maximizing the benefits of mycophenolate mofetil as graft-versus-host disease prophylaxis. | 2014 | Biol. Blood Marrow Transplant. | pmid:25065905 |
| Miyauchi T et al. | Evidence for the therapeutic efficacy of either mild hypothermia or oxygen radical scavengers after repetitive mild traumatic brain injury. | 2014 | J. Neurotrauma | pmid:24341607 |
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| Inaba A et al. | Cerebral toxoplasmosis after umbilical cord blood transplantation diagnosed by the detection of anti-toxoplasma specific IgM antibody in cerebrospinal fluid. | 2014 | Rinsho Ketsueki | pmid:24850458 |
| Kurzawski M et al. | Impact of PPARA and POR polymorphisms on tacrolimus pharmacokinetics and new-onset diabetes in kidney transplant recipients. | 2014 | Pharmacogenet. Genomics | pmid:24921414 |
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| Helmschrott M et al. | Superior rejection profile during the first 24 months after heart transplantation under tacrolimus as baseline immunosuppressive regimen. | 2014 | Drug Des Devel Ther | pmid:25246772 |
| Parvizi Z et al. | Association between E23K variant in KCNJ11 gene and new-onset diabetes after liver transplantation. | 2014 | Mol. Biol. Rep. | pmid:24996284 |
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| Andrade-Sierra J et al. | Early steroid withdrawal in a renal transplant cohort treated with tacrolimus, mycophenolate mofetil and basiliximab. | 2014 | Nefrologia | pmid:24658197 |
| Zhao X et al. | [A retrospective cohort study regarding the effect of sirolimus-based immunosuppression protocol on the long-term survival of hepatocellular carcinoma patients after liver transplantation]. | 2014 | Zhonghua Wai Ke Za Zhi | pmid:24924566 |
| Kanyshkova T et al. | Regionally specific expression of high-voltage-activated calcium channels in thalamic nuclei of epileptic and non-epileptic rats. | 2014 | Mol. Cell. Neurosci. | pmid:24914823 |
| Hebral AL et al. | Pregnancy after kidney transplantation: outcome and anti-human leucocyte antigen alloimmunization risk. | 2014 | Nephrol. Dial. Transplant. | pmid:24914091 |
| Zhu H et al. | Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF‑1α expression in vivo. | 2014 | Mol Med Rep | pmid:24912495 |
| Saito E et al. | Efficacy of salvage therapy and its effect on operative outcomes in patients with ulcerative colitis. | 2014 | Digestion | pmid:24458114 |
| Song L et al. | Effects of ASKP1240 combined with tacrolimus or mycophenolate mofetil on renal allograft survival in Cynomolgus monkeys. | 2014 | Transplantation | pmid:24992357 |
| Hayes D et al. | Alternative tacrolimus and sirolimus regimen associated with rapid resolution of posterior reversible encephalopathy syndrome after lung transplantation. | 2014 | Pediatr. Neurol. | pmid:24405697 |
| Hosohata K et al. | Association between CYP3A5 genotypes in graft liver and increase in tacrolimus biotransformation from steroid treatment in living-donor liver transplant patients. | 2014 | Drug Metab. Pharmacokinet. | pmid:23955548 |
| Lin T et al. | A Chinese girl with novel PLCE1 mutations and proliferation of the mesangium responded to tacrolimus therapy. | 2014 | Nephrology (Carlton) | pmid:24533735 |
| Foroncewicz B et al. | Cyclosporine is superior to tacrolimus in liver transplant recipients with recurrent psoriasis. | 2014 | Ann. Transplant. | pmid:25163829 |
| Oda K et al. | In vitro experimental system for evaluating inhibitory effect of investigational drugs on P-glycoprotein-mediated transcellular transport of tacrolimus (FK506). | 2014 | Biopharm Drug Dispos | pmid:24822242 |
| Wang Z et al. | Influence of TLR4 rs1927907 locus polymorphisms on tacrolimus pharmacokinetics in the early stage after liver transplantation. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24820765 |
| Akchurin OM et al. | Medication adherence in the transition of adolescent kidney transplant recipients to the adult care. | 2014 | Pediatr Transplant | pmid:24820521 |
| Kern G et al. | Tacrolimus increases Nox4 expression in human renal fibroblasts and induces fibrosis-related genes by aberrant TGF-beta receptor signalling. | 2014 | PLoS ONE | pmid:24816588 |
| Sánchez L et al. | Topical tacrolimus for recurrent penile Crohn's disease. | 2014 | J Crohns Colitis | pmid:24815787 |
| Colom H et al. | Pharmacokinetic modeling of enterohepatic circulation of mycophenolic acid in renal transplant recipients. | 2014 | Kidney Int. | pmid:24402086 |
| Castronovo G et al. | The effect of nonsurgical periodontal treatment on the severity of drug-induced gingival overgrowth in transplant patients. | 2014 | Quintessence Int | pmid:24389563 |
| Bergmann TK et al. | Comparison of the influence of cyclosporine and tacrolimus on the pharmacokinetics of prednisolone in adult male kidney transplant recipients. | 2014 | Clin Drug Investig | pmid:24385281 |
| Yap DY et al. | Long-term data on tacrolimus treatment in lupus nephritis. | 2014 | Rheumatology (Oxford) | pmid:24996908 |
| Ishikawa Y and Bächinger HP | A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis. | 2014 | J. Biol. Chem. | pmid:24821723 |
| Varghese J et al. | Tacrolimus-related adverse effects in liver transplant recipients: its association with trough concentrations. | 2014 | Indian J Gastroenterol | pmid:24740447 |
| Calabrese B et al. | Activity-dependent dendritic spine shrinkage and growth involve downregulation of cofilin via distinct mechanisms. | 2014 | PLoS ONE | pmid:24740405 |
| Lesche D et al. | CYP3A5*3 and POR*28 genetic variants influence the required dose of tacrolimus in heart transplant recipients. | 2014 | Ther Drug Monit | pmid:24739669 |
| Langers P et al. | Limited sampling model for advanced mycophenolic acid therapeutic drug monitoring after liver transplantation. | 2014 | Ther Drug Monit | pmid:24081208 |
| Lee SK et al. | Overexpression of the putative extracytoplasmic function sigma (σ) factor FujE enhances FK506 production in Streptomyces sp. strain KCCM 11116P. | 2014 | Can. J. Microbiol. | pmid:24869633 |
| van der Vusse ML et al. | Helicobacter canis bacteremia in a renal transplant patient. | 2014 | Transpl Infect Dis | pmid:24372779 |
| Földes G et al. | Immunosuppressive agents modulate function, growth, and survival of cardiomyocytes and endothelial cells derived from human embryonic stem cells. | 2014 | Stem Cells Dev. | pmid:24192059 |
| da Cunha Filho RR et al. | "Angular" plasma cell cheilitis. | 2014 | Dermatol. Online J. | pmid:24656273 |
| Nakamura A et al. | Effects of elevated tacrolimus trough levels in association with infectious enteritis on graft function in renal transplant recipients. | 2014 | Transplant. Proc. | pmid:24656020 |